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Cited by 358

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Molecular Dynamics Simulations of a Lipid Bilayer and of Hexadecane: An Investigation of Membrane Fluidity

Venable, Richard M., Zhang, Yuhong, Hardy, Barry J., Pastor, Richard W.·1993·Science

Abstract

Molecular dynamics simulations of a fluid-phase dipalmitoyl phosphatidylcholine lipid bilayer in water and of neat hexadecane are reported and compared with nuclear magnetic resonance spin-lattice relaxation and quasi-elastic neutron scattering data. On the 100-picosecond time scale of the present simulations, there is effectively no difference in the reorientational dynamics of the carbons in the membrane interior and in pure hexadecane. Given that the calculated fast reorientational correlation times and the "microscopic" lateral diffusion of the lipids show excellent agreement with the experimental results, it is concluded that the apparently high viscosity of the membrane is more closely related to molecular interactions on the surface rather than in the interior.

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Metadata

Authors
Venable, R. M., Zhang, Y., Hardy, B. J., & Pastor, R. W.
Venue
Science
Published
1993-10-08
Volume
262
Issue
5131
Pages
223-226
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2005030208
Cited by
358
References
1
FWCI
6.99
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Molecular Dynamics Simulations of a Lipid Bilayer and of Hexadecane: An Investigation of Membrane Fluidity. https://app.cochat.ai/papers/10.1126/science.8211140
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Venable, R. M., Zhang, Y., Hardy, B. J., & Pastor, R. W. (1993). Molecular Dynamics Simulations of a Lipid Bilayer and of Hexadecane: An Investigation of Membrane Fluidity. Science. https://doi.org/10.1126/science.8211140

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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