The DOI matches its Crossref record; 59 of the 59 references it cites were found in a registry or an index.
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis
Open accessAbstract
Metastasis: A matter of translation?: Solid tumors shed a small number of cancer cells into the bloodstream, some of which are believed to contribute to metastasis. The molecular features that confer these circulating tumor cells (CTCs) with metastatic potential are poorly understood. Ebright et al. studied CTCs from breast cancer patients and found that cells with increased expression levels of certain ribosomal proteins and regulators of translation had greater metastatic capacity in a mouse model (see the Perspective by Ma and Jeffrey). Consistent with this finding, patients with higher levels of this subset of CTCs tended to have a poorer prognosis. Science , this issue p. 1468 ; see also p. 1424
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Self-citationCirculating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis
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Arafeh, R., Shibue, T., Dempster, J. M., Hahn, W. C., & Vazquez, F. (2025) · Nature Reviews Cancer · doi:10.1038/s41568-024-00763-x · Cited by 454
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Specialized Ribosomes in Health and Disease
Miller, S. C., MacDonald, C. C., Kellogg, M. K., Karamysheva, Z. N., & Karamyshev, A. L. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076334 · Cited by 42
Metadata
- Authors
- Ebright, R. Y., Lee, S., Wittner, B. S., Niederhoffer, K. L., Nicholson, B. T., Bardia, A., Truesdell, S., Wiley, D. F., Wesley, B., Li, S., Mai, A., Aceto, N., Vincent-Jordan, N., Szabolcs, A., Chirn, B., Kreuzer, J., Comaills, V., Kalinich, M., Haas, W., Ting, D. T., Toner, M., Vasudevan, S., Haber, D. A., Maheswaran, S., & Micalizzi, D. S.
- Venue
- Science
- Published
- 2020-03-27
- Volume
- 367
- Issue
- 6485
- Pages
- 1468-1473
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W3004434748
- Cited by
- 365
- References
- 59
- FWCI
- 18.13
- Type
- journal article
- Language
- en
- Open access
- green
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- Ebright, R. Y., Lee, S., Wittner, B. S., Niederhoffer, K. L., Nicholson, B. T., Bardia, A., Truesdell, S., Wiley, D. F., Wesley, B., Li, S., Mai, A., Aceto, N., Vincent-Jordan, N., Szabolcs, A., Chirn, B., Kreuzer, J., Comaills, V., Kalinich, M., Haas, W., . . . Micalizzi, D. S. (2020). Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis. Science. https://doi.org/10.1126/science.aay0939
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
