The DOI matches its Crossref record.
Induction of Interleukin 2 Messenger RNA Inhibited by Cyclosporin A
Abstract
Cyclosporin A blocked production of the lymphokine interleukin 2 by activated T lymphocytes. In a human and a murine cell line this inhibition reflected an absence of interleukin 2 messenger RNA. Under conditions in which these cells are normally stimulated to secrete high levels of interleukin 2, they failed to do so in the presence of cyclosporin A. In both cell lines this failure was accompanied by an absence of interleukin 2 messenger accumulation.
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Citations
Cited by
The mechanism of action of cyclosporin A and FK506
Schreiber, S. L., & Crabtree, G. R. (1992) · Immunology Today · doi:10.1016/0167-5699(92)90111-j · Cited by 2,127
pl Bl5: A cDNA Clone of the Rat mRNA Encoding Cyclophilin
DANIELSON, P. E., FORSS-PETTER, S., BROW, M. A., CALAVETTA, L., DOUGLASS, J., MILNER, R. J., & SUTCLIFFE, J. G. (1988) · DNA · doi:10.1089/dna.1988.7.261 · Cited by 1,020
Vacuolating encephalitis in mice infected by human coronavirus OC43
Jacomy, H., & Talbot, P. J. (2003) · Virology · doi:10.1016/s0042-6822(03)00323-4 · Cited by 128
Effect of cyclosporine on blood pressure
Robert, N., Wong, G. W., & Wright, J. M. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007893 · Cited by 44
Metadata
- Authors
- Elliott, J. F., Lin, Y., Mizel, S. B., Bleackley, R. C., Harnish, D. G., & Paetkau, V.
- Venue
- Science
- Published
- 1984-12-21
- Volume
- 226
- Issue
- 4681
- Pages
- 1439-1441
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2081790950
- Cited by
- 395
- References
- 0
- FWCI
- 9.18
- Type
- journal article
- Language
- en
- Open access
- closed
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- Elliott, J. F., Lin, Y., Mizel, S. B., Bleackley, R. C., Harnish, D. G., & Paetkau, V. (1984). Induction of Interleukin 2 Messenger RNA Inhibited by Cyclosporin A. Science. https://doi.org/10.1126/science.6334364
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
