The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.
Light-driven fine chemical production in yeast biohybrids
Open accessAbstract
Light-powered cell factories: Bacteria and fungi are used industrially to produce commodity fine chemicals at vast scale. Sugars are an economical feedstock, but many of the desired products require enzymatic reduction, meaning that some of the sugar must be diverted to regenerate the cellular reductant NADPH (reduced form of nicotinamide adenine dinucleotide phosphate). Guo et al. show that electrons from light-sensitive nanoparticles can drive reduction of cellular NADPH in yeast, which can then be used for reductive biosynthetic reactions. This system can reduce diversion of carbon to NADPH regeneration and should be compatible with many existing engineered strains of yeast. Science , this issue p. 813
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Comparing Photosynthetic and Photovoltaic Efficiencies and Recognizing the Potential for Improvement
Blankenship, R. E., Tiede, D. M., Barber, J., Brudvig, G. W., Fleming, G., Ghirardi, M., Gunner, M. R., Junge, W., Kramer, D. M., Melis, A., et al. (2011) · Science · doi:10.1126/science.1200165 · Cited by 1,638
Self-citationEngineering Cellular Metabolism
Nielsen, J., & Keasling, J. D. (2016) · Cell · doi:10.1016/j.cell.2016.02.004 · Cited by 1,378
Self-photosensitization of nonphotosynthetic bacteria for solar-to-chemical production
Sakimoto, K. K., Wong, A. B., & Yang, P. (2016) · Science · doi:10.1126/science.aad3317 · Cited by 1,162
Self-citationPlant nanobionics approach to augment photosynthesis and biochemical sensing
Giraldo, J. P., Landry, M. P., Faltermeier, S. M., McNicholas, T. P., Iverson, N. M., Boghossian, A. A., Reuel, N. F., Hilmer, A. J., Sen, F., Brew, J. A., et al. (2014) · Nature Materials · doi:10.1038/nmat3890 · Cited by 1,158
Genome-Scale Reconstruction of the Saccharomyces cerevisiae Metabolic Network
Förster, J., Famili, I., Fu, P., Palsson, B. Ø., & Nielsen, J. (2003) · Genome Research · doi:10.1101/gr.234503 · Cited by 1,069
Complete biosynthesis of opioids in yeast
Galanie, S., Thodey, K., Trenchard, I. J., Filsinger Interrante, M., & Smolke, C. D. (2015) · Science · doi:10.1126/science.aac9373 · Cited by 985
Water splitting–biosynthetic system with CO 2 reduction efficiencies exceeding photosynthesis
Liu, C., Colón, B. C., Ziesack, M., Silver, P. A., & Nocera, D. G. (2016) · Science · doi:10.1126/science.aaf5039 · Cited by 971
Self-citationFrom Hydrogenases to Noble Metal–Free Catalytic Nanomaterials for H 2 Production and Uptake
Le Goff, A., Artero, V., Jousselme, B., Tran, P. D., Guillet, N., Métayé, R., Fihri, A., Palacin, S., & Fontecave, M. (2009) · Science · doi:10.1126/science.1179773 · Cited by 955
Light-driven dinitrogen reduction catalyzed by a CdS:nitrogenase MoFe protein biohybrid
Brown, K. A., Harris, D. F., Wilker, M. B., Rasmussen, A., Khadka, N., Hamby, H., Keable, S., Dukovic, G., Peters, J. W., Seefeldt, L. C., et al. (2016) · Science · doi:10.1126/science.aaf2091 · Cited by 868
Manufacturing Molecules Through Metabolic Engineering
Keasling, J. D. (2010) · Science · doi:10.1126/science.1193990 · Cited by 825
Cited by
Third-generation biorefineries as the means to produce fuels and chemicals from CO2
Liu, Z., Wang, K., Chen, Y., Tan, T., & Nielsen, J. (2020) · Nature Catalysis · doi:10.1038/s41929-019-0421-5 · Cited by 469
Artificial Photosynthesis at Efficiencies Greatly Exceeding That of Natural Photosynthesis
Dogutan, D. K., & Nocera, D. G. (2019) · Accounts of Chemical Research · doi:10.1021/acs.accounts.9b00380 · Cited by 398
Self-citationMaterials design by synthetic biology
Tang, T.-C., An, B., Huang, Y., Vasikaran, S., Wang, Y., Jiang, X., Lu, T. K., & Zhong, C. (2020) · Nature Reviews Materials · doi:10.1038/s41578-020-00265-w · Cited by 386
Tardy, B. L., Mattos, B. D., Otoni, C. G., Beaumont, M., Majoinen, J., Kämäräinen, T., & Rojas, O. J. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c01333 · Cited by 267
Metadata
- Authors
- Guo, J., Suástegui, M., Sakimoto, K. K., Moody, V. M., Xiao, G., Nocera, D. G., & Joshi, N. S.
- Venue
- Science
- Published
- 2018-11-16
- Volume
- 362
- Issue
- 6416
- Pages
- 813-816
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2901030934
- Cited by
- 458
- References
- 33
- FWCI
- 10.44
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Light-driven fine chemical production in yeast biohybrids. https://app.cochat.ai/papers/10.1126/science.aat9777
- The paper
- Guo, J., Suástegui, M., Sakimoto, K. K., Moody, V. M., Xiao, G., Nocera, D. G., & Joshi, N. S. (2018). Light-driven fine chemical production in yeast biohybrids. Science. https://doi.org/10.1126/science.aat9777
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
