The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Delay of Disease Development in Transgenic Plants That Express the Tobacco Mosaic Virus Coat Protein Gene
Abstract
A chimeric gene containing a cloned cDNA of the coat protein (CP) gene of tobacco mosaic virus (TMV) was introduced into tobacco cells on a Ti plasmid of Agrobacterium tumefaciens from which tumor inducing genes had been removed. Plants regenerated from transformed cells expressed TMV mRNA and CP as a nuclear trait. Seedlings from self-fertilized transgenic plants were inoculated with TMV and observed for development of disease symptoms. The seedlings that expressed the CP gene were delayed in symptom development and 10 to 60 percent of the transgenic plants failed to develop symptoms for the duration of the experiments. Increasing the concentration of TMV in the inoculum shortened the delay in appearance of symptoms. The results of these experiments indicate that plants can be genetically transformed for resistance to virus disease development.
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Cites
Bradford, M. M. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90527-3 · Cited by 255,302
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
LAEMMLI, U. K. (1970) · Nature · doi:10.1038/227680a0 · Cited by 249,961
Cited by
Transposable Elements, Epigenetics, and Genome Evolution
Fedoroff, N. V. (2012) · Science · doi:10.1126/science.338.6108.758 · Cited by 634
Metadata
- Authors
- Abel, P. P., Nelson, R. S., De, B., Hoffmann, N., Rogers, S. G., Fraley, R. T., & Beachy, R. N.
- Venue
- Science
- Published
- 1986-05-09
- Volume
- 232
- Issue
- 4751
- Pages
- 738-743
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1995273609
- Cited by
- 1,321
- References
- 2
- FWCI
- 76.75
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Delay of Disease Development in Transgenic Plants That Express the Tobacco Mosaic Virus Coat Protein Gene. https://app.cochat.ai/papers/10.1126/science.3457472
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- Abel, P. P., Nelson, R. S., De, B., Hoffmann, N., Rogers, S. G., Fraley, R. T., & Beachy, R. N. (1986). Delay of Disease Development in Transgenic Plants That Express the Tobacco Mosaic Virus Coat Protein Gene. Science. https://doi.org/10.1126/science.3457472
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