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Cited by 414

The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.

Solution Structure of the Epithelial Cadherin Domain Responsible for Selective Cell Adhesion

Overduin, Michael, Harvey, Timothy S., Bagby, Stefan, Tong, Kit I., Yau, Patrick, Takeichi, Masatoshi, Ikura, Mitsuhiko·1995·Science

Abstract

Cadherins are calcium-dependent cell adhesion molecules containing extracellular repeats of approximately 110 amino acids. The three-dimensional structure of the amino-terminal repeat of mouse epithelial cadherin was determined by multidimensional heteronuclear magnetic resonance spectroscopy. The calcium ion was bound by a short α helix and by loops at one end of the seven-stranded β-barrel structure. An exposed concave face is in a position to provide homophilic binding specificity and was also sensitive to calcium ligation. Unexpected structural similarities with the immunoglobulin fold suggest an evolutionary relation between calcium-dependent and calcium-independent cell adhesion molecules.

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Crossref · 10.1126/science.7824937

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Metadata

Authors
Overduin, M., Harvey, T. S., Bagby, S., Tong, K. I., Yau, P., Takeichi, M., & Ikura, M.
Venue
Science
Published
1995-01-20
Volume
267
Issue
5196
Pages
386-389
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2089714150
Cited by
414
References
26
FWCI
14.15
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Solution Structure of the Epithelial Cadherin Domain Responsible for Selective Cell Adhesion. https://app.cochat.ai/papers/10.1126/science.7824937
The paper
Overduin, M., Harvey, T. S., Bagby, S., Tong, K. I., Yau, P., Takeichi, M., & Ikura, M. (1995). Solution Structure of the Epithelial Cadherin Domain Responsible for Selective Cell Adhesion. Science. https://doi.org/10.1126/science.7824937

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.