The DOI matches its Crossref record.
Specific Chromosome Defect Associated with Human Small-Cell Lung Cancer: Deletion 3p(14-23)
Abstract
A specific, acquired chromosomal abnormality (deletion 3p) has been found in at least one chromosome 3 in 100 percent of the metaphases in 12 of 12 cell lines cultured from human small-cell lung cancer tissue and in 2-day tumor culture specimens from three patients. Analysis of the shortest region of overlap shows the deletion to be 3p(14-23). This specific change was not seen in five of five lung cancer cell lines other than small-cell lung cancer or in two lymphoblastoid lines cultured from cells of small-cell lung cancer patients whose tumors had the 3p deletion.
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Citations
Cited by
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Metadata
- Authors
- Whang-Peng, J., Kao-Shan, C. S., Lee, E. C., Bunn, P. A., Carney, D. N., Gazdar, A. F., & Minna, J. D.
- Venue
- Science
- Published
- 1982-01-08
- Volume
- 215
- Issue
- 4529
- Pages
- 181-182
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2030480699
- Cited by
- 452
- References
- 0
- FWCI
- 17.37
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Specific Chromosome Defect Associated with Human Small-Cell Lung Cancer: Deletion 3p(14-23). https://app.cochat.ai/papers/10.1126/science.6274023
- The paper
- Whang-Peng, J., Kao-Shan, C. S., Lee, E. C., Bunn, P. A., Carney, D. N., Gazdar, A. F., & Minna, J. D. (1982). Specific Chromosome Defect Associated with Human Small-Cell Lung Cancer: Deletion 3p(14-23). Science. https://doi.org/10.1126/science.6274023
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
