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Selective Photothermolysis: Precise Microsurgery by Selective Absorption of Pulsed Radiation
Abstract
Suitably brief pulses of selectively absorbed optical radiation can cause selective damage to pigmented structures, cells, and organelles in vivo. Precise aiming is unnecessary in this unique form of radiation injury because inherent optical and thermal properties provide target selectivity. A simple, predictive model is presented. Selective damage to cutaneous microvessels and to melanosomes within melanocytes is shown after 577-nanometer (3 × 10 -7 second) and 351-nanometer (2 × 10 -8 second) pulses, respectively. Hemodynamic, histological, and ultrastructural responses are discussed.
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Cited by
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Huang, X., Jain, P. K., El-Sayed, I. H., & El-Sayed, M. A. (2008) · Lasers in Medical Science · doi:10.1007/s10103-007-0470-x · Cited by 2,376
Mechanisms of Pulsed Laser Ablation of Biological Tissues
Vogel, A., & Venugopalan, V. (2003) · Chemical Reviews · doi:10.1021/cr010379n · Cited by 1,918
Chemical and Instrumental Approaches to Treat Hyperpigmentation
Briganti, S., Camera, E., & Picardo, M. (2003) · Pigment Cell Research · doi:10.1034/j.1600-0749.2003.00029.x · Cited by 837
Photoaging: mechanisms and repair
Rabe, J. H., Mamelak, A. J., McElgunn, P. J. S., Morison, W. L., & Sauder, D. N. (2006) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2005.05.010 · Cited by 610
The spectrum of laser skin resurfacing: Nonablative, fractional, and ablative laser resurfacing
Alexiades-Armenakas, M. R., Dover, J. S., & Arndt, K. A. (2008) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2008.01.003 · Cited by 580
Metadata
- Authors
- Anderson, R. R., & Parrish, J. A.
- Venue
- Science
- Published
- 1983-04-29
- Volume
- 220
- Issue
- 4596
- Pages
- 524-527
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2158831156
- Cited by
- 3,447
- References
- 0
- FWCI
- 22.94
- Type
- journal article
- Language
- en
- Open access
- closed
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- Anderson, R. R., & Parrish, J. A. (1983). Selective Photothermolysis: Precise Microsurgery by Selective Absorption of Pulsed Radiation. Science. https://doi.org/10.1126/science.6836297
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
