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The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

De novo assembly of the Aedes aegypti genome using Hi-C yields chromosome-length scaffolds

Open access
Dudchenko, Olga, Batra, Sanjit S., Omer, Arina D., Nyquist, Sarah K., Hoeger, Marie, Durand, Neva C., Shamim, Muhammad S., Machol, Ido, Lander, Eric S., Aiden, Aviva Presser, Aiden, Erez Lieberman·2017·Science

Abstract

Hi-C for mosquito genomes: Most genomes sequenced today are determined through the generation of short sequenced bits of DNA that are computationally pieced together like a jigsaw puzzle. This has resulted in the need for funds and additional data to fill in gaps in order to fully assemble the many chromosomes that make up a eukaryotic genome. Dudchenko et al. used the Hi-C method, which measures the distance between contact points within and between chromosomes for scaffold validation, together with correction and ordering to more completely determine the arrangement of short sequencing reads for genome mapping. They validated their approach through the de novo generation of a complete human genome. A comparative analysis of mosquito genomes was made possible by improving the Culex quinquefasciatus genome assembly and generating the genome of Aedes aegypti , the vector of Zika virus. Science , this issue p. 92

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Metadata

Authors
Dudchenko, O., Batra, S. S., Omer, A. D., Nyquist, S. K., Hoeger, M., Durand, N. C., Shamim, M. S., Machol, I., Lander, E. S., Aiden, A. P., & Aiden, E. L.
Venue
Science
Published
2017-04-07
Volume
356
Issue
6333
Pages
92-95
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2396077153
Cited by
2,784
References
4
FWCI
32.13
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: De novo assembly of the Aedes aegypti genome using Hi-C yields chromosome-length scaffolds. https://app.cochat.ai/papers/10.1126/science.aal3327
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Dudchenko, O., Batra, S. S., Omer, A. D., Nyquist, S. K., Hoeger, M., Durand, N. C., Shamim, M. S., Machol, I., Lander, E. S., Aiden, A. P., & Aiden, E. L. (2017). De novo assembly of the Aedes aegypti genome using Hi-C yields chromosome-length scaffolds. Science. https://doi.org/10.1126/science.aal3327

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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