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Magnesium Deficiency Produces Spasms of Coronary Arteries: Relationship to Etiology of Sudden Death Ischemic Heart Disease
Abstract
Isolated coronary arteries from dogs were incubated in Krebs-Ringer bicarbonate solution and exposed to normal, high, and low concentrations of magnesium in the medium. Sudden withdrawal of magnesium from the medium increased whereas high concentrations of magnesium decreased the basal tension of the arteries. The absence of magnesium in the medium significantly potentiated the contractile responses of both small and large coronary arteries to norepinephrine, acetylcholine, serotonin, angiotensin, and potassium. These data support the hypothesis that magnesium deficiency, associated with sudden death ischemic heart disease, produces coronary arterial spasm.
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Cited by
Magnesium Status in Alzheimer’s Disease: A Systematic Review
Veronese, N., Zurlo, A., Solmi, M., Luchini, C., Trevisan, C., Bano, G., Manzato, E., Sergi, G., & Rylander, R. (2016) · American Journal of Alzheimer's Disease & Other Dementias® · doi:10.1177/1533317515602674 · Cited by 64
Alcohol consumption, anger and hostility: A link to coronary heart disease
Schonwetter, D. J., & Janisse, M. P. (1991) · Personality and Individual Differences · doi:10.1016/0191-8869(91)90034-9 · Cited by 17
Metadata
- Authors
- Turlapaty, P. D. M. V., & Altura, B. M.
- Venue
- Science
- Published
- 1980-04-11
- Volume
- 208
- Issue
- 4440
- Pages
- 198-200
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1986086928
- Cited by
- 384
- References
- 0
- FWCI
- 11.19
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Magnesium Deficiency Produces Spasms of Coronary Arteries: Relationship to Etiology of Sudden Death Ischemic Heart Disease. https://app.cochat.ai/papers/10.1126/science.7361117
- The paper
- Turlapaty, P. D. M. V., & Altura, B. M. (1980). Magnesium Deficiency Produces Spasms of Coronary Arteries: Relationship to Etiology of Sudden Death Ischemic Heart Disease. Science. https://doi.org/10.1126/science.7361117
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.