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Cited by 384

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Magnesium Deficiency Produces Spasms of Coronary Arteries: Relationship to Etiology of Sudden Death Ischemic Heart Disease

Turlapaty, Prasad D. M. V., Altura, Burton M.·1980·Science

Abstract

Isolated coronary arteries from dogs were incubated in Krebs-Ringer bicarbonate solution and exposed to normal, high, and low concentrations of magnesium in the medium. Sudden withdrawal of magnesium from the medium increased whereas high concentrations of magnesium decreased the basal tension of the arteries. The absence of magnesium in the medium significantly potentiated the contractile responses of both small and large coronary arteries to norepinephrine, acetylcholine, serotonin, angiotensin, and potassium. These data support the hypothesis that magnesium deficiency, associated with sudden death ischemic heart disease, produces coronary arterial spasm.

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Metadata

Authors
Turlapaty, P. D. M. V., & Altura, B. M.
Venue
Science
Published
1980-04-11
Volume
208
Issue
4440
Pages
198-200
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W1986086928
Cited by
384
References
0
FWCI
11.19
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Magnesium Deficiency Produces Spasms of Coronary Arteries: Relationship to Etiology of Sudden Death Ischemic Heart Disease. https://app.cochat.ai/papers/10.1126/science.7361117
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Turlapaty, P. D. M. V., & Altura, B. M. (1980). Magnesium Deficiency Produces Spasms of Coronary Arteries: Relationship to Etiology of Sudden Death Ischemic Heart Disease. Science. https://doi.org/10.1126/science.7361117

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.