The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Molecular Cloning of Odorant-Binding Protein: Member of a Ligand Carrier Family
Abstract
Odorant-binding protein (OBP) is found in nasal epithelium, and it selectively binds odorants. Three complementary DNAs encoding rat odorant-binding protein have now been cloned and sequenced. One clone contains an open reading frame predicted to encode an 18,091-dalton protein. RNA blot analysis confirms the localization of OBP messenger RNA in the nasal epithelium. This OBP has 33 percent amino acid identity to α 2 -microglobulin, a secreted plasma protein. Other members of an α 2 -microglobulin superfamily bind and transport hydrophobic ligands. Thus, OBP probably binds and carries odorants within the nasal epithelium to putative olfactory receptors.
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Cites
The three‐dimensional structure of retinol‐binding protein.
Newcomer, M. E., Jones, T. A., Aqvist, J., Sundelin, J., Eriksson, U., Rask, L., & Peterson, P. A. (1984) · The EMBO Journal · doi:10.1002/j.1460-2075.1984.tb01995.x · Cited by 405
Cited by
The lipocalin protein family: structure and function
FLOWER, D. R. (1996) · Biochemical Journal · doi:10.1042/bj3180001 · Cited by 1,679
MECHANISMS OF OLFACTORY DISCRIMINATION: Converging Evidence for Common Principles Across Phyla
Hildebrand, J. G., & Shepherd, G. M. (1997) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.20.1.595 · Cited by 1,074
Olfaction: Diverse Species, Conserved Principles
Ache, B. W., & Young, J. M. (2005) · Neuron · doi:10.1016/j.neuron.2005.10.022 · Cited by 655
Identification of Ligands for Olfactory Receptors by Functional Expression of a Receptor Library
Krautwurst, D., Yau, K.-W., & Reed, R. R. (1998) · Cell · doi:10.1016/s0092-8674(00)81716-x · Cited by 606
Self-citationPutative Drosophila pheromone-binding proteins expressed in a subregion of the olfactory system.
McKenna, M. P., Hekmat-Scafe, D. S., Gaines, P., & Carlson, J. R. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)34013-9 · Cited by 364
Metadata
- Authors
- Pevsner, J., Reed, R. R., Feinstein, P. G., & Snyder, S. H.
- Venue
- Science
- Published
- 1988-07-15
- Volume
- 241
- Issue
- 4863
- Pages
- 336-339
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1977743117
- Cited by
- 250
- References
- 1
- FWCI
- 16.21
- Type
- journal article
- Language
- en
- Open access
- closed
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- Pevsner, J., Reed, R. R., Feinstein, P. G., & Snyder, S. H. (1988). Molecular Cloning of Odorant-Binding Protein: Member of a Ligand Carrier Family. Science. https://doi.org/10.1126/science.3388043
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
