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Cited by 395

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

The complete structure of the 55 S mammalian mitochondrial ribosome

Open access
Greber, Basil J., Bieri, Philipp, Leibundgut, Marc, Leitner, Alexander, Aebersold, Ruedi, Boehringer, Daniel, Ban, Nenad·2015·Science

Abstract

Resolving whole mitoribosomes: Mitochondria probably evolved from a prokaryotic cell living within a proto-eukaryotic cell. Consequently, mitochondria have lost much of their genomic DNA, except for a few genes that require highly divergent mitoribosomes for protein translation. Greber et al. and Amunts et al. have used cryo–electron microscopy to uncover the structure of this complex (see the Perspective by Beckmann and Hermann) and reveal an unusual mRNA binding channel. The structure supplies clues for how aminoglycoside antibiotics might inhibit mitoribosomes and how mutations in mitoribosomes might cause human disease. Science , this issue p. 303 , p. 288 ; see also A. Amunts et al., Science , 3 April, p. 95

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Crossref · 10.1126/science.aaa3872

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Metadata

Authors
Greber, B. J., Bieri, P., Leibundgut, M., Leitner, A., Aebersold, R., Boehringer, D., & Ban, N.
Venue
Science
Published
2015-04-17
Volume
348
Issue
6232
Pages
303-308
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2083157472
Cited by
395
References
6
FWCI
19.30
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The complete structure of the 55 S mammalian mitochondrial ribosome. https://app.cochat.ai/papers/10.1126/science.aaa3872
The paper
Greber, B. J., Bieri, P., Leibundgut, M., Leitner, A., Aebersold, R., Boehringer, D., & Ban, N. (2015). The complete structure of the 55 S mammalian mitochondrial ribosome. Science. https://doi.org/10.1126/science.aaa3872

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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