The DOI matches its Crossref record.
A Physical Map of the Escherichia coli K12 Genome
Abstract
A physical map of a genome is the structure of its DNA. Construction of such a map is a first step in the complete characterization of that DNA. The restriction endonuclease Not I cuts the genome of Escherichia coli K12 into 22 DNA fragments ranging from 20 kilobases (20,000 base pairs) to 1000 kilobases. These can be separated by pulsed field gel electrophoresis. The order of the fragments in the genome was determined from available E. coli genetic information and analysis of partial digest patterns. The resulting ordered set of fragments is a macrorestriction map. This map facilitates genetic and molecular studies on E. coli , and its construction serves as a model for further endeavors on larger genomes.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
A constant rate of spontaneous mutation in DNA-based microbes.
Drake, J. W. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.16.7160 · Cited by 1,199
Social and developmental biology of the myxobacteria
Shimkets, L. J. (1990) · Microbiological Reviews · doi:10.1128/mmbr.54.4.473-501.1990 · Cited by 388
Organization of the bacterial chromosome
KRAWIEC, S., & Riley, M. (1990) · Microbiological Reviews · doi:10.1128/mmbr.54.4.502-539.1990 · Cited by 386
The dam and dcm strains of Escherichia coli — a review
Palmer, B. R., & Marinus, M. G. (1994) · Gene · doi:10.1016/0378-1119(94)90597-5 · Cited by 275
Metadata
- Authors
- Smith, C. L., Econome, J. G., Schutt, A., Klco, S., & Cantor, C. R.
- Venue
- Science
- Published
- 1987-06-12
- Volume
- 236
- Issue
- 4807
- Pages
- 1448-1453
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1965334884
- Cited by
- 399
- References
- 0
- FWCI
- 26.87
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: A Physical Map of the Escherichia coli K12 Genome. https://app.cochat.ai/papers/10.1126/science.3296194
- The paper
- Smith, C. L., Econome, J. G., Schutt, A., Klco, S., & Cantor, C. R. (1987). A Physical Map of the Escherichia coli K12 Genome. Science. https://doi.org/10.1126/science.3296194
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
