The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Digitization of multistep organic synthesis in reactionware for on-demand pharmaceuticals
Open accessAbstract
A plastic plan for organic synthesis: The infrastructure for chemical synthesis typically lies at either end of a spectrum: small-scale studies in ad hoc assemblies of glassware or large-scale production in capital-intensive custom reactors. Kitson et al. report a hybrid protocol that customizes a blueprint for synthesis of a target compound in a series of interconnected plastic modules, which can be assembled en masse by 3D printing (see the Perspective by Hornung). The approach, demonstrated for the commercial muscle relaxant baclofen, establishes a systematic workflow that is potentially amenable to automation: All that is necessary for synthesis and purification is the introduction of stock solutions and variation of temperature or pressure. Science , this issue p. 314 ; see also p. 273
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Evaluation of 3D Printing and Its Potential Impact on Biotechnology and the Chemical Sciences
Gross, B. C., Erkal, J. L., Lockwood, S. Y., Chen, C., & Spence, D. M. (2014) · Analytical Chemistry · doi:10.1021/ac403397r · Cited by 1,746
Recent Advances in Analytical Chemistry by 3D Printing
Gross, B., Lockwood, S. Y., & Spence, D. M. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.6b04344 · Cited by 359
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Metadata
- Authors
- Kitson, P. J., Marie, G., Francoia, J.-P., Zalesskiy, S. S., Sigerson, R. C., Mathieson, J. S., & Cronin, L.
- Venue
- Science
- Published
- 2018-01-19
- Volume
- 359
- Issue
- 6373
- Pages
- 314-319
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2782616083
- Cited by
- 204
- References
- 2
- FWCI
- 11.70
- Type
- journal article
- Language
- en
- Open access
- green
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- Kitson, P. J., Marie, G., Francoia, J.-P., Zalesskiy, S. S., Sigerson, R. C., Mathieson, J. S., & Cronin, L. (2018). Digitization of multistep organic synthesis in reactionware for on-demand pharmaceuticals. Science. https://doi.org/10.1126/science.aao3466
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