Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

International Multiple Sclerosis Genetics Consortium, Patsopoulos, Nikolaos A., Baranzini, Sergio E., Santaniello, Adam, Shoostari, Parisa, Cotsapas, Chris, Wong, Garrett, Beecham, Ashley H. +150 more·2019·Science

Cited by (1,491)

Items 301–400 of 1,491

  1. Factors associated with and long-term outcome of benign multiple sclerosis: a nationwide cohort study
    Loes Crielaard, Andrius Kavaliūnas, Ryan Ramanujam, Tomas P Olsson, Jan A. Hillert, Pernilla Stridh, Ingrid Skelton Kockum, Ali Manouchehrinia · 2019 · Journal of Neurology Neurosurgery & Psychiatry
  2. Myeloid cell replacement is neuroprotective in chronic experimental autoimmune encephalomyelitis
    Marius Marc-Daniel Mader, Alan Napole, Danwei Wu, Micaiah Atkins, Alexa Scavetti, Yohei Shibuya, Aulden G. Foltz, Oliver Hahn, Yongjin Yoo, Ron Danziger et al. · 2024 · Nature Neuroscience
  3. Stochastic search and joint fine-mapping increases accuracy and identifies previously unreported associations in immune-mediated diseases
    Jennifer L. Asimit, Daniel B. Rainbow, Mary D Fortune, Nastasiya F. Grinberg, Linda S. Wicker, Chris Wallace · 2019 · Nature Communications
  4. Targeting microglia-oligodendrocyte crosstalk in neurodegenerative and psychiatric disorders.
    R. Rahimian, Kelly Perlman, Candice Canonne, N. Mechawar · 2022 · Drug Discovery Today
  5. Synapse Dysfunctions in Multiple Sclerosis
    Karin Schwarz, Frank Schmitz · 2023 · International Journal of Molecular Sciences
  6. Genome-wide association study identifies risk loci within the major histocompatibility complex region for Hunner-type interstitial cystitis
    Yoshiyuki Akiyama, Kyuto Sonehara, Daichi Maeda, Hiroto Katoh, Tatsuhiko Naito, Kenichi Yamamoto, Koichi Matsuda, Yuji Yamanashi, Yoichi Furukawa, Takayuki Morisaki et al. · 2023 · Cell Reports Medicine
  7. Personalized Use of Disease-Modifying Therapies in Multiple Sclerosis
    Chi‐Yan Lee, Koon‐Ho Chan · 2024 · Pharmaceutics
  8. Dynamic regulatory elements in single-cell multimodal data implicate key immune cell states enriched for autoimmune disease heritability
    Anika Gupta, Kathryn Weinand, Aparna Nathan, Saori Sakaue, Martin Jinye Zhang, Accelerating Medicines Partnership RA/SLE Program and Network, Laura T. Donlin, Kevin Wei, Alkes L. Price, Tiffany Amariuta et al. · 2023 · Nature Genetics
  9. A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans
    Marta Riise Moksnes, Ailin Falkmo Hansen, Brooke N. Wolford, Laurent F. Thomas, Humaira Rasheed, Anica Simić, Laxmi Bhatta, Anne Lise Brantsæter, Ida L. Surakka, Wei Zhou et al. · 2024 · Communications Biology
  10. Exploring the Link Between Genetic Predictors of Cardiovascular Disease and Psoriasis
    Ravi Ramessur, Jake R. Saklatvala, Ashley Budu‐Aggrey, Marek Ostaszewski, Lena Möbus, Dario Greco, ’Matladi N. Ndlovu, Satveer K. Mahil, Jonathan N. Barker, Sara Brown et al. · 2024 · JAMA Cardiology
  11. CLEC16A in astrocytes promotes mitophagy and limits pathology in a multiple sclerosis mouse model
    Atsushi Kadowaki, Michael A. Wheeler, Zhaorong Li, Brian M. Andersen, Hong‐Gyun Lee, Tomer Illouz, Joon-Hyuk Lee, Alain Ndayisaba, Stéphanie Zandee, Himanish Basu et al. · 2025 · Nature Neuroscience
  12. SLAMF7 modulates B cells and adaptive immunity to regulate susceptibility to CNS autoimmunity
    Patrick M. O’Connell, Maja K. Blake, Sarah Godbehere, Andrea Amalfitano, Yasser Ali Aldhamen · 2022 · Journal of Neuroinflammation
  13. Impact of disease-modifying therapy on dendritic cells and exploring their immunotherapeutic potential in multiple sclerosis
    Caiyun Liu, Jie Zhu, Yan Mi, Tao Jin · 2022 · Journal of Neuroinflammation
  14. Cerebral organoids in primary progressive multiple sclerosis reveal stem cell and oligodendrocyte differentiation defect
    N. Daviaud, E. Chen, Tara Edwards, S. Sadiq · 2023 · Biology Open
  15. Emerging Perspectives on MRI Application in Multiple Sclerosis: Moving from Pathophysiology to Clinical Practice
    Maria Assunta Rocca, Monica Margoni, Marco Battaglini, Arman Eshaghi, Jeffrey J. Iliff, Elisabetta Pagani, Paolo Preziosa, Loredana Storelli, Toshiaki Taoka, Paola Valsasina et al. · 2023 · Radiology
  16. Trans-eQTL mapping in gene sets identifies network effects of genetic variants
    Lili Wang, Nikita Babushkin, Zhonghua Liu, Xuanyao Liu · 2024 · Cell Genomics
  17. The Effect of Peripheral Immune Cell Counts on the Risk of Multiple Sclerosis: A Mendelian Randomization Study
    Di He, Liyang Liu, Dongchao Shen, Peng Zou, Liying Cui · 2022 · Frontiers in Immunology
  18. Disease-modifying therapies for Parkinson disease: lessons from multiple sclerosis
    Lorraine V. Kalia, Angelica Asis, Nathalie Arbour, Amit Bar‐Or, Riley M. Bove, Daniel G. Di Luca, Edward A. Fon, Susan Helen Fox, Ziv Gan‐Or, Jennifer L. Gommerman et al. · 2024 · Nature Reviews Neurology
  19. Stressful life events are associated with the risk of multiple sclerosis
    Xia Jiang, Tomas P Olsson, Jan A. Hillert · 2020 · European Journal of Neurology
  20. Siblings reduce multiple sclerosis risk by preventing delayed primary Epstein–Barr virus infection
    Klaus Rostgaard, Nete Munk Nielsen, Mads Melbye, Morten Frisch, Henrik Hjalgrim · 2022 · Brain
  21. Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes
    Amand Floriaan Schmidt, Roshni Joshi, María Gordillo‐Marañón, Fotios Drenos, Pimphen Charoen, Claudia Giambartolomei, Joshua C. Bis, Tom R. Gaunt, Alun David Hughes, Debbie A. Lawlor et al. · 2023 · Communications Medicine
  22. Shared genetic loci between Alzheimer's disease and multiple sclerosis: Crossroads between neurodegeneration and immune system
    Vera Fominykh, Alexey A. Shadrin, Piotr Pawel Jaholkowski, Shahram Bahrami, Lavinia Athanasiu, Douglas P. Wightman, Emil Uffelmann, Daniëlle Posthuma, Geir Selbæk, Anders Martin Dale et al. · 2023 · Neurobiology of Disease
  23. The future of diagnosis in clinical neurosciences: Comparing multiple sclerosis and schizophrenia
    Błażej Misiak, Jerzy Samochowiec, Krzysztof Kowalski, Wolfgang Gäebel, Claudio L. Bassetti, Andrew Chan, Philip A. P. M. Gorwood, Sergi Papiol, Geert Dom, Umberto Volpe et al. · 2023 · European Psychiatry
  24. Genetic and gene expression signatures in multiple sclerosis
    Nikolaos A. Patsopoulos, Philip L. De Jager · 2020 · Multiple Sclerosis Journal
  25. Role of fenofibrate in multiple sclerosis
    Ahmad Abdulaziz Abulaban, Hayder Mutter Al-Kuraishy, Ali Ismail Al-Gareeb, Engy Elekhnawy, Asma Alanazi, Athanasios T. Alexiou, Marios Papadakis, Gaber El‐Saber Batiha · 2024 · European journal of medical research
  26. The phenotypic and genetic association between endometriosis and immunological diseases
    Nina Shigesi, Holly Ruth Harris, Hai Fang, Anne Ndungu, Matthew R. Lincoln, Chris J. Cotsapas, Julian Charles Knight, Stacey A. Missmer, Andrew P. Morris, Christian Malte Becker et al. · 2025 · Human Reproduction
  27. Serum Uric Acid Level and Multiple Sclerosis: A Mendelian Randomization Study
    Peng‐Peng Niu, Bo Song, Xue Wang, Yuming Xu · 2020 · Frontiers in Genetics
  28. Immunoregulatory effects and therapeutic potential of vitamin D in multiple sclerosis
    Wei Zhen Yeh, Melissa M. Gresle, Vilija Jokubaitis, Jim M. Stankovich, Anneke van der Walt, Helmut Butzkueven · 2020 · British Journal of Pharmacology
  29. Genomic, proteomic, and systems biology approaches in biomarker discovery for multiple sclerosis
    Carol Chase Huizar, Itay Raphael, Thomas G. Forsthuber · 2020 · Cellular Immunology
  30. Immune Regulation in Time and Space: The Role of Local- and Long-Range Genomic Interactions in Regulating Immune Responses
    Liam P. Devenish, Musa M. Mhlanga, Yutaka Negishi · 2021 · Frontiers in Immunology
  31. Relationship between Multiple Sclerosis-Associated IL2RA Risk Allele Variants and Circulating T Cell Phenotypes in Healthy Genotype-Selected Controls
    Sophie Buhelt, Helle Bach Søndergaard, Annette Bang Oturai, Henrik Ullum, Marina Rode von Essen, Finn Thorup Sellebjerg · 2019 · Cells
  32. Author Correction: Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets
    Jing Hua Zhao, David Stacey, Niclas Eriksson, Erin Macdonald-Dunlop, Åsa K. Hedman, Anette Kalnapenkis, Stefan Enroth, Domenico Cozzetto, Jonathan L. Digby-Bell, Jonathan Marten et al. · 2023 · Nature Immunology
  33. High-Resolution Transcriptomic and Proteomic Profiling of Heterogeneity of Brain-Derived Microglia in Multiple Sclerosis
    Anneke Miedema, Marion H. C. Wijering, Bart J. L. Eggen, Susanne M. Kooistra · 2020 · Frontiers in Molecular Neuroscience
  34. Association of Body Mass Index in Adolescence and Young Adulthood and Long-term Risk of Multiple Sclerosis
    Rune Alexander Høglund, Helmut E. Meyer, Hein Stigum · 2021 · Neurology
  35. Altered Plasma Metabolic Profiles in Chinese Patients With Multiple Sclerosis
    Fan Yang, Shaochang Wu, Zongxin Ling, Chao Shan, Lijuan Zhang, Xiumei Yan, Lin He, Limei Yu, Na Zhao · 2021 · Frontiers in Immunology
  36. Sleep, Pain, and Neurodegeneration: A Mendelian Randomization Study
    Sandeep Grover, Manu Sharma · 2022 · Frontiers in Neurology
  37. Myeloid caspase-8 restricts RIPK3-dependent proinflammatory IL-1β production and CD4 T cell activation in autoimmune demyelination
    Sun-Ja Kim, Hsueh Chung Lu, Andrew J. Steelman, Jianrong Li · 2022 · Proceedings of the National Academy of Sciences
  38. MED13 and Glycolysis Are Conserved Modifiers of α-Synuclein-Associated Neurodegeneration
    Mengda Ren, Ying Yang, Kelsey Hwee Yee Heng, Lu Yi Ng, Claris Yuin-Yi Chong, Yan Ting Ng, Srinivas Gorur-Shandilya, Rachel Min Qi Lee, Kah Leong Lim, Jing Zhang et al. · 2022 · Cell Reports
  39. A genetic variant associated with multiple sclerosis inversely affects the expression of CD58 and microRNA-548ac from the same gene
    Michael Hecker, Nina Boxberger, Nicole Illner, Brit Fitzner, Ina Schröder, Alexander Winkelmann, Aleš Dudešek, Stefanie Meister, Dirk Koczan, Peter Lorenz et al. · 2019 · PLoS Genetics
  40. The Worm-Specific Immune Response in Multiple Sclerosis Patients Receiving Controlled Trichuris suis Ova Immunotherapy
    Ivet A. Yordanova, Friederike Ebner, Axel Ronald Schulz · 2021 · Life
  41. Chickenpox and multiple sclerosis: A Mendelian randomization study
    Gaizhi Zhu, Shan Yu Zhou, Yaqi Xu, Ran Gao, Min Zhang, Qi Zeng, Wenting Su, Renxi Wang · 2022 · Journal of Medical Virology
  42. Microglia regulate myelin clearance and cholesterol metabolism after demyelination via interferon regulatory factor 5
    Alejandro Montilla, Alazne Zabala, Ibai Calvo, Marina Bosch-Juan, Irene Tomé Velasco, Paloma Mata, Mirjam Koster, Amanda Sierra, Susanne M. Kooistra, Federico Nicolás Soria et al. · 2025 · Cellular and Molecular Life Sciences
  43. The global prevalence of familial multiple sclerosis: an updated systematic review and meta-analysis
    Naeim Ehtesham, Maryam Zare Rafie, Meysam Mosallaei · 2021 · BMC Neurology
  44. High-dimensional immune profiling identifies a biomarker to monitor dimethyl fumarate response in multiple sclerosis
    Martin Diebold, Edoardo Galli, Andreas Kopf, Nicholas Sanderson, Ilaria Callegari, Pascal Benkert, Nicolás Gonzalo Núñez, Florian Ingelfinger, Stefan Herms, Sven Cichon et al. · 2022 · Proceedings of the National Academy of Sciences
  45. Physical activity and risk of multiple sclerosis: A Mendelian randomization study
    Chunyu Li, Junyu Lin, Tianmi Yang, Yi Xiao, Qirui Jiang, Huifang Shang · 2022 · Frontiers in Immunology
  46. Investigation of the causal relationship between ALS and autoimmune disorders: a Mendelian randomization study
    Paria Alipour, Konstantin A. Senkevich, Jay P. Ross, Dan Spiegelman, Despoina Manousaki, Patrick A. Dion, Guy Armand Rouleau · 2022 · BMC Medicine
  47. The circular RNA landscape in multiple sclerosis: Disease-specific associated variants and exon methylation shape circular RNA expression profile
    Giulia Cardamone, Elvezia Maria Paraboschi, Giulia Soldà, Giuseppe Liberatore, Valeria Rimoldi, Javier Cibella, Federica Airi, Veronica Tisato, Claudia Cantoni, Francesca Gallia et al. · 2022 · Multiple Sclerosis and Related Disorders
  48. Whole-blood methylation signatures are associated with and accurately classify multiple sclerosis disease severity
    Maria Pia Campagna, Alexandre Xavier, Rod A. Lea, Jim M. Stankovich, Vicki E. Maltby, Helmut Butzkueven, Jeannette Lechner‐Scott, Rodney John Scott, Vilija Jokubaitis · 2022 · Clinical Epigenetics
  49. The Role of Microorganisms in the Etiopathogenesis of Demyelinating Diseases
    Jessica Frau, Giancarlo Coghe, Lorena Lorefice, Giuseppe Fenu, Eleonora E. Cocco · 2023 · Life
  50. The RNA helicase DDX39B activates FOXP3 RNA splicing to control T regulatory cell fate
    Minato Hirano, Gaddiel Galarza-Muñoz, Geraldine Schott, Liuyang Wang, Chloe K. Nagasawa, Alejandro L. Antonia, Vaibhav Jain, Xiaoying Yu, Steven G. Widen, Farren B. S. Briggs et al. · 2023 · eLife
  51. A systematic review of Mendelian randomization studies on multiple sclerosis
    Teresa Fazia, Giulia Nicole Baldrighi, Andrea Nova, Luisa Bernardinelli · 2023 · European Journal of Neuroscience
  52. Assessing the lack of diversity in genetics research across neurodegenerative diseases: A systematic review of the GWAS Catalog and literature
    Caroline Jonson, Kristin S. Levine, Julie Lake, Linnea Hertslet, Lietsel Jones, Dhairya Patel, Jeff Kim, Sara Bandrés‐Ciga, Nancy L. Terry, Ignacio Fernandez Mata et al. · 2024 · Alzheimer s & Dementia
  53. Deconstruction of HLA-DRB1*04:01:01 and HLA-DRB1*15:01:01 class II haplotypes using next-generation sequencing in European-Americans with multiple sclerosis
    Lisa E. Creary, Kalyan C. Mallempati, Sridevi Gangavarapu, Stacy J. Caillier, Jorge R. Oksenberg, Marcelo Fernández-Viña · 2018 · Multiple Sclerosis Journal
  54. Do Cerebral Small Vessel Disease and Multiple Sclerosis Share Common Mechanisms of White Matter Injury?
    Robin B. Brown, Matthew Traylor, Stephen Burgess, Stephen J. Sawcer, Hugh Stephen Markus · 2019 · Stroke
  55. Next-Generation Neuroimmunology: New Technologies to Understand Central Nervous System Autoimmunity
    Gerd Meyer zu Hörste, Catharina C. Groß, Luisa Klotz, Nicholas Schwab, Heinz Wiendl · 2020 · Trends in Immunology
  56. Twin study identifies early immunological and metabolic dysregulation of CD8 + T cells in multiple sclerosis
    Vladyslav Kavaka, Luisa Mutschler, Clara de la Rosa del Val, Klara Eglseer, Ana M. Gómez Martínez, Andrea Flierl‐Hecht, Birgit Betina Ertl-Wagner, Daniel Keeser, Matin Mortazavi, Klaus Seelos et al. · 2024 · Science Immunology
  57. Mendelian randomization identifies proteins involved in neurodegenerative diseases
    Lazaros Belbasis, Sam Morris, Cornelia M. van Duijn, Derrick Bennett, Robin G. Walters · 2025 · Brain
  58. Smoking and multiple sclerosis risk: a Mendelian randomization study
    Marijne Vandebergh, An Goris · 2020 · Journal of Neurology
  59. Prognostic value of natural killer cell/T cell ratios for disease activity in multiple sclerosis
    Max Mimpen, Anne‐Hilde Muris, Linda Rolf, Oliver H.H. Gerlach, Jens Kühle, Raymond Hupperts, Joost Smolders, Jan G.M.C. Damoiseaux · 2020 · European Journal of Neurology
  60. Mendelian randomization provides no evidence for a causal role in the bidirectional relationship between depression and multiple sclerosis
    Adil Harroud, Ruth Ann Marrie, Kathryn C. Fitzgerald, Amber R. Salter, Yi Lu, Mitulkumar Patel, Kaarina Kowalec · 2021 · Multiple Sclerosis Journal
  61. DRB1–environment interactions in multiple sclerosis etiology: results from two Swedish case–control studies
    Anna Karin Hedström, Jan A. Hillert, Nicole Brenner, Julia Butt, Tim Waterboer, Pernilla Stridh, Ingrid Skelton Kockum, Tomas P Olsson, Lars S. Alfredsson · 2021 · Journal of Neurology Neurosurgery & Psychiatry
  62. Factors affecting the risk of relapsing-onset and progressive-onset multiple sclerosis
    Anna Karin Hedström, Jan A. Hillert, Tomas P Olsson, Lars S. Alfredsson · 2021 · Journal of Neurology Neurosurgery & Psychiatry
  63. What telomeres teach us about MS
    Annalise E. Miner, Jennifer Graves · 2021 · Multiple Sclerosis and Related Disorders
  64. Neonatal neuronal WWOX gene therapy rescues Wwox null phenotypes
    Srinivasarao Repudi, I. M. Kustanovich, Sara Abu‐Swai, Shani Stern, Rami I. Aqeilan · 2021 · EMBO Molecular Medicine
  65. A Systematic Review of Tissue and Single Cell Transcriptome/Proteome Studies of the Brain in Multiple Sclerosis
    Maria L. Elkjaer, Richard Röttger, Jan Baumbach, Zsolt Illés · 2022 · Frontiers in Immunology
  66. Epstein-Barr virus, interleukin-10 and multiple sclerosis: A ménage à trois
    Günther Schönrich, Mohammed O. Abdelaziz, Martin J. Raftery · 2022 · Frontiers in Immunology
  67. Activation of TRPV1 receptor facilitates myelin repair following demyelination via the regulation of microglial function
    Jingxian Sun, Keying Zhu, Yumeng Wang, Dan-jie Wang, Mi-zhen Zhang, Heela Sarlus, Irene Benito‐Cuesta, Xiao-qiang Zhao, Zaofeng Zou, Qing-yang Zhong et al. · 2022 · Acta Pharmacologica Sinica
  68. The rs4759314 SNP within Hotair lncRNA is associated with risk of multiple sclerosis
    Mohammad Naser Taheri, Rezvan Noroozi, Saba Sadeghpour, Mir Davood Omrani, Soudeh Ghafouri‐Fard · 2020 · Multiple Sclerosis and Related Disorders
  69. The shared genetic risk architecture of neurological and psychiatric disorders: a genome-wide analysis
    Olav Bjerkehagen Smeland, Gleda Kutrolli, Shahram Bahrami, Vera Fominykh, Nadine Parker, Guy Hindley, Linn Nilsen Rødevand, Piotr Pawel Jaholkowski, Markos Tesfaye, Pravesh Parekh et al. · 2023 · medRxiv
  70. Emergence of the brain-border immune niches and their contribution to the development of neurodegenerative diseases
    Li Yang Tan, Grace Cunliffe, Michael Patrick Hogan, Xin Yi Yeo, Chansik Oh, Bohwan Jin, Junmo Kang, Junho Park, Min‐Soo Kwon, MinYoung Kim et al. · 2024 · Frontiers in Immunology
  71. Exploring the role of sex hormones and gender diversity in multiple sclerosis
    Cassie Nesbitt, Anneke van der Walt, Helmut Butzkueven, Ada S. Cheung, Vilija Jokubaitis · 2024 · Nature Reviews Neurology
  72. EBNA-1 titer gradient in families with multiple sclerosis indicates a genetic contribution
    Julia Y. Mescheriakova, Gijsbert P. van Nierop, Annemiek A. van der Eijk, Karim L. Kreft, Rogier Q. Hintzen · 2020 · Neurology Neuroimmunology & Neuroinflammation
  73. Involvement of Genetic Factors in Multiple Sclerosis
    Laura Ferrè, Massimo Filippi, Federica Esposito · 2020 · Frontiers in Cellular Neuroscience
  74. Gender and the Sex Hormone Estradiol Affect Multiple Sclerosis Risk Gene Expression in Epstein-Barr Virus-Infected B Cells
    Jeremy Thomas Keane, Ali Afrasiabi, Stephen D. Schibeci, Nicole Fewings, Grant Peter Parnell, Sanjay Swaminathan, David Richmond Booth · 2021 · Frontiers in Immunology
  75. Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome
    Tina Roostaei, Hans‐Ulrich Klein, Yiyi Ma, Daniel Felsky, Pia Kivisäkk, Sarah M. Connor, Alexandra Kroshilina, Christina J. Yung, Belinda J. Kaskow, Xiaorong Shao et al. · 2021 · Nature Communications
  76. Adverse Drug Reactions with Drugs Used in Multiple Sclerosis: An Analysis from the Italian Pharmacovigilance Database
    María Antonietta Barbieri, Emanuela Elisa Sorbara, Alessandro Battaglia · 2022 · Frontiers in Pharmacology
  77. B-Cell-Directed Therapies: A New Era in Multiple Sclerosis Treatment
    Panagiotis Kanatas, Ioannis Stouras, Leonidas Stefanis, Panos Stathopoulos · 2022 · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
  78. Dissection of multiple sclerosis genetics identifies B and CD4+ T cells as driver cell subsets
    Michael H. Guo, Prashanth Sama, Brenna A. LaBarre, Hrishikesh A. Lokhande, John Balibalos, Ci Chu, Xiaomi Du, Pouya Kheradpour, Charles C. Kim, Taylor K. Oniskey et al. · 2022 · Genome biology
  79. Genetic risk variants for multiple sclerosis are linked to differences in alternative pre-mRNA splicing
    Elena Putscher, Michael Hecker, Brit Fitzner, Nina Boxberger, Margit Schwartz, Dirk Koczan, Peter Lorenz, Uwe Klaus Zettl · 2022 · Frontiers in Immunology
  80. The value of Interferon β in multiple sclerosis and novel opportunities for its anti-viral activity: a narrative literature review
    Gianmarco Bellucci, Angela Albanese, Caterina Rizzi, Virginia Rinaldi, Marco Salvetti, Giovanni Ristori · 2023 · Frontiers in Immunology
  81. Investigating the Causal Effect of Brain Expression of CCL2, NFKB1, MAPK14, TNFRSF1A, CXCL10 Genes on Multiple Sclerosis: A Two-Sample Mendelian Randomization Approach
    Teresa Fazia, Andrea Nova, Davide Gentilini, Ashley Harris Beecham, Marialuisa Piras, Valeria Saddi, Anna Ticca, Pierpaolo Bitti, Jacob L. McCauley, Carlo Berzuini et al. · 2020 · Frontiers in Bioengineering and Biotechnology
  82. Mimicking the brain: Epstein-Barr virus and foreign agents as drivers of neuroimmune attack in multiple sclerosis
    Olivia G. Thomas, Tomas P Olsson · 2023 · Frontiers in Immunology
  83. Emerging small-molecule treatments for multiple sclerosis: focus on B cells
    Aaron M. Gregson, Kaitlyn Koenig Thompson, Stella E. Tsirka, David L. Selwood · 2019 · F1000Research
  84. Little evidence for an effect of smoking on multiple sclerosis risk: A Mendelian Randomization study
    Ruth E. Mitchell, Kirsty Bates, Robyn E. Wootton, Adil Harroud, John Brent Richards, George Davey Smith, Marcus Robert Munafo · 2020 · PLoS Biology
  85. Novel cell-based analysis reveals region-dependent changes in microglial dynamics in grey matter in a cuprizone model of demyelination
    Ilias Roufagalas, Maria Avloniti, Alexandra Fortosi, Evangelia Xingi, Dimitra Thomaidou, Lesley Probert, Vasiliki Kyrargyri · 2021 · Neurobiology of Disease
  86. Genome-wide analysis of schizophrenia and multiple sclerosis identifies shared genomic loci with mixed direction of effects
    Mohammad Mehdi Ahangari, Elif Everest, Tan-Hoang Nguyen, Brian C. Verrelli, Bradley Todd Webb, Silviu‐Alin Bacanu, Eda Tahir Turanlı, Brien P. Riley · 2022 · Brain Behavior and Immunity
  87. MINI-review of Epstein-Barr virus involvement in multiple sclerosis etiology and pathogenesis
    Francesca Aloisi, Anne Haney Cross · 2022 · Journal of Neuroimmunology
  88. A survey of genome-wide association studies, polygenic scores and UK Biobank highlights resources for autoimmune disease genetics
    Rochi Saurabh, C. J. K. Fouodo, Inke Regina König, Hauke S. Busch, Inken Wohlers · 2022 · Frontiers in Immunology
  89. The gut microbiome molecular mimicry piece in the multiple sclerosis puzzle
    Noha Salah Elsayed, Paula Aston, Vishnu R. Bayanagari, Sanjay K. Shukla · 2022 · Frontiers in Immunology
  90. Post-transcriptional checkpoints in autoimmunity
    Rami Bechara, Stéphan Vagner, Xavier Mariette · 2023 · Nature Reviews Rheumatology
  91. Cerebrospinal fluid inflammatory biomarkers for disease progression in Alzheimer’s disease and multiple sclerosis: a systematic review
    Joke Temmerman, Sebastiaan Engelborghs, Maria Bjerke, Miguel D’haeseleer · 2023 · Frontiers in Immunology
  92. Relevance of Multiple Sclerosis Severity Genotype in Predicting Disease Course: A Real‐World Cohort
    Karim L. Kreft, Emeka Uzochukwu, Sam Loveless, Mark Willis, Ray Wynford‐Thomas, Katharine Elizabeth Harding, Peter Holmans, Michael Lawton, Emma Clare Tallantyre, Neil P. Robertson · 2023 · Annals of Neurology
  93. Eomes-dependent mitochondrial regulation promotes survival of pathogenic CD4+ T cells during inflammation
    Emeline Joulia, Michaël F. Michieletto, Arantxa Agesta, Cindy Peillex, Virginie Girault, Anne-Louise Le Dorze, Romain Peroceschi, Florence Bucciarelli, Marion Szelechowski, Adeline Chaubet et al. · 2023 · The Journal of Experimental Medicine
  94. The Impact of Microbiota–Immunity–Hormone Interactions on Autoimmune Diseases and Infection
    Serena Martinelli, Giulia Nannini, Fabio Cianchi, Francesco Coratti, Amedeo Amedei · 2024 · Biomedicines
  95. Transcriptional profiling in microglia across physiological and pathological states identifies a transcriptional module associated with neurodegeneration
    Ayşegül Güvenek, Neelroop Parikshak, Daria Zamolodchikov, Sahar Gelfman, Arden Moscati, Lee Dobbyn, Eli A. Stahl, Alan R. Shuldiner, Giovanni Coppola · 2024 · Communications Biology
  96. Non-parametric combination analysis of multiple data types enables detection of novel regulatory mechanisms in T cells of multiple sclerosis patients
    Sunjay Jude Fernandes, Hiromasa Morikawa, Ewoud Ewing, Sabrina Ruhrmann, Rubin Narayan Joshi, Vincenzo Lagani, Nestoras Karathanasis, Mohsen Khademi, Núria Planell, Angelika Schmidt et al. · 2019 · Scientific Reports
  97. Connecting Immune Cell Infiltration to the Multitasking Microglia Response and TNF Receptor 2 Induction in the Multiple Sclerosis Brain
    Caterina Veroni, Barbara Serafini, Barbara Rosicarelli, Corrado Fagnani, Francesca Aloisi, Cristina Agresti · 2020 · Frontiers in Cellular Neuroscience
  98. A single cell-based atlas of human microglial states reveals associations with neurological disorders and histopathological features of the aging brain
    Marta Olah, Vilas Menon, Naomi Habib, Mariko F. Taga, Christina J. Yung, Maria Cimpean, Anthony Khairalla, Danielle Ashley Dionne, Sarah C. Hopp, Matthew P. Frosch et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  99. MiRNA-based therapeutic potential in multiple sclerosis
    Ana Zabalza, Agustín Pappolla, Manuel Comabella, Xavier Montalbán, Sunny Malhotra · 2024 · Frontiers in Immunology
  100. A higher burden of multiple sclerosis genetic risk confers an earlier onset
    Elina Misicka, Mary Feller Davis, Woori Kim, Steven W. Brugger, Jeremy T. Beales, Stephanie J. Loomis, Paola G. Bronson, Farren B. S. Briggs · 2021 · Multiple Sclerosis Journal