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Cited by 516

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A Sexually Dimorphic Nucleus in the Human Brain

Open access
Swaab, D. F., Fliers, E.·1985·Science

Abstract

A sexually dimorphic cell group is described in the preoptic area of the human hypothalamus. Morphometric analysis revealed that the volume of this nucleus is 2.5 ± 0.6 times (mean ± standard error of the mean) as large in men as in women, and contains 2.2 ± 0.5 times as many cells. Between the ages of 10 and 93 years, the nucleus decreases greatly in volume and in cell number. Although no function has yet been established for this nucleus, it is located within an area that is essential for gonadotropin release and sexual behavior in other mammals.

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Metadata

Authors
Swaab, D. F., & Fliers, E.
Venue
Science
Published
1985-05-31
Volume
228
Issue
4703
Pages
1112-1115
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W1966770839
Cited by
516
References
0
FWCI
24.48
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: A Sexually Dimorphic Nucleus in the Human Brain. https://app.cochat.ai/papers/10.1126/science.3992248
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Swaab, D. F., & Fliers, E. (1985). A Sexually Dimorphic Nucleus in the Human Brain. Science. https://doi.org/10.1126/science.3992248

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.