The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring

Choi, Gloria B., Yim, Yeong S., Wong, Helen, Kim, Sangdoo, Kim, Hyunju, Kim, Sangwon V., Hoeffer, Charles A., Littman, Dan R., Huh, Jun R.·2016·Science

DOI 10.1126/science.aad0314

Cited by (1,000)

Items 701–800 of 1,000

P2Y2 receptor mediates dying cell removal via inflammatory activated microglia
Izumi Hide, Hiroko Shiraki, Akihiro Masuda, Takuya Maeda, Mayuka Kumagai, Nao Kunishige, Yuhki Yanase, Kana Harada, Shigeru Tanaka, Norio Sakai · 2023 · Journal of Pharmacological Sciences
Network Structure Analysis Identifying Key Genes of Autism and Its Mechanism
Yanhui Wang, Yanming Kou, Dazhi Meng · 2020 · Computational and Mathematical Methods in Medicine
Effects of immunization with heat-killed Mycobacterium vaccae on autism spectrum disorder-like behavior and epileptogenesis in a rat model of comorbid autism and epilepsy
Zachariah Z. Smith, Rebecca A. Kubiak, Mathew R. Arnold, Kelsey M. Loupy, Jeremy A. Taylor, Taylor G. Crist, Allison E. Bernier, Heather M. D’Angelo, Jared D. Heinze, Christopher A. Lowry et al. · 2020 · Brain Behavior and Immunity
Tracking the fate and migration of cells in live animals with cell-cycle indicators and photoconvertible proteins
Michio Tomura, Ryoyo Ikebuchi, Taiki Moriya, Yutaka Kusumoto · 2021 · Journal of Neuroscience Methods
Maternal Immune Activation and Interleukin 17A in the Pathogenesis of Autistic Spectrum Disorder and Why It Matters in the COVID-19 Era
Michael Carter, Sophie Casey, Gerard W. O’Keeffe, Louise Gibson, Louise Gallagher, Deirdre M. Murray · 2022 · Frontiers in Psychiatry
Methylmercury chloride exposure exacerbates existing neurobehavioral and immune dysfunctions in the BTBR T+ Itpr3tf/J mouse model of autism
Haneen A. Al‐Mazroua, Ahmed Nadeem, Mushtaq Ahmad Ansari, Sabry Mohamed Attia, Thamer H. Albekairi, Saleh A. Bakheet, Abdulelah F. Alobaidi, Khaled A. Alhosaini, Saleh Abdullah Alqarni, Khalid E. Ibrahim et al. · 2022 · Immunology Letters
Overview of prospects for inflammation pathways in autism spectrum disorders
Hugo Turbé, Louis Waeckel, Benoît Déchelotte · 2019 · L Encéphale
Effects of gastrointestinal symptoms on the efficacy of washed microbiota transplantation in patients with autism
Hu, Dong-Xia, Lu, Cai-Mei, Si, Xin-Yu, Wu, Qing-Ting, Wu, Li-Hao, Zhong, Hao-Jie, He, Xing-Xiang · 2025 · Frontiers in Pediatrics
Meningeal lymphatics as a therapeutic target for neurodegenerative disorders
Yijia Feng, Shengya Wang, Huwei Xia, Xinyi Jiang, Mingming Wu, Sipei Pan, Weihong Song · 2025 · Translational Neurodegeneration
WDFY3 mutation alters laminar position and morphology of cortical neurons
Zachary A. Schaaf, Lyvin Tat, Noemi Cannizzaro, Alexios A. Panoutsopoulos, Ralph Green, Thomas Rülicke, Simon Hippenmeyer, Konstantinos S. Zarbalis · 2022 · Molecular Autism
Prenatal methamphetamine exposure causes dysfunction in glucose metabolism and low birthweight
Miyuki Doi, Nanako Nakama, Takuya Sumi, Noriyoshi Usui, Shoichi Shimada · 2022 · Frontiers in Endocrinology
Maternal Th17 Profile after Zika Virus Infection Is Involved in Congenital Zika Syndrome Development in Children
Eder Magalhães Silva Fialho, Emanoel M. Veras, Caroline M. de Jesus, Lillian Nunes Gomes, Ricardo Khouri, Patrícia S. Sousa, Marizélia Rodrigues Costa Ribeiro, Rosângela Fernandes Lucena Batista, Luciana Cavalcante Costa, Flávia Raquel Fernandes do Nascimento et al. · 2023 · Viruses
Does the kynurenine pathway play a pathogenic role in autism spectrum disorder?
Danielle Santana‐Coelho · 2024 · Brain Behavior & Immunity - Health
Prenatal and early childhood infections requiring hospitalization and risk of neurodevelopmental disorders in offspring: a population-based birth cohort study in Taiwan
Mei‐Chen Lin, Yi‐Jiun Pan, Chi‐Shin Wu, Chia‐Lin Liu, Pei‐Chun Chen, Wesley Kurt Thompson, Chun Chieh Fan, Shi‐Heng Wang · 2024 · Molecular Psychiatry
The roles of immune factors in neurodevelopment
Chong Wang, Tingting He, Jie Qin, Jianwei Jiao, Fen Ji · 2025 · Frontiers in Cellular Neuroscience
Upregulation of enzymatic antioxidants in CD4+ T cells of autistic children
Ahmed Nadeem, Sheikh F. Ahmad, Naif Obaid Al-Harbi, Abdullah F. Alasmari, Laila Yousef AL-Ayadhi, Fawaz F. Alasmari, Khalid E. Ibrahim, Sabry Mohamed Attia, Saleh A. Bakheet · 2020 · Biochimie
Dietary Cholesterol Metabolite Regulation of Tissue Immune Cell Development and Function
Michela Frascoli, Andrea Reboldi, Joonsoo Kang · 2022 · The Journal of Immunology
Social and psychological adversity are associated with distinct mother and infant gut microbiome variations
Barbara B. Warner, Bruce A. Rosa, I. Malick Ndao, Phillip I. Tarr, J. Philip Miller, Sarah K. England, Joan L. Luby, Cynthia E. Rogers, Carla M. Hall-Moore, Renay E. Bryant et al. · 2023 · Nature Communications
Prenatal Allergic Inflammation in Rats Confers Sex-Specific Alterations to Oxytocin and Vasopressin Innervation in Social Brain Regions
Michaela R. Breach, Habib E. Akouri, Sophia Costantine, Claire M. Dodson, Nolan McGovern, Kathryn M. Lenz · 2023 · Hormones and Behavior
Cytokine responses to SARS-COV2 infection in mother-infant dyads: a systematic review and meta-analysis
Samhita Jain, Isabel Elaine Allen, Dongli Song, Xianhua Piao · 2023 · Frontiers in Pediatrics
Osteocalcin of maternal and embryonic origins synergize to establish homeostasis in offspring
Danilo Correa Pinto Junior, Isabella Canal Delgado, Haiyang Yang, Alisson Clemenceau, André Corvelo, Giuseppe Narzisi, Rajeeva Musunuri, Julian Meyer Berger, Lauren Hendricks, Kazuya Tokumura et al. · 2024 · EMBO Reports
Brain, Immunity, Gut: “BIG” Links between Pregnancy and Autism
Myka L. Estes, A. Kimberley McAllister · 2017 · Immunity
A Destruction Model of the Vascular and Lymphatic Systems in the Emergence of Psychiatric Symptoms
Kohei Segawa, Yukari Blumenthal, Yuki Yamawaki, Gen Ohtsuki · 2021 · Biology
Dataset describing maternal prenatal restraint stress effects on immune factors in mice
Serena B. Gumusoglu, Sara V. Maurer, Hanna Elizabeth Stevens · 2022 · Data in Brief
Glucocorticoid receptor dysregulation underlies 5-HT2AR-dependent synaptic and behavioral deficits in a mouse neurodevelopmental disorder model
Justin M. Saunders, Carolina Muguruza, Salvador Sierra, José L. Moreno, Luis Felipe Callado, J. Javier Meana, Patrick M. Beardsley, Javier González‐Maeso · 2022 · Journal of Biological Chemistry
Maternal obstructive sleep apnea aggravates metabolic dysfunction-associated fatty liver disease via HMGB1-TLR4 signaling-mediated endoplasmic reticulum stress in male offspring rats
Ruhua Wang, Wei Feng, Yan Wang, Yonghong Jiang, Yiguang Lin, Xueqing Chen · 2023 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Single exposure to anesthesia/surgery in neonatal mice induces cognitive impairment in young adult mice
Songhua Zhou, Xiaoyu Cui, Jie Chen, Manli Luo, Wen Ouyang, Jianbin Tong, Zhongcong Xie, Yuan Le · 2024 · Free Radical Biology and Medicine
Bidirectional interaction between IL and 17A/IL-17RA pathway dysregulation and α-synuclein in the pathogenesis of Parkinson’s disease
Yu‐Chen Yan, Lu Su, W Zhao, Yun Fan, James B. Koprich, Bao‐Guo Xiao, Bin Song, Jian Wang, Wenbo Yu · 2024 · Brain Behavior and Immunity
Maternal immune activation induces neurodevelopmental impairments of adult offspring through alterations in tryptophane-kynurenine pathway in the placenta
Masaya Hasegawa, Moe Niijima, Kazuo Kunisawa, Tomoaki Teshigawara, Hisayoshi Kubota, Suwako Fujigaki, Hidetsugu Fujigaki, Yasuko Yamamoto, Hyoung‐Chun Kim, Kuniaki Saito et al. · 2024 · Biochemical and Biophysical Research Communications
SARS-CoV-2 infection elucidates features of pregnancy-specific immunity
Dong Sun Oh, Eunha Kim, Guangqing Lu, Rachelly Normand, Lydia L. Shook, Amanda E. Lyall, Olyvia J. Jasset, Stepan Demidkin, Emily Gilbert, Joon Mee Kim et al. · 2024 · Cell Reports
Air pollution: an emerging risk factor for autism spectrum disorder
Shashank Kumar Ojha, Haitham Amal · 2024 · Brain medicine :
Maternal immune activation imprints translational dysregulation and differential MAP2 phosphorylation in descendant neural stem cells
Sandra M. Martín-Guerrero, María Martín‐Estebané, Antonio Jesús Lara Ordóñez, Miguel Cánovas, David Martín‐Oliva, Javier González‐Maeso, Pedro R. Cutillas, Juan F. López‐Giménez · 2025 · Molecular Psychiatry
Nod2 deficiency exacerbates schizophrenia-related alterations in offspring of maternal immune activation in a sex-dependent manner
Fengjie Gao, Chuyao Wang, Zhen Cao, Xinyu Zhang, Wenyu Xi, Yixin Liu, Xianyan Zhan, Min Jia, Ningzhi Gou, Lu Yu et al. · 2025 · Brain Behavior and Immunity
Relationship between PFAS and attention-deficit/hyperactivity disorder or autism spectrum disorder: Epidemiological and experimental evidence
Keyue Wu, Aidi Tang, Xing Zhang, Shun Zhou, Nana Wu, Junyan Tao, Yun Chen, Guanghong Yang, Hao Zhou, Mingdan You · 2025 · Ecotoxicology and Environmental Safety
The Role of Prenatal Microglial Activation and Its Sex Differences in the Development of Neuropsychiatric Disorders and Neurodegenerative Diseases
Alexander Sergeevich Lyamtsev, Alexandra Vladislavovna Sentyabreva, Anna Mikhailovna Kosyreva · 2025 · International Journal of Molecular Sciences
Integrative multi-omics reveals microbial genomic variants driving altered host-microbe interactions in autism spectrum disorder
Wanning Chen, Xinjun Wang, Ruixin Zhu, Wenxing Gao, Liwen Tao, Rong Yang, Qing Wei, Yiming Zhang, Yujiao Gong, Hui Zhong et al. · 2025 · Cell Reports Medicine
Reversing neural circuit and behavior deficit in mice exposed to maternal inflammation by Zika virus
Li Ma, Jing Wang, Jianlong Ge, Yuan Wang, Wei Zhang, Yuanning Du, Jun Luo, Yangping Li, Feng Wang, Guoping Fan et al. · 2021 · EMBO Reports
Interleukin-17A stimulation induces alterations in Microglial microRNA expression profiles
Yukako Iitani, Rika Miki, Kenji Imai, Kazuya Fuma, Takafumi Ushida, Sho Tano, Kosuke Yoshida, Akira Yokoi, Hiroaki Kajiyama, Tomomi Kotani · 2023 · Pediatric Research
Gut Microbiome and Sex Bias in Autism Spectrum Disorders
Afaf K El-Ansary, Ramesa Shafi Bhat, Naima Zayed · 2020 · Current Behavioral Neuroscience Reports
Relationship between T cells and microbiota in health and disease
Takahiro Kageyama, Takashi Matsuo, Reina Kurakake, Teruyuki Sano · 2020 · Progress in molecular biology and translational science
The Microbiome-Gut-Brain Axis: A New Window to View the Impact of Prenatal Stress on Early Neurodevelopment
Naama Rotem‐Kohavi, James Keane, Gerard A. Clarke, Timothy G. Dinan, John F. Cryan, Fergus P. McCarthy, Tim F. Oberlander, Siobhain M. O’Mahony · 2021 · Springer eBooks
Identifying Rare Genetic Variants of Immune Mediators as Risk Factors for Autism Spectrum Disorder
Chunquan Cai, Zhaoqing Yin, Aiping Liu, Hui Wang, Shujuan Zeng, Zhangxing Wang, Huixian Qiu, Shijun Li, Jiaxiu Zhou, Mingbang Wang · 2022 · Genes
Endogenous Interleukin-17a Contributes to Normal Spatial Memory Retention but Does Not Affect Early Behavioral or Neuropathological Outcomes after Experimental Traumatic Brain Injury
Dennis W. Simon, Itay Raphael, Kendall M. Johnson, C. Edward Dixon, Vincent Vagni, Keri L. Janesko‐Feldman, Patrick Michael Kochanek, Hülya Bayır, Robert S. B. Clark, Mandy J. McGeachy · 2022 · Neurotrauma Reports
Cadmium Exposure Is Associated with Behavioral Deficits and Neuroimmune Dysfunction in BTBR T+ Itpr3tf/J Mice
Mohammed Mufadhe Alanazi, Mushtaq Ahmad Ansari, Ahmed Nadeem, Sabry Mohamed Attia, Saleh A. Bakheet, Haneen A. Al‐Mazroua, Abdullah A. Aldossari, Mohammed M. Almutairi, Thamer H. Albekairi, Marwa H. Hussein et al. · 2023 · International Journal of Molecular Sciences
Therapeutic potential of CBD in Autism Spectrum Disorder
João Francisco Cordeiro Pedrazzi, Lucas Hassib, Frederico Rogério Ferreira, Jaime E. C. Hallak, Elaine Del-Bel, José Alexandre S. Crippa · 2024 · International review of neurobiology
Mum's bacteria linked to baby's behaviour
Craig M. Powell · 2017 · Nature
All roads lead to inflammation: Is maternal immune activation a common culprit behind environmental factors impacting offspring neural control of breathing?
Andrew O. Knutson, Jyoti J. Watters · 2019 · Respiratory Physiology & Neurobiology
Microglia and Microbiome-Gut-Brain Axis
Adriano Maia Chaves Filho, Nayana Soares Gomes, Deniele Bezerra Lós, Isabel Bessa Leite, Marie‐Ève Tremblay, Danielle S. Macêdo · 2024 · Advances in neurobiology
Crosstalk Between Mitochondrial DNA and Immune Response: Focus on Autism Spectrum Disorder
Wenxuan Qu, Ge Yan, Yajuan Du, Xinyang Zhou, Chutian Huang, Bei Li, Junmei Zhou, Qian Li · 2024 · Molecular Neurobiology
Prenatal inflammation impairs early CD11c-positive microglia induction and delays myelination in neurodevelopmental disorders
Kazuya Fuma, Yukako Iitani, Kenji Imai, Takafumi Ushida, Sho Tano, Kosuke Yoshida, Akira Yokoi, Rika Miki, Hiroyuki Kidokoro, Yoshiaki Sato et al. · 2025 · Communications Biology
IFN-γ signaling links ventriculomegaly to choroid plexus and ependyma dysfunction following maternal immune activation
Yuqin Sun, Xinxin Huang, Wei Guo, Chen Hong, Juan Ji, Xi-Yue Zhang, Jin Yang, Gang Hu, Xiu‐Lan Sun · 2025 · Journal of Neuroinflammation
The role of interleukin-17 in neurological disorders
Seung Eun Park, Ana Flávia Fernandes Ferreira, Hyeokbin Kwon, Jeongwoo Yu, Leila Diniz, Henning Ulrich, Luiz R.G. Britto, Eunha Kim · 2025 · Animal Cells and Systems
Advancing precision diagnosis in autism: Insights from large-scale genomic studies
Soo-Whee Kim, Joon‐Yong An · 2025 · Molecules and Cells
The role of maternal infections in neurodevelopmental psychiatric disorders: focus on the P2X7/NLRP3/IL-1β signalling pathway
Dorottya Szabó, Lilla Otrokocsi, Beáta Sperlágh · 2025 · Journal of Neuroinflammation
Influenza A virus infection during pregnancy increases transfer of maternal bloodborne molecules to fetal tissues
Rafael Gonzalez-Ricon, Ashley M. Otero, Izan Chalen, Jeffrey N. Savas, Shakirat Adeola Adetunji, Adrienne M. Antonson · 2025 · Brain Behavior and Immunity
Is it possible to prevent excessive synaptic pruning in schizophrenia? Possibilities and limitations
Agnieszka Pawlak, Jakub Stefanowicz, Zofia Kotkowska, Agata Gabryelska, Marcin Sochal, Filip Napieraj, Magdalena Kotlicka‐Antczak, Dominik Strzelecki · 2025 · Frontiers in Synaptic Neuroscience
Cross-generational mechanisms of maternal gut microbiota in modulating offspring autism spectrum disorder risk: from the gut-brain axis to translational challenges in precision interventions
Dashuang Zhang, Min Zhou, Yudan Qiu, Hongxia Xu, Hanmin Liu, Yang Liu, Liang Xie · 2025 · Frontiers in Aging Neuroscience
Construction of an immune-related ceRNA network to screen for potential diagnostic markers for autism spectrum disorder
Jingjing Sun, Bo Chen, Tao Yu · 2022 · Frontiers in Genetics
Pluripotent stem cell-derived neural progenitor cells can be used to model effects of IL-6 on human neurodevelopment
Kseniia Sarieva, Felix Hildebrand, Theresa Kagermeier, Zeynep Yentür, Katharina Becker, Simone Mayer · 2023 · Disease Models & Mechanisms
Changes in ADAR RNA editing patterns in CMV and ZIKV congenital infections
Benjamin D Wales-McGrath, Heather Mercer, Helen Piontkivska · 2023 · BMC Genomics
Shank3 deficiency elicits autistic-like behaviors by activating p38α in hypothalamic AgRP neurons
Shanshan Wu, Jing Wang, Zicheng Zhang, Xinchen Jin, Yang Xu, Youwen Si, Yixiao Liang, Yueping Ge, Huidong Zhan, Li peng et al. · 2024 · Molecular Autism
Resveratrol regulates Thoc5 to improve maternal immune activation-induced autism-like behaviors in adult mouse offspring
Xin Zeng, Linlin Fan, Mengyue Li, Qian Qin, Xiuming Pang, Shanyi Shi, Danyang Zheng, Yutong Jiang, Han Wang, Lijie Wu et al. · 2024 · The Journal of Nutritional Biochemistry
The neurobiological mechanisms underlying the effects of exercise interventions in autistic individuals
Genghong Tu, Nan Jiang, Weizhong Chen, Lining Liu, Min Hu, Bagen Liao · 2024 · Reviews in the Neurosciences
Immunological Processes in Schizophrenia Pathology: Potential Biomarkers?
Tina Notter · 2018 · Current topics in behavioral neurosciences
Immunology and microbiology: how do they affect social cognition and emotion recognition?
Weronika Barcik, Giulia Chiacchierini, Zisis Bimpisidis, Francesco Papaleo · 2021 · Current Opinion in Immunology
Maternal multiple sclerosis is not a risk factor for neurodevelopmental disorders in offspring
Alessandra Carta, Ignazio Roberto Zarbo, Chiara Scoppola, Giulia Pisuttu, Marta Conti, Maria Clotilde Melis, Federica De Martino, Antonella Serra, Maria Angela Biancu, Franca Rosa Guerini et al. · 2021 · Multiple Sclerosis Journal - Experimental Translational and Clinical
Does Far-Infrared Therapy Improve Peritoneal Function and Reduce Recurrent Peritonitis in Peritoneal Dialysis Patients?
Yuanmay Chang, Jui-Ting Chang, Mei-Yi Lee, Mei-Zen Huang, Yann-Fen Chao, Yung‐Luen Shih, Yao-Rong Hwang · 2022 · Journal of Clinical Medicine
Stress-induced despair behavior develops independently of the Ahr-RORγt axis in CD4 + cells
Courtney R. Rivet-Noor, Andrea R. Merchak, Sihan Li, Rebecca M. Beiter, Sangwoo Lee, Jalon Aaron Thomas, Anthony Fernández-Castañeda, Jung‐Bum Shin, Alban Gaultier · 2022 · Scientific Reports
Intersections of the microbiome and early neurodevelopment
Helen E. Vuong · 2022 · International review of neurobiology
The Use of Optical Coherence Tomography and Electrophysiological Tests in the Early Diagnosis of Inflammatory Changes in the CNS in children with ASD—A Review of Contemporary Literature
Monika Modrzejewska, Wiktoria Bosy-Gąsior · 2023 · International Journal of Environmental Research and Public Health
MIA mice exhibit enteric nerve defects and are more susceptible to dextran sulfate sodium-induced colitis
Qian Li, Shuang Li, Yiwei Yao, Zhongxiang Ma, Chutian Huang · 2023 · Brain Behavior and Immunity
Modulation of vagal activity may help reduce neurodevelopmental damage in the offspring of mothers with pre-eclampsia
Eric Alonso Abarca-Castro, Ana Karen Talavera-Peña, José Javier Reyes Lagos, Enrique Becerril‐Villanueva, Gilberto Pérez‐Sánchez, Francisco R. de la Peña, José Luis Maldonado-García, Lenin Pavón · 2023 · Frontiers in Immunology
A choroid plexus apocrine secretion mechanism shapes CSF proteome and embryonic brain development
Ya’el Courtney, Joshua P. Head, Elizabeth D. Yimer, Neil Dani, Frederick B. Shipley, Towia A. Libermann, Maria K. Lehtinen · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
Prdm16-dependent antigen-presenting cells induce tolerance to intestinal antigens
Liuhui Fu, Rabi Upadhyay, Maria V. Pokrovskii, Francis M. Chen, Gabriela Romero‐Meza, Adam D. Griesemer, Dan R. Littman · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
Hierarchical cortical transcriptome disorganization in autism
Lombardo, Michael V., Courchesne, Eric, Lewis, Nathan E., Pramparo, Tiziano · 2016
Effects of RORγt overexpression on the murine central nervous system
Tetsuya Sasaki, Rei Nagata, Satoru Takahashi, Yosuke Takei · 2021 · Neuropsychopharmacology Reports
Detection of abnormal behaviors in prenatal Poly(I:C) exposed mice in a group‐rearing environment
Munekazu Komada, Niina Kiriyama, Rei Sugiyama, Kazuma Harada, Norihito Kawashita · 2024 · Congenital Anomalies
A meta-analysis of sex differences in neonatal rodent ultrasonic vocalizations and the implication for the preclinical maternal immune activation model
Alison M. Randell, Stephanie Salia, Lucas F. Fowler, Toe Aung, David Andrew Puts, Ashlyn Swift‐Gallant · 2025 · Biology of Sex Differences
Maternal immune activation elicits rapid and sex-dependent changes in gene expression and vascular dysfunction in the rat placenta
Erin Biggar, Ruth E Thomas, Megan L Lave, Gargi Jaju Bhattad, Nagalingam Rajakumar, Stephen James Renaud · 2025 · Placenta
Neuroimmune and behavioral changes elicited by maternal immune activation in mice are ameliorated by early postnatal immune stimulation
Lourdes K. Davis, Louise Madeleine Ince, Sriya Gullapalli, Laura K. Fonken · 2025 · Brain Behavior and Immunity
Lacticaseibacillus rhamnosus GR-1 prevents autism-like behaviors by reshaping the maternal and offspring microbiome
Ruili Yang, Yi Xu, Jinchun Xu, Chengqing Huang, Feng Zhu, Tian Wang, Rui Kong, Jie Xiao, Biao He, Xiaozhen Gu et al. · 2025 · npj Biofilms and Microbiomes
Maladaptive immunity to the microbiota promotes neuronal hyperinnervation and itch via IL-17A
Jeremie Delaleu, Verónica Liliana Burstein, Eduard Ansaldo, Ignacio Beccacece, M. Nagai, Nicolas Jean Bouladoux, Dan Corral, Andrea Muñoz Zamora, Adelle Ayash, Margery G. Smelkinson et al. · 2025 · Proceedings of the National Academy of Sciences
Gut microbiota and its metabolism in autism spectrum disorder: from pathogenesis to therapy
Wanping Bu, Zhichuan Chen, Bo Liu, Xiaokang Jia · 2026 · Frontiers in Cellular and Infection Microbiology
Microbiota-Immune System Interactions in Human Neurological Disorders
Qin Huang, Yu Fang, Di Liao, Jian Xia · 2020 · CNS & Neurological Disorders - Drug Targets
Sex-Differential Gene Expression in Developing Human Cortex and Its Intersection With Autism Risk Pathways
Lee T. Kissel, Sirisha Pochareddy, Joon‐Yong An, Nenad Šestan, Stephan Sanders, Xuran Wang, Donna M. Werling · 2024 · Biological Psychiatry Global Open Science
Transcutaneous auricular vagus nerve stimulation improves social deficits through the inhibition of IL-17a signaling in a mouse model of autism
Wenjing Zhang, Zhiwei Mou, Qi Zhong, Xiaocao Liu, Yan Lan, Lei Gou, Zhuoming Chen, Kwok‐Fai So, Li Zhang · 2024 · Frontiers in Psychiatry
Maternal immune activation alters temporal Precision of spike generation of CA1 pyramidal neurons by Unbalancing GABAergic inhibition in the Offspring
Ernesto Griego, Camila Cerna, Isabel Sollozo-Dupont, Marco Fuenzalida, Emilio J. Galván · 2024 · Brain Behavior and Immunity
Neonatal infection with Bordetella pertussis promotes autism-like phenotypes in mice
Eoin O′Neill, Lucy M. Curham, Caitlín Ní Chasaide, Síofra O’Brien, Gavin McManus, Barry Moran, Keith Rubin, Steven Glazer, Marina A. Lynch, Kingston H. G. Mills · 2024 · iScience
Prenatal infection predisposes offspring to enhanced susceptibility to imiquimod-mediated psoriasiform dermatitis in mice
Sebastian Yu, Chia-Wen Lee, Yuan Li, Tsung-Hsi Chen, Hsin‐Su Yu · 2022 · Dermatologica Sinica
Influences of the Immune System and Microbiome on the Etiology of ASD and GI Symptomology of Autistic Individuals
Amanda J. H. Kim, Corina R. Zisman, Calliope Holingue · 2022 · Current topics in behavioral neurosciences
A new age for (mucosal) NeuroImmunology
Gérard Eberl · 2022 · Mucosal Immunology
Intrauterine Inflammation Leads to Select Sex- and Age-Specific Behavior and Molecular Differences in Mice
Ana G. Cristancho, Natalia M. Tulina, Amy G. Brown, Lauren Anton, Guillermo Barila, Michal A. Elovitz · 2022 · International Journal of Molecular Sciences
Interplay Between the Immune and Nervous Cognitive Systems in Homeostasis and in Malaria
Luciana Pereira de Sousa, Pamela Rosa-Gonçalves, Flávia Lima Ribeiro-Gomes, Cláudio Tadeu Daniel‐Ribeiro · 2023 · International Journal of Biological Sciences
Aflatoxin B1 Exposure Aggravates Neurobehavioral Deficits and Immune Dysfunctions of Th1, Th9, Th17, Th22, and T Regulatory Cell-Related Transcription Factor Signaling in the BTBR T+Itpr3tf/J Mouse Model of Autism
Mohammad Y. Alwetaid, Taghreed N. Almanaa, Saleh A. Bakheet, Mushtaq Ahmad Ansari, Ahmed Nadeem, Sabry Mohamed Attia, Marwa H. Hussein, Sheikh F. Ahmad · 2023 · Brain Sciences
Brain methylome remodeling selectively regulates neuronal activity genes linking to emotional behaviors in mice exposed to maternal immune activation
Li Ma, Feng Wang, Yangping Li, Jing Wang, Qing Chang, Yuanning Du, Jotham Sadan, Zhen Zhao, Guoping Fan, Bing Yao et al. · 2023 · Nature Communications
Blood borne: Bacterial components in mother’s blood influence fetal development
Allister J. Loughran, ELAINE I. TUOMANEN · 2016 · Inflammation and Cell Signaling
Elucidation of molecular pathogenesis and drug development for psychiatric disorders from rare disease-susceptibility variants
Hiroki Kimura, Daisuke Mori, Branko Aleksić, Norio Ozaki · 2020 · Neuroscience Research
Autophagy in Neurodevelopmental Disorders
Meihong Lv, Quanhong Ma · 2020 · Advances in experimental medicine and biology
Immuno-psychiatrie et pandémie de SARS-CoV-2 : liens et possibles conséquences
J. Daaboul, Ryad Tamouza, Marion Leboyer · 2020 · L Encéphale
Tightening the Case for Gut Microbiota in Autism-Spectrum Disorder
Jonathan Braun · 2017 · Cellular and Molecular Gastroenterology and Hepatology