A proof of concept for structure-based vaccine design targeting RSV in humans
Crank, Michelle C., Ruckwardt, Tracy J., Chen, Man, Morabito, Kaitlyn M., Phung, Emily, Costner, Pamela J., Holman, LaSonji A., Hickman, Somia P. +43 more·2019·Science
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- Quantifying the association between neutralising antibodies and protection from RSV disease in infants and adults: A systematic review and meta-analysisAlexandra B. Hogan, Ainslie Mitchell, Eva Stadler, Yuna Chung, Arnold Reynaldi, Karen M Elias, Steffen S. Docken, David S. Khoury, Timothy E. Schlub, Miles P. Davenport et al. · 2026 · medRxiv
- Structure-guided computational design of high-affinity antibodies enables chemiluminescence immunoassay for C-reactive proteinYijian Li, Tonggong Liu, Jingzhe Wang, Xiaona Zhao, Jie Wen, Zhongyan Li, Fuxing Zeng, 顾大勇 · 2026 · Bioorganic Chemistry
- A Rabies Virus Glycoprotein Subunit Vaccine Produced in Pichia pastoris Induces Neutralizing Antibodies in MiceYe Yang, Ruo Mo, Zhuoran Hou, Han Wang, Peng Gang Sun, Ruixi Liu, Tiantian Wang, Bin Zhang, Xuchen Hou, Yongkun Zhao et al. · 2026 · Vaccines
- Engineering strategies and decision frameworks for virus-like particle-based vaccines against infectious diseasesYiyan Liu, Yanan Zhang, Lijuan Liang, Han Zhang, Tianjiao Zhang, Xifeng Rong, Jiying Tan, Youjun Mi · 2026 · Frontiers in Microbiology
- Decreased Persistence of Maternal Antibodies in Infants Who Are HIV Exposed and UninfectedYiwei Jiang, Tessa Goetghebuer, Stefan Embacher, Anaïs Thiriard, Véronique Olislagers, Dansala Welba, Martin Taton, Inès Vu Duc, Katty Renard, Shilpee Sharma et al. · 2026 · The Journal of Infectious Diseases
- Dynamic regulation-based stabilizing mutations are highly effective for designing RSV pre-fusion F mRNA vaccinesShuai Shao, Ze Yuan Dong, Zi Yao Kang, Hao Zhang, Xiang Zheng, Fu Jie Shen, Yu Qin Jin, Zheng Pan, Xin Li, Ning Liu et al. · 2026 · Biochemical and Biophysical Research Communications
- When structural rationales fall short: revisiting the immunogenicity of herpesvirus prefusion and postfusion glycoprotein BJulia Nentwig, Kay Grünewald, Benjamin Vollmer · 2026 · Current Opinion in Virology
- mRNA vaccines against viral pathogens: molecular design, delivery systems, and clinical applicationsWei Xu, Jun Wang, Xueke Liu, Mei Lü, Z K Zhang, Li Li · 2026 · Frontiers in Microbiology
- A six-proline stabilized trimeric spike DNA vaccine induces robust immunity and protects against SARS-CoV-2 delta challenge in K18-hACE2 transgenic miceAytül Gül, Ceren Gül, Tuğba Karakavuk, Muhammet Karakavuk, Hüseyin Can, Hivda Ülbeği-Polat, Müge Serhatlı, Hilal Yazıcı, Şenay KÖM, Arzu Taş Ekiz et al. · 2026 · Biomedicine & Pharmacotherapy
- Malaria serology for surveillance, insights into immunity, and vaccine developmentP. Lim, J. Bernal, Janani Karunarathne, R. Longley · 2026 · Infection and Immunity
- What Makes a Good Vaccine Antigen Target? Defining Key Features and Predicting Candidates in the Staphylococcus aureus ProteomeNadia K. Prasetyo, Ries J. Langley, Fiona Jane Radcliff, Paul P. Gardner · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Protein language model aided library generation for discovery of affinity peptides targeting the respiratory syncytial virus F proteinQiuyang Gong, Qinghong Shi · 2026 · Biochemical Engineering Journal
- Intramuscular self-amplifying RNA and adenoviral RSV vaccines program distinct systemic and respiratory mucosal immune architecturesYao Zhang, Yu Qin, Zhongbing Qi, Qingzhe Yang, Xian Zhang, Shichuan Hu, Yuejun Li, Boduan Xiao, Jianchuan Hu, Ping Cheng · 2026 · EMBO Molecular Medicine
- From Concept to Clinical Trial: Starting Clinical Trials with a New VaccineStephen P. Lockhart, Michele Sausser, William C. Gruber · 2026 · Springer eBooks
- Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)Kayvon Modjarrad, Kena A. Swanson · 2026 · Springer eBooks