The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Systematic discovery of antiphage defense systems in the microbial pangenome
Open accessAbstract
Maps of defense arsenals in microbial genomes: To survive the attack of foreign invaders such as viruses and plasmids, bacteria and archaea fight back with immune systems that are usually clustered in “defense islands” in their genomes. Doron et al. took advantage of this property to map microbial defense systems systematically (see the Perspective by Kim). Candidate immune systems were then experimentally validated for their activities. Like well-known defense arsenals such as restriction-modification and CRISPR systems, these additional immune systems now require mechanistic investigation and could potentially be engineered into useful molecular tools in the future. Science , this issue p. eaar4120 ; see also p. 993
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Cited by
Federici, S., Kredo-Russo, S., Valdés-Mas, R., Kviatcovsky, D., Weinstock, E., Matiuhin, Y., Silberberg, Y., Atarashi, K., Furuichi, M., Oka, A., et al. (2022) · Cell · doi:10.1016/j.cell.2022.07.003 · Cited by 542
Self-citationAn expanded arsenal of immune systems that protect bacteria from phages
Millman, A., Melamed, S., Leavitt, A., Doron, S., Bernheim, A., Hör, J., Garb, J., Bechon, N., Brandis, A., Lopatina, A., et al. (2022) · Cell Host & Microbe · doi:10.1016/j.chom.2022.09.017 · Cited by 428
Self-citationThe Ecology and Evolution of Pangenomes
Brockhurst, M. A., Harrison, E., Hall, J. P. J., Richards, T., McNally, A., & MacLean, C. (2019) · Current Biology · doi:10.1016/j.cub.2019.08.012 · Cited by 385
Large-Scale Analyses of Human Microbiomes Reveal Thousands of Small, Novel Genes
Sberro, H., Fremin, B. J., Zlitni, S., Edfors, F., Greenfield, N., Snyder, M. P., Pavlopoulos, G. A., Kyrpides, N. C., & Bhatt, A. S. (2019) · Cell · doi:10.1016/j.cell.2019.07.016 · Cited by 237
Discovery of phage determinants that confer sensitivity to bacterial immune systems
Stokar-Avihail, A., Fedorenko, T., Hör, J., Garb, J., Leavitt, A., Millman, A., Shulman, G., Wojtania, N., Melamed, S., Amitai, G., et al. (2023) · Cell · doi:10.1016/j.cell.2023.02.029 · Cited by 176
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Metadata
- Authors
- Doron, S., Melamed, S., Ofir, G., Leavitt, A., Lopatina, A., Keren, M., Amitai, G., & Sorek, R.
- Venue
- Science
- Published
- 2018-03-02
- Volume
- 359
- Issue
- 6379
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2784532673
- Cited by
- 1,250
- References
- 5
- FWCI
- 63.19
- Type
- journal article
- Language
- en
- Open access
- green
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