A proof of concept for structure-based vaccine design targeting RSV in humans

Crank, Michelle C., Ruckwardt, Tracy J., Chen, Man, Morabito, Kaitlyn M., Phung, Emily, Costner, Pamela J., Holman, LaSonji A., Hickman, Somia P. +43 more·2019·Science

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  23. Decreased Persistence of Maternal Antibodies in Infants Who Are HIV Exposed and Uninfected
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  24. Dynamic regulation-based stabilizing mutations are highly effective for designing RSV pre-fusion F mRNA vaccines
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  25. When structural rationales fall short: revisiting the immunogenicity of herpesvirus prefusion and postfusion glycoprotein B
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  27. A six-proline stabilized trimeric spike DNA vaccine induces robust immunity and protects against SARS-CoV-2 delta challenge in K18-hACE2 transgenic mice
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  29. What Makes a Good Vaccine Antigen Target? Defining Key Features and Predicting Candidates in the Staphylococcus aureus Proteome
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  31. Intramuscular self-amplifying RNA and adenoviral RSV vaccines program distinct systemic and respiratory mucosal immune architectures
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  32. From Concept to Clinical Trial: Starting Clinical Trials with a New Vaccine
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