The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
T Helper Cell Subsets in Insulin-Dependent Diabetes
Abstract
It has been proposed that the development of insulin-dependent diabetes is controlled by the T helper 1 (T H 1) versus T H 2 phenotype of autoreactive T H cells: T H 1 cells would promote diabetes, whereas T H 2 cells would actually protect from disease. This proposition was tested by establishing cultures of TH1 and TH2 cells that express an identical diabetogenic T cell receptor and comparing their ability to initiate disease in neonatal nonobese diabetic mice. T H 1-like cells actively promoted diabetes; T H 2-like cells invaded the islets but did not provoke disease—neither did they provide substantial protection.
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Cites
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Insulin-Dependent Diabetes Mellitus
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Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases
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Following a diabetogenic T cell from genesis through pathogenesis
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Self-citation
Cited by
The Role of Inflammation in Diabetes: Current Concepts and Future Perspectives
Tsalamandris, S., Antonopoulos, A. S., Oikonomou, E., Papamikroulis, G.-A., Vogiatzi, G., Papaioannou, S., Deftereos, S., & Tousoulis, D. (2019) · European Cardiology Review · doi:10.15420/ecr.2018.33.1 · Cited by 1,381
Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus
Herold, K. C., Hagopian, W., Auger, J. A., Poumian-Ruiz, E., Taylor, L., Donaldson, D., Gitelman, S. E., Harlan, D. M., Xu, D., Zivin, R. A., et al. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa012864 · Cited by 1,222
Regulation of Insulin Synthesis and Secretion and Pancreatic Beta-Cell Dysfunction in Diabetes
Fu, Z., R. Gilbert, E., & Liu, D. (2013) · Current Diabetes Reviews · doi:10.2174/157339913804143225 · Cited by 732
The Nonobese Diabetic Mouse as a Model of Autoimmune Diabetes: Immune Dysregulation Gets the NOD
Delovitch, T. L., & Singh, B. (1997) · Immunity · doi:10.1016/s1074-7613(00)80392-1 · Cited by 676
Zhang, D.-H., Cohn, L., Ray, P., Bottomly, K., & Ray, A. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.34.21597 · Cited by 665
Metadata
- Authors
- Katz, J. D., Benoist, C., & Mathis, D.
- Venue
- Science
- Published
- 1995-05-26
- Volume
- 268
- Issue
- 5214
- Pages
- 1185-1188
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2059059286
- Cited by
- 593
- References
- 55
- FWCI
- 30.01
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.