The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
DNA Sequence from Cretaceous Period Bone Fragments
Abstract
DNA was extracted from 80-million-year-old bone fragments found in strata of the Upper Cretaceous Blackhawk Formation in the roof of an underground coal mine in eastern Utah. This DNA was used as the template in a polymerase chain reaction that amplified and sequenced a portion of the gene encoding mitochondrial cytochrome b. These sequences differ from all other cytochrome b sequences investigated, including those in the GenBank and European Molecular Biology Laboratory databases. DNA isolated from these bone fragments and the resulting gene sequences demonstrate that small fragments of DNA may survive in bone for millions of years.
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Citations
Cites
Instability and decay of the primary structure of DNA
Lindahl, T. (1993) · Nature · doi:10.1038/362709a0 · Cited by 5,679
Cited by
Crooks, R. M., Zhao, M., Sun, L., Chechik, V., & Yeung, L. K. (2001) · Accounts of Chemical Research · doi:10.1021/ar000110a · Cited by 2,115
Environmental DNA – An emerging tool in conservation for monitoring past and present biodiversity
Thomsen, P. F., & Willerslev, E. (2015) · Biological Conservation · doi:10.1016/j.biocon.2014.11.019 · Cited by 2,082
Genetic analyses from ancient DNA
Pääbo, S., Poinar, H., Serre, D., Jaenicke-Després, V., Hebler, J., Rohland, N., Kuch, M., Krause, J., Vigilant, L., & Hofreiter, M. (2004) · Annual Review of Genetics · doi:10.1146/annurev.genet.37.110801.143214 · Cited by 1,333
Contamination in Low Microbial Biomass Microbiome Studies: Issues and Recommendations
Eisenhofer, R., Minich, J. J., Marotz, C., Cooper, A., Knight, R., & Weyrich, L. S. (2019) · Trends in Microbiology · doi:10.1016/j.tim.2018.11.003 · Cited by 1,146
Willerslev, E., & Cooper, A. (2005) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2004.2813 · Cited by 712
Metadata
- Authors
- Woodward, S. R., Weyand, N. J., & Bunnell, M.
- Venue
- Science
- Published
- 1994-11-18
- Volume
- 266
- Issue
- 5188
- Pages
- 1229-1232
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2062692373
- Cited by
- 311
- References
- 1
- FWCI
- 18.46
- Type
- journal article
- Language
- en
- Open access
- closed
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- Woodward, S. R., Weyand, N. J., & Bunnell, M. (1994). DNA Sequence from Cretaceous Period Bone Fragments. Science. https://doi.org/10.1126/science.7973705
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
