Cited by 188Neural dynamics and brain functionVisual perception and processing mechanismsNeuroscience and Neuropharmacology Research

Learning and attention reveal a general relationship between population activity and behavior

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Ni, A. M., Ruff, D. A., Alberts, J. J., Symmonds, J., Cohen, M. R.·2018·Science

Abstract

The neuronal population is the key unit: The responses of pairs of neurons to repeated presentations of the same stimulus are typically correlated, and an identical neuronal population can perform many functions. This suggests that the relevant units of computation are not single neurons but subspaces of the complete population activity. To test this idea, Ni et al. measured the relationship between neuronal population activity and performance in monkeys. They investigated attention, which improves perception of attended stimuli, and perceptual learning, which improves perception of well-practiced stimuli. These two processes operate on different time scales and are usually studied using different perceptual tasks. Manipulation of attention and learning in the same behavioral trials and the same neuronal populations revealed the dimensions of population activity that matter most for behavior. Science , this issue p. 463

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  • Gain regulation has been suggested to allow downstream decoders to be optimized for diverse stimuli by separating those features.

    “Gain regulation has been suggested to enable networks of neurons to produce distributed representations of stimulus features223, and to allow downstream decoders to be optimized for diverse stimuli by separating those features224.”

    From Mechanisms underlying gain modulation in the cortex (2020) · cites this paper as [224]

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  1. [5]Moreno-Bote R, Nat Neurosci 17, 1410– 1417 (2014). 25195105 PMC4486057

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Authors
Ni, A. M., Ruff, D. A., Alberts, J. J., Symmonds, J., & Cohen, M. R.
Affiliations
University of Pittsburgh (US)
Corresponding author
Cohen, M. R.
Venue
Science
Published
2018-01-26
Volume
359
Issue
6374
Pages
463-465
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2785016696
Cited by
188
References
22
Citations by year
2026: 21 · 2025: 12 · 2024: 13 · 2023: 23 · 2022: 21 · 2021: 39 · 2020: 23 · 2019: 22 · 2018: 11 · 2017: 2 · 2016: 1
FWCI
14.03
Type
journal article
Language
en
Open access
Locations
  • Science (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health (4R00EY020844-03, R01 EY022930, Core Grant P30 EY008098s)
  • McKnight Endowment Fund for Neuroscience
  • Alfred P. Sloan Foundation
  • Simons Foundation
  • Esther A. and Joseph Klingenstein Fund
  • Whitehall Foundation
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords
correlated variability, population activity, perceptual learning, attention, behavioral performance, decision-making, trial-to-trial variability, perceptual performance
MeSH terms
Animals, Haplorhini, Attention, Behavior, Evoked Potentials, Learning, Male, Neurons, Perception

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