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Perfluorochemical Emulsions Can Increase Tumor Radiosensitivity
Abstract
An oxygen-carrying perfluorochemical emulsion enhanced the effectiveness of radiation therapy in two transplantable solid tumors in mice. The perfluorochemical emulsion had no effect on tumor growth after x-irradiation, but delayed tumor growth significantly when administered to oxygen-breathing mice before or during irradiation.
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Cited by
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
Zhou, Z., Song, J., Nie, L., & Chen, X. (2016) · Chemical Society Reviews · doi:10.1039/c6cs00271d · Cited by 2,098
Gatenby, R. A., Kessler, H. B., Rosenblum, J. S., Coia, L. R., Moldofsky, P. J., Hartz, W. H., & Broder, G. J. (1988) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/0360-3016(88)90002-8 · Cited by 798
Song, G., Liang, C., Yi, X., Zhao, Q., Cheng, L., Yang, K., & Liu, Z. (2016) · Advanced Materials · doi:10.1002/adma.201504617 · Cited by 587
Teicher, B. A. (1994) · Cancer and Metastasis Reviews · doi:10.1007/bf00689633 · Cited by 563
Self-citationTumor hypoxia: its impact on cancer therapy
Moulder, J. E., & Rockwell, S. (1987) · Cancer and Metastasis Reviews · doi:10.1007/bf00055376 · Cited by 414
Metadata
- Authors
- Teicher, B. A., & Rose, C. M.
- Venue
- Science
- Published
- 1984-03-02
- Volume
- 223
- Issue
- 4639
- Pages
- 934-936
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1986441241
- Cited by
- 204
- References
- 0
- FWCI
- 21.93
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Perfluorochemical Emulsions Can Increase Tumor Radiosensitivity. https://app.cochat.ai/papers/10.1126/science.6695191
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- Teicher, B. A., & Rose, C. M. (1984). Perfluorochemical Emulsions Can Increase Tumor Radiosensitivity. Science. https://doi.org/10.1126/science.6695191
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.