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Cited by 665

The DOI matches its Crossref record; 122 of the 122 references it cites were found in a registry or an index.

Antimicrobial peptides for combating drug-resistant bacterial infections

Open access
Xuan, Jiaqi, Feng, Weiguo, Wang, Jiaye, Wang, Ruichen, Zhang, Bowen, Bo, Letao, Chen, Zhe-Sheng, Yang, Hui, Sun, Leming·2023·Drug Resistance Updates

Abstract

The problem of drug resistance due to long-term use of antibiotics has been a concern for years. As this problem grows worse, infections caused by multiple bacteria are expanding rapidly and are extremely detrimental to human health. Antimicrobial peptides (AMPs) are a good alternative to current antimicrobials with potent antimicrobial activity and unique antimicrobial mechanisms, which have advantages over traditional antibiotics in fighting against drug-resistant bacterial infections. Currently, researchers have conducted clinical investigations on AMPs for drug-resistant bacterial infections while integrating new technologies in the development of AMPs, such as changing amino acid structure of AMPs and using different delivery methods for AMPs. This article introduces the basic properties of AMPs, deliberates the mechanism of drug resistance in bacteria and the therapeutic mechanism of AMPs. The current disadvantages and advances of AMPs in combating drug-resistant bacterial infections are also discussed. This article provides important insights into the research and clinical application of new AMPs for drug-resistant bacterial infections.

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Metadata

Authors
Xuan, J., Feng, W., Wang, J., Wang, R., Zhang, B., Bo, L., Chen, Z.-S., Yang, H., & Sun, L.
Venue
Drug Resistance Updates
Publisher
Elsevier BV
Published
2023-05
Volume
68
Pages
100954
ISSN
1368-7646 (ISSN-L)
OpenAlex
W4322754081
Cited by
665
References
122
FWCI
97.14
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Antimicrobial peptides for combating drug-resistant bacterial infections. https://app.cochat.ai/papers/10.1016/j.drup.2023.100954
The paper
Xuan, J., Feng, W., Wang, J., Wang, R., Zhang, B., Bo, L., Chen, Z.-S., Yang, H., & Sun, L. (2023). Antimicrobial peptides for combating drug-resistant bacterial infections. Drug Resistance Updates. https://doi.org/10.1016/j.drup.2023.100954

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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