The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Oxytocin Secretion in Response to Cholecystokinin and Food: Differentiation of Nausea from Satiety
Abstract
Administration of cholecystokinin (CCK) to rats caused a dose-dependent increase in plasma levels of the neurohypophyseal hormone oxytocin (OT). The OT secretion was comparable to that found in response to nausea-producing chemical agents that cause learned taste aversions. The effect of CCK on OT secretion was blunted after gastric vagotomy, as was the inhibition of food intake induced by CCK. Food ingestion also led to elevated plasma OT in rats, but CCK and aversive agents caused even greater OT stimulation. Thus, after administration of large doses of CCK, vagally mediated activation of central nausea pathways seems to be predominantly responsible for the subsequent decrease in food intake. Despite their dissimilar affective states, both nausea and satiety may activate a common hypothalamic oxytocinergic pathway that controls the inhibition of ingestion.
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Cites
Cholecystokinin decreases food intake in rats.
Gibbs, J., Young, R. C., & Smith, G. P. (1973) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0034870 · Cited by 1,491
Garcia, J., Hankins, W. G., & Rusiniak, K. W. (1974) · Science · doi:10.1126/science.185.4154.824 · Cited by 1,123
Paraventricular Nucleus:A Site for the Integration of Neuroendocrine and Autonomic Mechanisms
Swanson, L. W., & Sawchenko, P. E. (1980) · Neuroendocrinology · doi:10.1159/000123111 · Cited by 997
Abdominal Vagotomy Blocks the Satiety Effect of Cholecystokinin in the Rat
Smith, G. P., Jerome, C., Cushin, B. J., Eterno, R., & Simansky, K. J. (1981) · Science · doi:10.1126/science.7268408 · Cited by 804
Cholecystokinin elicits the complete behavioral sequence of satiety in rats.
Antin, J., Gibbs, J., Holt, J., Young, R. C., & Smith, G. P. (1975) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0077040 · Cited by 613
C-terminal octapeptide of cholecystokinin decreases food intake in man
Kissileff, H. R., Pi-Sunyer, F. X., Thornton, J., & Smith, G. P. (1981) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/34.2.154 · Cited by 598
Paraventricular nucleus: A primary site mediating adrenergic stimulation of feeding and drinking
Leibowitz, S. F. (1978) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(78)90333-7 · Cited by 439
Hypothalamic paraventricular nucleus lesions produce overeating and obesity in the rat
Leibowitz, S. F., Hammer, N. J., & Chang, K. (1981) · Physiology & Behavior · doi:10.1016/0031-9384(81)90366-8 · Cited by 382
Cholecystokinin produces bait shyness in rats
DEUTSCH, J. A., & HARDY, W. T. (1977) · Nature · doi:10.1038/266196a0 · Cited by 188
Oxytocin and vasopressin secretion in response to stimuli producing learned taste aversions in rats.
Verbalis, J. G., McHale, C. M., Gardiner, T. W., & Stricker, E. M. (1986) · Behavioral Neuroscience · doi:10.1037//0735-7044.100.4.466 · Cited by 172
Self-citation
Cited by
Nelson, E. E., & Panksepp, J. (1998) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(97)00052-3 · Cited by 688
Larsen, P. J., Tang-Christensen, M., Holst, J. J., & Ørskov, C. (1997) · Neuroscience · doi:10.1016/s0306-4522(96)00434-4 · Cited by 663
Eliava, M., Melchior, M., Knobloch-Bollmann, H. S., Wahis, J., da Silva Gouveia, M., Tang, Y., Ciobanu, A. C., Triana del Rio, R., Roth, L. C., Althammer, F., et al. (2016) · Neuron · doi:10.1016/j.neuron.2016.01.041 · Cited by 409
Argiolas, A., & Gessa, G. L. (1991) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(05)80002-8 · Cited by 366
Dendritic Release of Vasopressin and Oxytocin
Ludwig (1998) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.1998.00279.x · Cited by 342
Metadata
- Authors
- Verbalis, J. G., McCann, M. J., McHale, C. M., & Stricker, E. M.
- Venue
- Science
- Published
- 1986-06-13
- Volume
- 232
- Issue
- 4756
- Pages
- 1417-1419
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2004135885
- Cited by
- 354
- References
- 19
- FWCI
- 8.16
- Type
- journal article
- Language
- en
- Open access
- closed
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- Verbalis, J. G., McCann, M. J., McHale, C. M., & Stricker, E. M. (1986). Oxytocin Secretion in Response to Cholecystokinin and Food: Differentiation of Nausea from Satiety. Science. https://doi.org/10.1126/science.3715453
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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