The DOI matches its Crossref record.
A Receptor for the Malarial Parasite Plasmodium vivax : the Erythrocyte Chemokine Receptor
Abstract
Plasmodium vivax and P. falciparum are the major causes of human malaria, except in sub-Saharan Africa where people lack the Duffy blood group antigen, the erythrocyte receptor for P. vivax . Duffy negative human erythrocytes are resistant to invasion by P. vivax and the related monkey malaria, P. knowlesi . Several lines of evidence in the present study indicate that the Duffy blood group antigen is the erythrocyte receptor for the chemokines interleukin-8 (IL-8) and melanoma growth stimulatory activity (MGSA). First, IL-8 binds minimally to Duffy negative erythrocytes. Second, a monoclonal antibody to the Duffy blood group antigen blocked binding of IL-8 and other chemokines to Duffy positive erythrocytes. Third, both MGSA and IL-8 blocked the binding of the parasite ligand and the invasion of human erythrocytes by P. knowlesi , suggesting the possibility of receptor blockade for anti-malarial therapy.
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Liu, R., Paxton, W. A., Choe, S., Ceradini, D., Martin, S. R., Horuk, R., MacDonald, M. E., Stuhlmann, H., Koup, R. A., & Landau, N. R. (1996) · Cell · doi:10.1016/s0092-8674(00)80110-5 · Cited by 3,074
Self-citationInternational Union of Pharmacology. XXII. Nomenclature for Chemokine Receptors
Murphy, P. M., Baggiolini, M., Charo, I. F., Hébert, C. A., Horuk, R., Matsushima, K., Miller, L. H., Oppenheim, J. J., & Power, C. A. (2000) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01439-x · Cited by 1,817
Self-citationThe evolutionary significance of cis-regulatory mutations
Wray, G. A. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2063 · Cited by 1,521
Ahola-Olli, A. V., Würtz, P., Havulinna, A. S., Aalto, K., Pitkänen, N., Lehtimäki, T., Kähönen, M., Lyytikäinen, L.-P., Raitoharju, E., Seppälä, I., et al. (2017) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2016.11.007 · Cited by 628
Tuning inflammation and immunity by chemokine sequestration: decoys and more
Mantovani, A., Bonecchi, R., & Locati, M. (2006) · Nature Reviews Immunology · doi:10.1038/nri1964 · Cited by 481
Gao, J.-L., Wynn, T. A., Chang, Y., Lee, E. J., Broxmeyer, H. E., Cooper, S., Tiffany, H. L., Westphal, H., Kwon-Chung, J., & Murphy, P. M. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.185.11.1959 · Cited by 441
Reich, D., Nalls, M. A., Kao, W. H. L., Akylbekova, E. L., Tandon, A., Patterson, N., Mullikin, J., Hsueh, W.-C., Cheng, C.-Y., Coresh, J., et al. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000360 · Cited by 423
Regulatory polymorphisms underlying complex disease traits.
Knight, J. C. (2005) · Journal of Molecular Medicine · doi:10.1007/s00109-004-0603-7 · Cited by 246
Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax
Gruszczyk, J., Kanjee, U., Chan, L.-J., Menant, S., Malleret, B., Lim, N. T. Y., Schmidt, C. Q., Mok, Y.-F., Lin, K.-M., Pearson, R. D., et al. (2018) · Science · doi:10.1126/science.aan1078 · Cited by 212
Choe, H., Moore, M. J., Owens, C. M., Wright, P. L., Vasilieva, N., Li, W., Singh, A. P., Shakri, R., Chitnis, C. E., & Farzan, M. (2005) · Molecular Microbiology · doi:10.1111/j.1365-2958.2004.04478.x · Cited by 148
Self-citationTournamille, C., Le Van Kim, C., Gane, P., Le Pennec, P. Y., Roubinet, F., Babinet, J., Cartron, J. P., & Colin, Y. (1998) · Blood · doi:10.1182/blood.v92.6.2147 · Cited by 137
Iwamoto, S., Omi, T., Kajii, E., & Ikemoto, S. (1995) · Blood · doi:10.1182/blood.v85.3.622.bloodjournal853622 · Cited by 126
Tournamille, C., Filipe, A., Wasniowska, K., Gane, P., Lisowska, E., Cartron, J., Colin, Y., & Le Van Kim, C. (2003) · British Journal of Haematology · doi:10.1046/j.1365-2141.2003.04533.x · Cited by 56
Velzing‐Aarts, F. V., Muskiet, F. A. J., Van Der Dijs, F. P. L., & Duits, A. J. (2002) · American Journal of Reproductive Immunology · doi:10.1034/j.1600-0897.2002.01087.x · Cited by 44
Metadata
- Authors
- Horuk, R., Chitnis, C. E., Darbonne, W. C., Colby, T. J., Rybicki, A., Hadley, T. J., & Miller, L. H.
- Venue
- Science
- Published
- 1993-08-27
- Volume
- 261
- Issue
- 5125
- Pages
- 1182-1184
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1996453015
- Cited by
- 582
- References
- 0
- FWCI
- 37.34
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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