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Cited by 593

The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.

T Helper Cell Subsets in Insulin-Dependent Diabetes

Katz, Jonathan D., Benoist, Christophe, Mathis, Diane·1995·Science

Abstract

It has been proposed that the development of insulin-dependent diabetes is controlled by the T helper 1 (T H 1) versus T H 2 phenotype of autoreactive T H cells: T H 1 cells would promote diabetes, whereas T H 2 cells would actually protect from disease. This proposition was tested by establishing cultures of TH1 and TH2 cells that express an identical diabetogenic T cell receptor and comparing their ability to initiate disease in neonatal nonobese diabetic mice. T H 1-like cells actively promoted diabetes; T H 2-like cells invaded the islets but did not provoke disease—neither did they provide substantial protection.

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Metadata

Authors
Katz, J. D., Benoist, C., & Mathis, D.
Venue
Science
Published
1995-05-26
Volume
268
Issue
5214
Pages
1185-1188
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2059059286
Cited by
593
References
55
FWCI
30.01
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: T Helper Cell Subsets in Insulin-Dependent Diabetes. https://app.cochat.ai/papers/10.1126/science.7761837
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Katz, J. D., Benoist, C., & Mathis, D. (1995). T Helper Cell Subsets in Insulin-Dependent Diabetes. Science. https://doi.org/10.1126/science.7761837

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.