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Structure of a Molluscan Cardioexcitatory Neuropeptide
Abstract
A cardioexcitatory substance from ganglia of the clam Macrocallista nimbosa, formerly designated peak C, is the tetrapeptide amide Phe-Met-Arg-Phe-NH 2 . Its structure was determined by the combined use of Edman dansyl degradation and tryptic digestion. The structure was confirmed by synthesis. This neuropeptide is active at about 10 -8 M when assayed on molluscan muscle.
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Cited by
Yang, H. Y., Fratta, W., Majane, E. A., & Costa, E. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.22.7757 · Cited by 608
Cloning of the amiloride-sensitive FMRFamide peptide-gated sodium channel
Lingueglia, E., Champigny, G., Lazdunski, M., & Barbry, P. (1995) · Nature · doi:10.1038/378730a0 · Cited by 391
Function of the ventrolateral medulla in the control of the circulation
Ciriello, J., Caverson, M. M., & Polosa, C. (1986) · Brain Research Reviews · doi:10.1016/0165-0173(86)90005-6 · Cited by 332
Bentley, G. E., Perfito, N., Ukena, K., Tsutsui, K., & Wingfield, J. C. (2003) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2003.01062.x · Cited by 276
Cnidarians and the evolutionary origin of the nervous system
Watanabe, H., Fujisawa, T., & Holstein, T. W. (2009) · Development, Growth & Differentiation · doi:10.1111/j.1440-169x.2009.01103.x · Cited by 206
Metadata
- Authors
- Price, D. A., & Greenberg, M. J.
- Venue
- Science
- Published
- 1977-08-12
- Volume
- 197
- Issue
- 4304
- Pages
- 670-671
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2043129540
- Cited by
- 1,061
- References
- 0
- FWCI
- 1.75
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
