The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency
Open accessAbstract
A genetic cause for severe influenza: Although chicken soup and plenty of rest get most kids through an influenza virus infection, some require hospitalization. Ciancanelli et al. report on one child who suffered severely from influenza because of null mutations in the gene for transcription factor IRF7. Cells isolated from this patient could not make enough secreted antiviral proteins, called interferons, to halt viral replication. The requirement for IRF7 seems quite specific, because this patient recovers normally from other common childhood viral infections. Science , this issue p. 448
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Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
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Metadata
- Authors
- Ciancanelli, M. J., Huang, S. X. L., Luthra, P., Garner, H., Itan, Y., Volpi, S., Lafaille, F. G., Trouillet, C., Schmolke, M., Albrecht, R. A., Israelsson, E., Lim, H. K., Casadio, M., Hermesh, T., Lorenzo, L., Leung, L. W., Pedergnana, V., Boisson, B., Okada, S., Picard, C., Ringuier, B., Troussier, F., Chaussabel, D., Abel, L., Pellier, I., Notarangelo, L. D., García-Sastre, A., Basler, C. F., Geissmann, F., Zhang, S.-Y., Snoeck, H.-W., & Casanova, J.-L.
- Venue
- Science
- Published
- 2015-04-24
- Volume
- 348
- Issue
- 6233
- Pages
- 448-453
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1977853360
- Cited by
- 476
- References
- 47
- FWCI
- 17.59
- Type
- journal article
- Language
- en
- Open access
- green
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- The paper
- Ciancanelli, M. J., Huang, S. X. L., Luthra, P., Garner, H., Itan, Y., Volpi, S., Lafaille, F. G., Trouillet, C., Schmolke, M., Albrecht, R. A., Israelsson, E., Lim, H. K., Casadio, M., Hermesh, T., Lorenzo, L., Leung, L. W., Pedergnana, V., Boisson, B., Okada, S., . . . Casanova, J.-L. (2015). Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency. Science. https://doi.org/10.1126/science.aaa1578
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
