Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

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   Agata Matejuk, Arthur A. Vandenbark, Halina Offner · 2021 · Frontiers in Neurology
2. Pathogenesis of autoimmune demyelination: from multiple sclerosis to neuromyelitis optica spectrum disorders and myelin oligodendrocyte glycoprotein antibody‐associated disease
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3. SeXX Matters in Multiple Sclerosis
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4. Diversity and Function of Glial Cell Types in Multiple Sclerosis
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5. Common Peripheral Immunity Mechanisms in Multiple Sclerosis and Alzheimer's Disease
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   Manon Galoppin, Saniya Kari, Sasha GN Soldati, Arindam Pal, Manon Rival, Britta Engelhardt, Anne Astier, Éric Thouvenot · 2022 · Brain Communications
7. Blood–Brain Barrier Disruption in Neuroimmunological Disease
   Fumitaka Shimizu, Masayuki Nakamori · 2024 · International Journal of Molecular Sciences
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   Jian Wang, Yang Wang, Xiakeerzhati Xiaohalati, Qiangfei Su, Jingwei Liu, Bo Cai, Wen Yang, Zheng Wang, Lin Wang · 2023 · Advanced Science
9. Dissecting the human leptomeninges at single-cell resolution
   Kearns, Nicola A., Iatrou, Artemis, Flood, Daniel J., De Tissera, Sashini, Mullaney, Zachary M., Xu, Jishu, Gaiteri, Chris, Bennett, David A., Wang, Yanling · 2023 · Nature Communications
10. Exome sequencing in multiple sclerosis families identifies 12 candidate genes and nominates biological pathways for the genesis of disease
    Carles Vilariño‐Güell, Alexander A. Zimprich, Filippo Martinelli Boneschi, Bruno Herculano, Zhe Wang, Fuencisla Matesanz, Elena Urcelay, Koen Vandenbroeck, Laura Leyva, Denis Gris et al. · 2019 · PLoS Genetics
11. DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning
    Janine Arloth, Gökçen Eraslan, Till F. M. Andlauer, Jade Martins, Stella Iurato, Brigitte Kühnel, Mélanie Waldenberger, Josef Frank, Ralf Gold, Bernhard Hemmer et al. · 2020 · PLoS Computational Biology
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    Wittekindt, Mariela, Kaddatz, Hannes, Joost, Sarah, Staffeld, Anna, Bitar, Yamen, Kipp, Markus, Frintrop, Linda · 2022 · Cells
13. The impact of cell type and context-dependent regulatory variants on human immune traits
    Zepeng Mu, Wei Wei, Benjamin Jung Fair, Jinlin Miao, Ping Zhu, Yang Li · 2021 · Genome biology
14. The Nasal–Brain Drug Delivery Route: Mechanisms and Applications to Central Nervous System Diseases
    Yi Qiu, Shiyuan Huang, Li Peng, Li Yang, Guosong Zhang, Tao Liu, Fang Yan, Xi Peng · 2025 · MedComm
15. Pre-clinical and Clinical Implications of “Inside-Out” vs. “Outside-In” Paradigms in Multiple Sclerosis Etiopathogenesis
    Haley E. Titus, Yanan Chen, Joseph R. Podojil, Andrew P. Robinson, Roumen D. Balabanov, Brian Popko, Stephen D. Miller · 2020 · Frontiers in Cellular Neuroscience
16. Genomic Effects of the Vitamin D Receptor: Potentially the Link between Vitamin D, Immune Cells, and Multiple Sclerosis
    Ming Shian Lu, Bruce V. Taylor, Heinrich Körner · 2018 · Frontiers in Immunology
17. The CD8 T Cell-Epstein-Barr Virus-B Cell Trialogue: A Central Issue in Multiple Sclerosis Pathogenesis
    Caterina Veroni, Francesca Aloisi · 2021 · Frontiers in Immunology
18. Prioritization of autoimmune disease-associated genetic variants that perturb regulatory element activity in T cells
    Kousuke Mouri, Michael H. Guo, Carl G. de Boer, Michelle M. Lissner, Ingrid A. Harten, Gregory A. Newby, Hannah A. DeBerg, Winona F. Platt, Matteo Gentili, David R. Liu et al. · 2022 · Nature Genetics
19. Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progression
    Ewoud Ewing, Lara Kular, Sunjay Jude Fernandes, Nestoras Karathanasis, Vincenzo Lagani, Sabrina Ruhrmann, Ioannis Tsamardinos, Jesper N. Tegner, Fredrik Piehl, David Gómez-Cabrero et al. · 2019 · EBioMedicine
20. Origins and immunopathogenesis of autoimmune central nervous system disorders
    Sudarshini Ramanathan, Fabienne Brilot, Sarosh R. Irani, Russell Clive Dale · 2023 · Nature Reviews Neurology
21. Neuroimmune contributions to Alzheimer’s disease: a focus on human data
    Haage, Verena, De Jager, Philip L. · 2022 · Molecular Psychiatry
22. Microglia Regulate Blood–Brain Barrier Integrity via MiR‐126a‐5p/MMP9 Axis during Inflammatory Demyelination
    Zhongwang Yu, Fang Xue, Weili Liu, Rui Xue Sun, Jintao Zhou, Yingyan Pu, Ming Zhao, Dingya Sun, Zhenghua Xiang, Peng Liu et al. · 2022 · Advanced Science
23. Polygenic risk score association with multiple sclerosis susceptibility and phenotype in Europeans
    Hengameh Shams, Xiaorong Shao, Adam Santaniello, Gina Kirkish, Adil Harroud, Qin Ma, Noriko Isobe, Jessa Alexander, Riley M. Bove, Sergio E. Baranzini et al. · 2022 · Brain
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    Carla Lopes, Sandra Mota, Claudia Deus, Henrique Tavares, Margarida Beatriz · 2022 · Cells
25. Neutrophils in Inflammatory Diseases: Unraveling the Impact of Their Derived Molecules and Heterogeneity
    Bushra Riaz, Seonghyang Sohn · 2023 · Cells
26. The latitude gradient for multiple sclerosis prevalence is established in the early lifecourse.
    C. Sabel, J. Pearson, D. Mason, E. Willoughby, D. Abernethy, B. Taylor · 2021 · Brain : a journal of neurology
27. Anti-CD20 Monoclonal Antibodies for Relapsing and Progressive Multiple Sclerosis
    Finn Thorup Sellebjerg, Morten Blinkenberg, Per Soelberg Sørensen · 2020 · CNS Drugs
28. Crossing boundaries: Interplay between the immune system and oligodendrocyte lineage cells
    Leslie A. Kirby, Gonçalo Castelo‐Branco · 2020 · Seminars in Cell and Developmental Biology
29. B Cells in Neuroinflammation: New Perspectives and Mechanistic Insights
    Julie J. Ahn, Mohammad Abu-Rub, Robert H. Miller · 2021 · Cells
30. The CNS mononuclear phagocyte system in health and disease
    Sarah Mundt, Melanie Greter, Burkhard Becher · 2022 · Neuron
31. DNA Methylation As an Epigenetic Mechanism in the Development of Multiple Sclerosis
    Киселев Иван Сергеевич, О. Г. Кулакова, Аleksey N. Boyko, Olga O. Favorova · 2021 · Acta Naturae
32. Brain macrophages acquire distinct transcriptomes in multiple sclerosis lesions and normal appearing white matter
    Miedema, Anneke, Gerrits, Emma, Brouwer, Nieske, Jiang, Qiong, Kracht, Laura, Meijer, Michel, Nutma, Erik, Peferoen-Baert, Regina, Pijnacker, Anna T. E., Wesseling, Evelyn M. et al. · 2022 · Acta Neuropathologica Communications
33. A genome-wide association study of outcome from traumatic brain injury
    Mart Kals, Kevin Kunzmann, Livia Parodi, Farid Radmanesh, Lindsay Wilson, Saef Izzy, Christopher D. Anderson, Ava M. Puccio, David O. Okonkwo, Nancy R. Temkin et al. · 2022 · EBioMedicine
34. Genetic-Driven Druggable Target Identification and Validation
    Matteo Floris, Stefania Olla, David Schlessinger, Francesco Cucca · 2018 · Trends in Genetics
35. CXCR3+ T cells in multiple sclerosis correlate with reduced diversity of the gut microbiome
    Siobhán Ní Choileáin, Markus Kleinewietfeld, Khadir Raddassi, David A. Hafler, William E. Ruff, Erin E. Longbrake · 2019 · Journal of Translational Autoimmunity
36. The nature of genetic and environmental susceptibility to multiple sclerosis
    Douglas S. Goodin, Pouya Khankhanian, Pierre‐Antoine Gourraud, Nicolas Vince · 2021 · PLoS ONE
37. Natural killer cells in multiple sclerosis: A review
    Max Mimpen, Joost Smolders, Raymond Hupperts, Jan G.M.C. Damoiseaux · 2020 · Immunology Letters
38. Mapping the cellular etiology of schizophrenia and complex brain phenotypes
    Laramie E. Duncan, Tayden Li, Madeleine Salem, Will Li, Leili Mortazavi, Hazal Senturk, Naghmeh Shahverdizadeh, Sam S. Vesuna, Hanyang Shen, Jong H. Yoon et al. · 2025 · Nature Neuroscience
39. Monocytes can efficiently replace all brain macrophages and fetal liver monocytes can generate bona fide SALL1+ microglia
    Jonathan Bastos, Carleigh A. O’Brien, Mónica Vara‐Pérez, Myrthe Mampay, Lynn van Olst, Liam Barry-Carroll, Daliya Kancheva, Sophia Leduc, Ayla Line Lievens, Leen Ali et al. · 2025 · Immunity
40. Childhood obesity and multiple sclerosis: A Mendelian randomization study
    Adil Harroud, Ruth E. Mitchell, Tom G. Richardson, John A. Morris, Vincenzo Forgetta, George Davey Smith, Sergio E. Baranzini, John Brent Richards · 2021 · Multiple Sclerosis Journal
41. Metabolome-based signature of disease pathology in MS
    S.L. Andersen, Farren B. S. Briggs, Janice Winnike, Yanina Natanzon, Sarah Maichle, Kevin J. Knagge, Laura Kristin Newby, Simon G. Gregory · 2019 · Multiple Sclerosis and Related Disorders
42. Gene-Environment Interactions in Multiple Sclerosis
    Benjamin M. Jacobs, Alastair John Noyce, Jonathan Paul Bestwick, Daniel Belete, Gavin Giovannoni, Ruth Dobson · 2021 · Neurology Neuroimmunology & Neuroinflammation
43. Single-cell RNA sequencing of peripheral blood reveals that monocytes with high cathepsin S expression aggravate cerebral ischemia–reperfusion injury
    Lexing Xie, Shuang Zhang, Li Huang, Zhouzhou Peng, Hui Lu, Qian He, Ru Chen, Lin‐Lin Hu, Bingqiao Wang, Baoliang Sun et al. · 2022 · Brain Behavior and Immunity
44. Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity
    Elien Grajchen, Melanie Loix, Paulien Baeten, Beatriz F. Côrte‐Real, Ibrahim Hamad, Sam Vanherle, Mansour Haidar, Jonas Dehairs, Jelle Y. Broos, James Mukasa Ntambi et al. · 2023 · Cellular and Molecular Immunology
45. Paving the way towards an effective treatment for multiple sclerosis: advances in cell therapy
    María José Mansilla, Silvia Presas‐Rodríguez, Aina Teniente‐Serra, Íñigo González-Larreategui, Bibiana Quirant‐Sánchez, Federico Fondelli, Neda Djedović, Dorota Iwaszkiewicz‐Grześ, Kamil Chwojnicki, Djordje M. Miljković et al. · 2021 · Cellular and Molecular Immunology
46. Overview of Genotyping Technologies and Methods
    Ingrid Skelton Kockum, Jesse Huang, Pernilla Stridh · 2023 · Current Protocols
47. Recent advances in understanding multiple sclerosis
    Peter K. Stys, Shigeki Tsutsui · 2019 · F1000Research
48. WWOX Loss of Function in Neurodevelopmental and Neurodegenerative Disorders
    C. Marcelo Aldaz, Tabish Hussain · 2020 · International Journal of Molecular Sciences
49. Risk factors for multiple sclerosis in the context of Epstein-Barr virus infection
    Anna Karin Hedström · 2023 · Frontiers in Immunology
50. Deciphering the tumor immune microenvironment from a multidimensional omics perspective: insight into next-generation CAR-T cell immunotherapy and beyond
    Zhaokai Zhou, Jiahui Wang, Jiaojiao Wang, Shuai Yang, Ruizhi Wang, Ge Zhang, Zhengrui Li, Run Shi, Zhan Wang, Qiong Lu · 2024 · Molecular Cancer
51. Antibody reactivity against EBNA1 and GlialCAM differentiates multiple sclerosis patients from healthy controls
    Neda Sattarnezhad, Ingrid Skelton Kockum, Olivia G. Thomas, Yicong Liu, Peggy Pui-Kay Ho, Alison K. Barrett, Alexandros I. Comanescu, Tilini U. Wijeratne, Paul J. Utz, Lars S. Alfredsson et al. · 2025 · Proceedings of the National Academy of Sciences
52. Multiple sclerosis risk factors contribute to onset heterogeneity
    Farren B. S. Briggs, Justin C. Yu, Mary Feller Davis, Jinghong Jiangyang, Shannon Fu, Erica Parrotta, Douglas David Gunzler, Daniel Ontaneda · 2018 · Multiple Sclerosis and Related Disorders
53. Lactobacillaceae differentially impact butyrate-producing gut microbiota to drive CNS autoimmunity
    Theresa L. Montgomery, Lucinda C. Toppen, Korin M. Eckstrom, Eamonn R. Heney, Josephine J. Kennedy, Matthew Scarborough, Dimitry N. Krementsov · 2024 · Gut Microbes
54. Fatty acids role in multiple sclerosis as “metabokines”
    Haojun Yu, Shuwei Bai, Yong Hao, Yangtai Guan · 2022 · Journal of Neuroinflammation
55. TREM2 ‐dependent microglial function is essential for remyelination and subsequent neuroprotection
    Yuanyuan Wang, Roxanne V. Kyauk, Yun‐An A. Shen, Luke Xie, Mike Reichelt, Han Lin, Zhiyu Jiang, Hai Ngu, Kimberle Shen, Jacob J. Greene et al. · 2023 · Glia
56. How does neurovascular unit dysfunction contribute to multiple sclerosis?
    Jake M. Cashion, Kaylene M. Young, Brad A. Sutherland · 2023 · Neurobiology of Disease
57. Chronic fatigue and depression due to multiple sclerosis: Immune-inflammatory pathways, tryptophan catabolites and the gut-brain axis as possible shared pathways
    Heidi Ormstad, Cecilia Smith Simonsen, Line Broch, Michael H. J. Maes, George Anderson, Elisabeth Gulowsen Celius · 2020 · Multiple Sclerosis and Related Disorders
58. The chromatin landscape of Th17 cells reveals mechanisms of diversification of regulatory and pro-inflammatory states
    Thakore, Pratiksha I., Schnell, Alexandra, Zhao, Maryann, Huang, Linglin, Hou, Yu, Christian, Elena, Zaghouani, Sarah, Wang, Chao, Singh, Vasundhara, Ma, Sai et al. · 2022
59. Targeting RIPK1 kinase for modulating inflammation in human diseases
    Wanjin Li, Junying Yuan · 2023 · Frontiers in Immunology
60. VDR Gene Single Nucleotide Polymorphisms and Autoimmunity: A Narrative Review
    Cristina Agliardi, Franca Rosa Guerini, Elisabetta Bolognesi, Milena Zanzottera, Mario Clerici · 2023 · Biology
61. Shared Genetic Liability and Causal Associations Between Major Depressive Disorder and Cardiovascular Diseases
    Fuquan Zhang, Hongbao Cao, Ancha V. Baranova · 2021 · Frontiers in Cardiovascular Medicine
62. Genome sequencing uncovers phenocopies in primary progressive multiple sclerosis
    Xiaoming Jia, Lohith Madireddy, Stacy J. Caillier, Adam Santaniello, Federica Esposito, Gıancarlo Comı, Olaf Stüve, Yuan Zhou, Bruce V. Taylor, Trevor John Kilpatrick et al. · 2018 · Annals of Neurology
63. X Chromosome Contribution to the Genetic Architecture of Primary Biliary Cholangitis
    Asselta, Rosanna, Paraboschi, Elvezia M., Gerussi, Alessio, Cordell, Heather J., Mells, George F., Sandford, Richard N., Jones, David E., Nakamura, Minoru, Ueno, Kazuko, Hitomi, Yuki et al. · 2021 · Gastroenterology
64. Autophagy in Multiple Sclerosis: Two Sides of the Same Coin
    Chairi Misrielal, Mario Mauthe, Fulvio Reggiori, Bart J. L. Eggen · 2020 · Frontiers in Cellular Neuroscience
65. Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood
    Yi‐Jun Ge, Ya‐Nan Ou, Yue‐Ting Deng, Bang‐Sheng Wu, Yang Liu, Ya-Ru Zhang, Shi-Dong Chen, Yuyuan Huang, Qiang Dong, Lan Tan et al. · 2022 · Biological Psychiatry
66. Multiple sclerosis: role of meningeal lymphoid aggregates in progression independent of relapse activity
    Richard M. Ransohoff · 2023 · Trends in Immunology
67. Evidence from genome wide association studies implicates reduced control of Epstein-Barr virus infection in multiple sclerosis susceptibility
    Ali Afrasiabi, Grant Peter Parnell, Nicole Fewings et al. · 2019 · Genome Medicine
68. Single-nucleus sequencing reveals enriched expression of genetic risk factors in extratelencephalic neurons sensitive to degeneration in ALS
    Francesco Limone, Daniel A. Mordes, Alexander Couto, Brian J. Joseph, Jana M. Mitchell, Martine Therrien, Sulagna Dia Ghosh, Daniel Meyer, Yingying Zhang, Melissa Goldman et al. · 2024 · Nature Aging
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    Marta Sidoryk‐Wȩgrzynowicz, Lidia Strużyńska · 2021 · International Journal of Molecular Sciences
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    Hanane Touil, Kristin Mounts, Philip L. De Jager · 2023 · Frontiers in Immunology
71. CD80 on Human T Cells Is Associated With FoxP3 Expression and Supports Treg Homeostasis
    Blagoje Soskic, Louisa E. Jeffery, Alan Kennedy, David H. Gardner, Tie Zheng Hou, Neil Halliday, Cayman Williams, Daniel Janman, Behzad Rowshanravan, Gideon Morris Hirschfield et al. · 2021 · Frontiers in Immunology
72. CHIT1 at Diagnosis Reflects Long‐Term Multiple Sclerosis Disease Activity
    Oldoni, Emanuela, Smets, Ide, Mallants, Klara, Vandebergh, Marijne, Van Horebeek, Lies, Poesen, Koen, Dupont, Patrick, Dubois, Bénédicte, Goris, An · 2020 · Annals of Neurology
73. The relative contributions of obesity, vitamin D, leptin, and adiponectin to multiple sclerosis risk: A Mendelian randomization mediation analysis
    Adil Harroud, Despoina Manousaki, Guillaume Butler‐Laporte, Ruth E. Mitchell, George Davey Smith, John Brent Richards, Sergio E. Baranzini · 2021 · Multiple Sclerosis Journal
74. The associations between plasma soluble Trem1 and neurological diseases: a Mendelian randomization study
    Xiaolei Shi, Tao Wei, Yachun Hu, Meng Wang, Yi Tang · 2022 · Journal of Neuroinflammation
75. Not all roads lead to the immune system: the genetic basis of multiple sclerosis severity
    Vilija Jokubaitis, Maria Pia Campagna, Omar Ibrahim, Jim M. Stankovich, Pavlína Kleinová, Fuencisla Matesanz, Daniel Hui, Sara Eichau, Mark Slee, Jeannette Lechner‐Scott et al. · 2022 · Brain
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    Kathryn C. Fitzgerald, Kicheol Kim, Matthew D. Smith, Sean Andrew Aston, Nicholas Fioravante, Alissa Rothman, Stephen C. Krieger, Stacey S. Cofield, Dorlan J. Kimbrough, Pavan Bhargava et al. · 2019 · Brain
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    Annalisa De Silvestri, Cristina Capittini, Giulia Mallucci, Roberto Bergamaschi, Chiara Rebuffi, Annamaria Pasi, M. Martinetti, Carmine Tinelli · 2019 · Disease Markers
78. Population-level variation in enhancer expression identifies disease mechanisms in the human brain
    Pengfei Dong, Gabriel E. Hoffman, Pasha Apontes, Jaroslav M. Bendl, Samir Rahman, Michael B. Fernando, Biao Zeng, James M. Vicari, Wen Zhang, Kiran Girdhar et al. · 2022 · Nature Genetics
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    Daniela Rojo, Louisa Dal Cengio, Anna Badner, Samuel Kim, Noriaki Sakai, Jacob J. Greene, Tess Dierckx, Lindsey Catherine Mehl, Ella C. Eisinger, Julia Ransom et al. · 2023 · Neuron
80. Impact of genetic risk loci for multiple sclerosis on expression of proximal genes in patients
    Tojo James, Magdalena Lindén, Hiromasa Morikawa, Sunjay Jude Fernandes, Sabrina Ruhrmann, Mikael Huss, Maya Brandi, Fredrik Piehl, Maja Jagodic, Jesper N. Tegner et al. · 2018 · Human Molecular Genetics
81. The immunological significance of tumor necrosis factor receptor-associated factors (TRAFs)
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82. Genetic, Environmental and Lifestyle Determinants of Accelerated Telomere Attrition as Contributors to Risk and Severity of Multiple Sclerosis
    Michael Hecker, Jan Bühring, Brit Fitzner, Paulus Stefan Rommer, Uwe Klaus Zettl · 2021 · Biomolecules
83. Multiple sclerosis: two decades of progress
    Bruce A C Cree, Jorge R. Oksenberg, Stephen L Hauser · 2022 · The Lancet Neurology
84. BTK regulates microglial function and neuroinflammation in human stem cell models and mouse models of multiple sclerosis
    Ross C. Gruber, Gregory S. Wirak, Anna S. Blazier, Lan Lee, Michael R. Dufault, Nellwyn Hagan, Nathalie Chrétien, Michael J. LaMorte, Timothy R. Hammond, Agnes Cheong et al. · 2024 · Nature Communications
85. Genetic Architecture of Adaptive Immune System Identifies Key Immune Regulators
    Vasiliki Lagou, Josselyn E. Garcia‐Perez, Ide Smets, Lies Van Horebeek, Marijne Vandebergh, Liye Chen, Klara Mallants, Teresa Prezzemolo, Kelly Hilven, Stéphanie Humblet‐Baron et al. · 2018 · Cell Reports
86. An “Outside-In” and “Inside-Out” Consideration of Complement in the Multiple Sclerosis Brain: Lessons From Development and Neurodegenerative Diseases
    B. Paul Morgan, Jennifer L. Gommerman, Valeria Ramaglia · 2021 · Frontiers in Cellular Neuroscience
87. Genome-wide genetic links between amyotrophic lateral sclerosis and autoimmune diseases
    Li, Chun Yu, Yang, Tian Mi, Ou, Ru Wei, Wei, Qian Qian, Shang, Hui Fang · 2021 · BMC Medicine
88. Monomethyl Fumarate (MMF, Bafiertam) for the Treatment of Relapsing Forms of Multiple Sclerosis (MS)
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    Benjamin M. Jacobs, Thomas R. Taylor, Amine Mohamed Marc Awad, David Baker, Gavin Giovanonni, Alastair John Noyce, Ruth Dobson · 2020 · Brain Communications
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92. ZEB1 promotes pathogenic Th1 and Th17 cell differentiation in multiple sclerosis
    Yuan Qian, Gabriel Arellano, Igal Ifergan, Jean Lin, Caroline K. Snowden, Taehyeung Kim, Jane Joy Thomas, Calvin Law, Tianxia Guan, Roumen D. Balabanov et al. · 2021 · Cell Reports
93. Increased DNA methylation of SLFN12 in CD4+ and CD8+ T cells from multiple sclerosis patients
    Brooke L. Rhead, Ina Skaara Brorson, Tone Berge, Cameron Adams, Hong Quach, Stine Marit Moen, Pål Berg‐Hansen, Elisabeth Gulowsen Celius, Dipen P. Sangurdekar, Paola G. Bronson et al. · 2018 · PLoS ONE
94. Cell Type-Specific Intralocus Interactions Reveal Oligodendrocyte Mechanisms in MS
    Daniel C. Factor, Anna M. Barbeau, Kevin Cameron Allan, Lucille R. Hu, Mayur Madhavan, An T. Hoang, Kathryn E.A. Hazel, Parker A. Hall, Sagar Nisraiyya, Fadi J. Najm et al. · 2020 · Cell
95. Environmental risk factors in multiple sclerosis: bridging Mendelian randomization and observational studies
    Marijne Vandebergh, Nicolas Degryse, Bénédicte Dubois, An Goris · 2022 · Journal of Neurology
96. Deconstructing and targeting the genomic architecture of human neurodegeneration
    Philip L. De Jager, Hyun‐Sik Yang, David Alan Bennett · 2018 · Nature Neuroscience
97. Different epigenetic clocks reflect distinct pathophysiological features of multiple sclerosis
    Eleftheria Theodoropoulou, Lars S. Alfredsson, Fredrik Piehl, Francesco Marabita, Maja Jagodic · 2019 · Epigenomics
98. Disease state prediction from single-cell data using graph attention networks
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99. Multiple sclerosis iPS-derived oligodendroglia conserve their properties to functionally interact with axons and glia in vivo
    Mozafari, Sabah, Starost, Laura, Manot-Saillet, Blandine, Garcia-Diaz, Beatriz, Xu, Yu Kang T., Roussel, Delphine, Levy, Marion J. F., Ottoboni, Linda, Kim, Kee-Pyo, Schöler, Hans R. et al. · 2020 · Science Advances
100. Smoking Attributable Risk in Multiple Sclerosis
     Ali Manouchehrinia, Jesse Huang, Jan A. Hillert · 2022 · Frontiers in Immunology