The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Regulation of Gene Expression: Possible Role of Repetitive Sequences
Abstract
Large contrasts are observed between the messenger RNA populations of different tissues and of embryos at different stages of development. Nevertheless, coding sequences for genes not expressed in a cell appear to be present in its nuclear RNA. Though many nuclear RNA transcripts of single copy DNA sequences are held in common between tissues, an additional set, probably consisting of non-message sequences, is not shared. Nuclear RNA also contains transcripts of repetitive DNA sequences. Certain repeat families are represented at high levels in the nuclear RNA of particular tissues and much lower levels in others. It is surprising that both complements of most repeat sequences are present in nuclear RNA. These observations lead to a model for regulation of gene expression in which the formation of repetitive RNA-RNA duplexes controls the production of messenger RNA.
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Needleman, S. B., & Wunsch, C. D. (1970) · Journal of Molecular Biology · doi:10.1016/0022-2836(70)90057-4 · Cited by 11,288
Sea urchin embryo mRNA sequences expressed in the nuclear RNA of adult tissues
Wold, B. J., Klein, W. H., Hough-Evans, B. R., Britten, R. J., & Davidson, E. H. (1978) · Cell · doi:10.1016/0092-8674(78)90348-3 · Cited by 128
Self-citation
Cited by
Ten things you should know about transposable elements
Bourque, G., Burns, K. H., Gehring, M., Gorbunova, V., Seluanov, A., Hammell, M., Imbeault, M., Izsvák, Z., Levin, H. L., Macfarlan, T. S., et al. (2018) · Genome Biology · doi:10.1186/s13059-018-1577-z · Cited by 1,430
LINE-1 elements in structural variation and disease
Beck, C. R., Garcia-Perez, J. L., Badge, R. M., & Moran, J. V. (2011) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-082509-141802 · Cited by 615
Base sequence studies of 300 nucleotide renatured repeated human DNA clones
Deininger, P. L., Jolly, D. J., Rubin, C. M., Friedmann, T., & Schmid, C. W. (1981) · Journal of Molecular Biology · doi:10.1016/0022-2836(81)90219-9 · Cited by 586
Replication Timing of Genes and Middle Repetitive Sequences
Goldman, M. A., Holmquist, G. P., Gray, M. C., Caston, L. A., & Nag, A. (1984) · Science · doi:10.1126/science.6719109 · Cited by 538
Normalization and subtraction: two approaches to facilitate gene discovery.
Bonaldo, M. F., Lennon, G., & Soares, M. B. (1996) · Genome Research · doi:10.1101/gr.6.9.791 · Cited by 522
Metadata
- Authors
- Davidson, E. H., & Britten, R. J.
- Venue
- Science
- Published
- 1979-06-08
- Volume
- 204
- Issue
- 4397
- Pages
- 1052-1059
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2017216895
- Cited by
- 568
- References
- 2
- FWCI
- 36.09
- Type
- journal article
- Language
- en
- Open access
- closed
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