The DOI matches its Crossref record.
Flow Control Among Microvessels Coordinated by Intercellular Conduction
Abstract
Optimal distribution of blood flow requires coordination of vasodilation among resistance vessels. During hyperemia, blood vessels dilate upstream from the initiating stimulus. Spreading vasodilation independent of flow changes has not been previously demonstrated. In the present study, iontophoresis of acetylcholine adjacent to single hamster cheek pouch arterioles in situ (diameter, 20 to 37 micrometers) induced a rapid bidirectional dilation that was not attenuated when blood flow was eliminated with vascular occlusion. This finding indicates that a vasodilatory stimulus is conducted along the arteriole and demonstrates the existence of a mechanism of intercellular communication that is capable of coordinating diameter changes among resistance vessels.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Joyner, M. J., & Casey, D. P. (2015) · Physiological Reviews · doi:10.1152/physrev.00035.2013 · Cited by 833
Regulation of large cerebral arteries and cerebral microvascular pressure.
Faraci, F. M., & Heistad, D. D. (1990) · Circulation Research · doi:10.1161/01.res.66.1.8 · Cited by 608
Iadecola, C. (1993) · Trends in Neurosciences · doi:10.1016/0166-2236(93)90156-g · Cited by 473
Impaired conduction of vasodilation along arterioles in connexin40-deficient mice
de Wit, C., Roos, F., Bolz, S.-S., Kirchhoff, S., Krüger, O., Willecke, K., & Pohl, U. (2000) · Circulation Research · doi:10.1161/01.res.86.6.649 · Cited by 338
Gladwin, M. T., Raat, N. J. H., Shiva, S., Dezfulian, C., Hogg, N., Kim-Shapiro, D. B., & Patel, R. P. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00407.2006 · Cited by 329
Metadata
- Authors
- Segal, S. S., & Duling, B. R.
- Venue
- Science
- Published
- 1986-11-14
- Volume
- 234
- Issue
- 4778
- Pages
- 868-870
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2021724833
- Cited by
- 299
- References
- 0
- FWCI
- 3.81
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Flow Control Among Microvessels Coordinated by Intercellular Conduction. https://app.cochat.ai/papers/10.1126/science.3775368
- The paper
- Segal, S. S., & Duling, B. R. (1986). Flow Control Among Microvessels Coordinated by Intercellular Conduction. Science. https://doi.org/10.1126/science.3775368
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
