The DOI matches its Crossref record; 96 of the 96 references it cites were found in a registry or an index.
Antimicrobial peptides: Application informed by evolution
Open accessAbstract
Small-molecule defense: Small-peptide defense molecules are produced by most organisms to fend off invasion by bacteria. The antimicrobial peptides that we know about so far show substantial diversity, synergism, and alternative functions. Lazzaro et al. review our knowledge of the evolution and diversity of antimicrobial peptides, the rapid pharmacodynamics of which make them promising candidates for translational applications to complement efforts to overcome antibiotic resistance. Science , this issue p. eaau5480
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Antimicrobial peptides of multicellular organisms
Zasloff, M. (2002) · Nature · doi:10.1038/415389a · Cited by 8,457
Self-citationAntibiotic resistance-the need for global solutions
Laxminarayan, R., Duse, A., Wattal, C., Zaidi, A. K. M., Wertheim, H. F. L., Sumpradit, N., Vlieghe, E., Hara, G. L., Gould, I. M., Goossens, H., et al. (2013) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(13)70318-9 · Cited by 4,439
Understanding the mechanisms and drivers of antimicrobial resistance
Holmes, A. H., Moore, L. S. P., Sundsfjord, A., Steinbakk, M., Regmi, S., Karkey, A., Guerin, P. J., & Piddock, L. J. V. (2016) · The Lancet · doi:10.1016/s0140-6736(15)00473-0 · Cited by 2,611
APD3: the antimicrobial peptide database as a tool for research and education
Wang, G., Li, X., & Wang, Z. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkv1278 · Cited by 2,388
Selection of Resistant Bacteria at Very Low Antibiotic Concentrations
Gullberg, E., Cao, S., Berg, O. G., Ilbäck, C., Sandegren, L., Hughes, D., & Andersson, D. I. (2011) · PLoS Pathogens · doi:10.1371/journal.ppat.1002158 · Cited by 1,654
The shared antibiotic resistome of soil bacteria and human pathogens
Forsberg, K. J., Reyes, A., Wang, B., Selleck, E. M., Sommer, M. O. A., & Dantas, G. (2012) · Science · doi:10.1126/science.1220761 · Cited by 1,650
The search for synergy: a critical review from a response surface perspective.
Greco, W. R., Bravo, G., & Parsons, J. C. (1995) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06847-4 · Cited by 1,434
Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis
Bevins, C. L., & Salzman, N. H. (2011) · Nature Reviews Microbiology · doi:10.1038/nrmicro2546 · Cited by 1,238
The co-evolution of host cationic antimicrobial peptides and microbial resistance
Peschel, A., & Sahl, H.-G. (2006) · Nature Reviews Microbiology · doi:10.1038/nrmicro1441 · Cited by 1,062
Lemaitre, B., Reichhart, J.-M., & Hoffmann, J. A. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.26.14614 · Cited by 1,034
Cited by
Antimicrobial Peptides: Classification, Design, Application and Research Progress in Multiple Fields
Huan, Y., Kong, Q., Mou, H., & Yi, H. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.582779 · Cited by 1,595
Biomimetic peptide self-assembly for functional materials
Levin, A., Hakala, T. A., Schnaider, L., Bernardes, G. J. L., Gazit, E., & Knowles, T. P. J. (2020) · Nature Reviews Chemistry · doi:10.1038/s41570-020-0215-y · Cited by 853
Antimicrobial peptides for combating drug-resistant bacterial infections
Xuan, J., Feng, W., Wang, J., Wang, R., Zhang, B., Bo, L., Chen, Z.-S., Yang, H., & Sun, L. (2023) · Drug Resistance Updates · doi:10.1016/j.drup.2023.100954 · Cited by 665
Mechanism of Antimicrobial Peptides: Antimicrobial, Anti-Inflammatory and Antibiofilm Activities
Luo, Y., & Song, Y. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222111401 · Cited by 559
Identification of antimicrobial peptides from the human gut microbiome using deep learning
Ma, Y., Guo, Z., Xia, B., Zhang, Y., Liu, X., Yu, Y., Tang, N., Tong, X., Wang, M., Ye, X., et al. (2022) · Nature Biotechnology · doi:10.1038/s41587-022-01226-0 · Cited by 490
Metadata
- Authors
- Lazzaro, B. P., Zasloff, M., & Rolff, J.
- Venue
- Science
- Published
- 2020-05
- Volume
- 368
- Issue
- 6490
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W3023413280
- Cited by
- 1,069
- References
- 96
- FWCI
- 72.58
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Antimicrobial peptides: Application informed by evolution. https://app.cochat.ai/papers/10.1126/science.aau5480
- The paper
- Lazzaro, B. P., Zasloff, M., & Rolff, J. (2020). Antimicrobial peptides: Application informed by evolution. Science. https://doi.org/10.1126/science.aau5480
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
