The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
On the Crawling of Animal Cells
Abstract
Cells crawl in response to external stimuli by extending and remodeling peripheral elastic lamellae in the direction of locomotion. The remodeling requires vectorial assembly of actin subunits into linear polymers at the lamella's leading edge and the crosslinking of the filaments by bifunctional gelation proteins. The disassembly of the crosslinked filaments into short fragments or monomeric subunits away from the leading edge supplies components for the actin assembly reactions that drive protrusion. Cellular proteins that respond to lipid and ionic signals elicited by sensory cues escort actin through this cycle in which filaments are assembled, crosslinked, and disassembled. One class of myosin molecules may contribute to crawling by guiding sensory receptors to the cell surface, and another class may contribute by imposing contractile forces on actin networks in the lamellae.
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Cites
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Control of nonmuscle myosins by phosphorylation
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Novel form of growth cone motility involving site-directed actin filament assembly
Forscher, P., Lin, C. H., & Thompson, C. (1992) · Nature · doi:10.1038/357515a0 · Cited by 153
Cited by
Cell Migration: A Physically Integrated Molecular Process
Lauffenburger, D. A., & Horwitz, A. F. (1996) · Cell · doi:10.1016/s0092-8674(00)81280-5 · Cited by 3,915
Functional significance of cell volume regulatory mechanisms
LANG, F., BUSCH, G. L., RITTER, M., VÖLKL, H., WALDEGGER, S., GULBINS, E., & HÄUSSINGER, D. (1998) · Physiological Reviews · doi:10.1152/physrev.1998.78.1.247 · Cited by 1,891
Rho Family GTPases Bind to Phosphoinositide Kinases
Tolias, K. F., Cantley, L. C., & Carpenter, C. L. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.30.17656 · Cited by 466
Iba1 Is an Actin-Cross-Linking Protein in Macrophages/Microglia
Sasaki, Y., Ohsawa, K., Kanazawa, H., Kohsaka, S., & Imai, Y. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.5388 · Cited by 373
Intracellular signaling in M‐CSF‐induced microglia activation: Role of Iba1
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Metadata
- Authors
- Stossel, T. P.
- Venue
- Science
- Published
- 1993-05-21
- Volume
- 260
- Issue
- 5111
- Pages
- 1086-1094
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2030463167
- Cited by
- 1,011
- References
- 4
- FWCI
- 34.15
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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