Huh, Jun R.

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

Clark, I. E., Dodson, M. W., Jiang, C., Cao, J. H., Huh, J. R., Seol, J. H., Yoo, S. J., Hay, B. A., & Guo, M. (2006) · Nature

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 1,788

Bile acid metabolites control TH17 and Treg cell differentiation

Hang, S., Paik, D., Yao, L., Kim, E., Trinath, J., Lu, J., Ha, S., Nelson, B. N., Kelly, S. P., Wu, L., et al. (2019) · Nature

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 1,457

The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring

Choi, G. B., Yim, Y. S., Wong, H., Kim, S., Kim, H., Kim, S. V., Hoeffer, C. A., Littman, D. R., & Huh, J. R. (2016) · Science

Autism Spectrum Disorder ResearchTryptophan and brain disorders

Cited by 1,214

Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring

Kim, S., Kim, H., Yim, Y. S., Ha, S., Atarashi, K., Tan, T. G., Longman, R. S., Honda, K., Littman, D. R., Choi, G. B., et al. (2017) · Nature

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 678

Human gut bacteria produce ΤΗ17-modulating bile acid metabolites

Paik, D., Yao, L., Zhang, Y., Bae, S., D’Agostino, G. D., Zhang, M., Kim, E., Franzosa, E. A., Avila-Pacheco, J., Bisanz, J. E., et al. (2022) · Nature

Gut microbiota and healthInflammatory Bowel Disease

Cited by 594

Population snapshots predict early haematopoietic and erythroid hierarchies

Tusi, B. K., Wolock, S. L., Weinreb, C., Hwang, Y., Hidalgo, D., Zilionis, R., Waisman, A., Huh, J. R., Klein, A. M., & Socolovsky, M. (2018) · Nature

Hematopoietic Stem Cell TransplantationSingle-cell and spatial transcriptomics

Cited by 384

Microbiota and the gut-brain-axis: Implications for new therapeutic design in the CNS

Liu, L., Huh, J. R., & Shah, K. (2022) · eBioMedicine

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 344

A bacterial bile acid metabolite modulates Treg activity through the nuclear hormone receptor NR4A1

Li, W., Hang, S., Fang, Y., Bae, S., Zhang, Y., Zhang, M., Wang, G., McCurry, M. D., Bae, M., Paik, D., et al. (2021) · Cell Host & Microbe

Gut microbiota and healthT-cell and B-cell Immunology

Cited by 306

Reversing behavioural abnormalities in mice exposed to maternal inflammation

Shin Yim, Y., Park, A., Berrios, J., Lafourcade, M., Pascual, L. M., Soares, N., Yeon Kim, J., Kim, S., Kim, H., Waisman, A., et al. (2017) · Nature

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 303

IL-17a promotes sociability in mouse models of neurodevelopmental disorders

Reed, M. D., Yim, Y. S., Wimmer, R. D., Kim, H., Ryu, C., Welch, G. M., Andina, M., King, H. O., Waisman, A., Halassa, M. M., et al. (2020) · Nature

Autism Spectrum Disorder ResearchTryptophan and brain disorders

Cited by 274

Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma

Guerra, E. S., Lee, C. K., Specht, C. A., Yadav, B., Huang, H., Akalin, A., Huh, J. R., Mueller, C., & Levitz, S. M. (2017) · PLOS Pathogens

Asthma and respiratory diseasesIL-33, ST2, and ILC Pathways

Cited by 88