The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Mesodermal Patterning by a Gradient of the Vertebrate Homeobox Gene goosecoid
Abstract
Amphibian mesoderm arises from the marginal zone of the early gastrula and generates various tissues such as notochord, muscle, kidney, and blood. Small changes (twofold) in the amount of microinjected messenger RNA encoding the goosecoid ( gsc ) homeodomain protein resulted in marked changes in the differentiation of mesoderm in Xenopus laevis . At least three thresholds were observed, which were sufficient to specify four mesodermal cell states. Endogenous gsc messenger RNA was expressed in the marginal zone in a graded fashion that is congruent with a role for this gene in dorso-ventral patterning of mesoderm at the early gastrula stage.
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Cites
Spatial mechanisms of gene regulation in metazoan embryos
Davidson, E. H. (1991) · Development · doi:10.1242/dev.113.1.1 · Cited by 233
Cited by
FORMATION AND FUNCTION OF SPEMANN'S ORGANIZER
Harland, R., & Gerhart, J. (1997) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.13.1.611 · Cited by 839
Frzb, a Secreted Protein Expressed in the Spemann Organizer, Binds and Inhibits Wnt-8
Wang, S., Krinks, M., Lin, K., Luyten, F. P., & Moos, M. (1997) · Cell · doi:10.1016/s0092-8674(00)81922-4 · Cited by 518
Onichtchouk, D., Gawantka, V., Dosch, R., Delius, H., Hirschfeld, K., Blumenstock, C., & Niehrs, C. (1996) · Development · doi:10.1242/dev.122.10.3045 · Cited by 270
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Metadata
- Authors
- Niehrs, C., Steinbeisser, H., & De Robertis, E. M.
- Venue
- Science
- Published
- 1994-02-11
- Volume
- 263
- Issue
- 5148
- Pages
- 817-820
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2014048648
- Cited by
- 166
- References
- 1
- FWCI
- 7.48
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Mesodermal Patterning by a Gradient of the Vertebrate Homeobox Gene goosecoid. https://app.cochat.ai/papers/10.1126/science.7905664
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- Niehrs, C., Steinbeisser, H., & De Robertis, E. M. (1994). Mesodermal Patterning by a Gradient of the Vertebrate Homeobox Gene goosecoid. Science. https://doi.org/10.1126/science.7905664
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
