DNA loop extrusion by human cohesin

Davidson, Iain F., Bauer, Benedikt, Goetz, Daniela, Tang, Wen, Wutz, Gordana, Peters, Jan-Michael·2019·Science

Cited by (866)

Items 701–800 of 866

  1. Cohesin extrudes chromatin loop unidirectionally through two modes of mechanisms in human cells
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  2. Cohesin in space and time: architecture and oligomerization in vivo
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  3. Editorial overview: Genome architecture and expression
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  4. The assisting role of Polη in transcription facilitates formation of damage-induced cohesion
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  5. Effects of forced cohesin eviction and retention on X-inactivation and autosomes
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  6. Slow chromatin dynamics enhances promoter accessibility to transcriptional condensates
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  7. Polymer Folding Simulations from Hi-C Data
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  8. A theory of the dynamics of DNA loop initiation in condensin/cohesin complexes
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  9. The loader complex Scc2/4 forms co-condensates with DNA as loading sites for cohesin
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  10. Faculty Opinions recommendation of Loop extrusion as a mechanism for formation of DNA damage repair foci.
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  11. Bioinformatics analysis of multi-omics data elucidates the primary function of Oct4 in gene regulation and pluripotency maintenance
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  12. Chromatin reorganization, signaling responses and non-coding RNA regulators in homeostasis and senescence
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  13. PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome
    Nicole L. Arruda, Audra F. Bryan, Jill M. Dowen · 2022 · Research Square
  14. Formation of the clamped state by Scc2 and DNA overcomes the constraints imposed by zipping-up of the SMC coiled coils on cohesin’s ATPase
    Menelaos Voulgaris, Kim Nasmyth, Madhusudhan Srinivasan · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  15. Cohesin is involved in transcriptional repression of stage-specific genes in the human malaria parasite
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  17. The landscape of the repeated sequences in the human genome
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  18. Involvement of aberrant chromosome architecture and locus-specific vulnerability to DNA methylation epimutations in bovine large offspring syndrome
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  19. Analysis of Chromatin Interaction and Accessibility by Trac-Looping
    Shuai Liu, Qingsong Tang, Keji Zhao · 2023 · Methods in molecular biology
  20. Single Molecule Dynamics of Sister Chromatid Cohesin
    Yoshimi Kinoshita, Tomoko Nishiyama · 2023 · Seibutsu Butsuri
  21. Dependency of 3D chromatin folding on RNA polymerase II at different cell cycle stages
    Nadine Übelmesser · 2023
  22. What AlphaFold tells us about cohesin’s retention on and release from chromosomes
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  23. Activity of MukBEF for chromosome management in E. coli and its inhibition by MatP
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  24. What AlphaFold tells us about cohesin’s retention on and release from chromosomes
    Nasmyth, Kim A., Lee, Byung-Gil, Roig, Maurici B., Löwe, Jan · 2023
  25. Widespread link between DNA-packing density distribution and TAD boundary locations
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  26. Single-Molecule Approaches to Study DNA Condensation
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  27. The endogenous Mtv8 locus and the immunoglobulin repertoire
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  28. 关键生物信号枢纽的细胞原位单分子定位超高分辨率解析
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  29. The plant specific cohesin subunit SYN4 contributes to 3D genome organization
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  30. Additional file 2 of Contribution of variant subunits and associated factors to genome-wide distribution and dynamics of cohesin
    Ana Cuadrado, Daniel Giménez-Llorente, Magali De Koninck, Miguel Ruiz‐Torres, Aleksandar Kojic, Miriam Rodríguez-Corsino, Ana Losada · 2022 · Figshare
  31. Properties of the Ureaplasma parvum SMC protein related to its interaction with DNA
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  32. Interplay between cohesin and TORC1 links chromosome segregation and gene expression to environmental changes
    Dorian Besson, Sabine Vaur, Stéphanie Vazquez, Sylvie Tournier, Yannick Gachet, Adrien Birot, Stéphane Claverol, Adèle L. Marston, Anastasios E. Damdimopoulos, Karl Ekwall et al. · 2026 · eLife
  33. Motor domain of condensin and step formation in extruding loop of DNA
    Y.-C. Chou · 2024 · Journal of biological physics (Print)
  34. In through the out door: A loop‐binding‐first model for topological cohesin loading
    Nick Rhind · 2024 · BioEssays
  35. Promoter- and Enhancer-Dependent Cohesin Loading Initiates Chromosome Looping to Fold Tcrb Loci for Long-Range Recombination
    Brittney M. Allyn, Katharina E. Hayer, Clément Oyeniran, Vincent K. Nganga, Kyutae David Lee, Ahmet Saçan, Eugene M. Oltz, Craig H. Bassing · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  36. Cohesin-dependent loop extrusion: molecular mechanics and role in cell physiology
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  37. Studying the structure and function of nucleosomes by atomic force microscopy
    Alexander A. Ukraintsev, Mikhail M. Kutuzov, Olga I. Lavrik · 2024 · Biochemistry (Moscow)
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  39. Polaris: a universal tool for chromatin loop annotation in bulk and single-cell Hi-C data
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  42. Interactions of the Escherichia coli SMC-like RecN protein to different forms of DNA revealed at the single-molecule level using optical tweezers
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  43. Mean Pairwise Distances in Rouse Polymer Subject to Fast Loop Extrusion
    I. Nikitin, Nikolay Masnev, Sergey Belan · 2025 · Journal of Experimental and Theoretical Physics Letters
  44. SMC complex unidirectionally translocates DNA by coupling segment capture with an asymmetric kleisin path
    Yamauchi, Masataka, Brandani, Giovanni Bruno, Terakawa, Tsuyoshi, Takada, Shoji · 2026 · eLife
  45. Calyculin A Induces Premature Chromosome Condensation and Chromatin Compaction in G 1 -Phase HeLa Cells without Histone H1 Phosphorylation
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  46. DNA methylation insulates genic regions from CTCF loops near nuclear speckles
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  47. The emerging sequence grammar of 3D genome organisation
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  48. MIA-Jet: Multi-scale Identification Algorithm of Chromatin Jets
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  49. Criticality-driven enhancer-promoter dynamics in Drosophila chromosomes
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  50. Criticality-driven enhancer-promoter dynamics in Drosophila chromosomes
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  52. Single-Molecule Analyses of Human Cohesin Complex
    Yoshimi Kinoshita, Tomoko Nishiyama · 2025 · Methods in molecular biology
  53. Visualizing Binding of Single SMC Complexes to DNA Substrates Using Combinational Optical Tweezers and Fluorescence Microscopy
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  54. High-Resolution Chromosome Conformation Capture Method to Study Archaeal SMC Complexes
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  55. Cohesin acetylation and ATPase activity control cohesion and loop architecture through distinct mechanisms
    Lorenzo Costantino, Tiantian Ye, Kevin Boardman, Siheng Xiang, Jonathan Luo, Yudi Mu, Wenxiu Ma, Douglas E. Koshland · 2026 · Proceedings of the National Academy of Sciences
  56. Yeast condensin acts as a transient intermolecular crosslinker in entangled DNA
    Filippo Conforto, Antonio Valdés, W. Vanderlinden, Davide Michieletto · 2025 · Nucleic Acids Research
  57. Interplay between cohesin and TORC1 links chromosome segregation and gene expression to environmental changes
    Dorian Besson, Sabine Vaur, Stéphanie Vazquez, Sylvie Tournier, Yannick Gachet, Adrien Birot, Stéphane Claverol, Adèle L. Marston, Anastasios E. Damdimopoulos, Karl Ekwall et al. · 2025 · eLife
  58. Condensin chromatin association is regulated by SMC head and hinge engagement and phosphorylation
    Catrina Miles, Miao Yu, Nicola E. Minchell, Stephanie A. Schalbetter, Antony W. Oliver, Steve M. M. Sweet, Jonathan Baxter · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  59. Conserved 3D genome reorganization during DNA repair
    Veysel Oğulcan Kaya, Ogün Adebalı, Hanspeter Naegeli, Michelle N. Yancoskie · 2025 · Life Science Alliance
  60. Contact networks encode the ATP-induced dynamic structural asymmetry of condensin head domains
    C. Xu, Xiakun Chu · 2025 · The Journal of Chemical Physics
  61. Additional file 1 of Mustache: multi-scale detection of chromatin loops from Hi-C and Micro-C maps using scale-space representation
    Abbas Roayaei Ardakany, Halil Tuvan Gezer, Lonardi, Stefano, Ay, Ferhat · 2020 · Figshare
  62. Additional file 1 of Contribution of variant subunits and associated factors to genome-wide distribution and dynamics of cohesin
    Ana Cuadrado, Daniel Giménez-Llorente, Magali De Koninck, Miguel Ruiz‐Torres, Aleksandar Kojic, Miriam Rodríguez-Corsino, Ana Losada · 2022 · Figshare
  63. Additional file 4 of RAD21 is the core subunit of the cohesin complex involved in directing genome organization
    Yuao Sun, Xu, Xin, Zhao, Wenxue, Zhang, Yu, Chen, Keyang, Li, Yongzheng, Wang, Xiaotian, Zhang, Mengling, Boxin Xue, Yu, Wanting et al. · 2024 · Figshare
  64. Additional file 1 of Mechanisms of enhancer action: the known and the unknown
    Panigrahi, Anil, Bert W. O’Malley · 2021 · Figshare
  65. Additional file 2 of CTCF and cohesin promote focal detachment of DNA from the nuclear lamina
    Tom van Schaik, Ning Qing Liu, Stefano Giustino Manzo, Daan Peric‐Hupkes, Elzo de Wit, Bas van Steensel · 2022 · Figshare
  66. Additional file 1 of PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome
    Nicole L. Arruda, Audra F. Bryan, Jill M. Dowen · 2022 · Figshare
  67. Additional file 3 of Contribution of variant subunits and associated factors to genome-wide distribution and dynamics of cohesin
    Ana Cuadrado, Giménez-Llorente, Daniel, Magali De Koninck, Miguel Ruiz‐Torres, Aleksandar Kojic, Miriam Rodríguez-Corsino, Ana Losada · 2022 · Figshare
  68. Additional file 1 of Sensitivity of cohesin–chromatin association to high-salt treatment corroborates non-topological mode of loop extrusion
    Arkadiy K. Golov, Anastasia Golova, Alexey A. Gavrilov, Sergey V. Razin · 2021 · Figshare
  69. Additional file 2 of PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome
    Nicole L. Arruda, Audra F. Bryan, Jill M. Dowen · 2022 · Figshare
  70. Additional file 2 of RAD21 is the core subunit of the cohesin complex involved in directing genome organization
    Yuao Sun, Xu, Xin, Wenxue Zhao, Zhang, Yu, Chen, Keyang, Li, Yongzheng, Wang, Xiaotian, Zhang, Mengling, Boxin Xue, Yu, Wanting et al. · 2024 · Figshare
  71. Additional file 2 of HiCognition: a visual exploration and hypothesis testing tool for 3D genomics
    Christoph C. H. Langer, Michael Mitter, Roman R. Stocsits, Daniel W. Gerlich · 2023 · Figshare
  72. Additional file 3 of CTCF and cohesin promote focal detachment of DNA from the nuclear lamina
    Tom van Schaik, Ning Qing Liu, Stefano Giustino Manzo, Daan Peric‐Hupkes, Elzo de Wit, Bas van Steensel · 2022 · Figshare
  73. Additional file 2 of Sensitivity of cohesin–chromatin association to high-salt treatment corroborates non-topological mode of loop extrusion
    Arkadiy K. Golov, Anastasia Golova, Alexey A. Gavrilov, Sergey V. Razin · 2021 · Figshare
  74. Additional file 1 of CTCF and cohesin promote focal detachment of DNA from the nuclear lamina
    Tom van Schaik, Ning Qing Liu, Stefano Giustino Manzo, Daan Peric‐Hupkes, Elzo de Wit, Bas van Steensel · 2022 · Figshare
  75. Additional file 2 of Mustache: multi-scale detection of chromatin loops from Hi-C and Micro-C maps using scale-space representation
    Abbas Roayaei Ardakany, Halil Tuvan Gezer, Lonardi, Stefano, Ay, Ferhat · 2020 · Figshare
  76. Additional file 1 of HiCognition: a visual exploration and hypothesis testing tool for 3D genomics
    Christoph C. H. Langer, Michael Mitter, Roman R. Stocsits, Daniel W. Gerlich · 2023 · Figshare
  77. Additional file 5 of Contribution of variant subunits and associated factors to genome-wide distribution and dynamics of cohesin
    Ana Cuadrado, Daniel Giménez-Llorente, Magali De Koninck, Miguel Ruiz‐Torres, Aleksandar Kojic, Miriam Rodríguez-Corsino, Ana Losada · 2022 · Figshare
  78. Additional file 3 of RAD21 is the core subunit of the cohesin complex involved in directing genome organization
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  79. Additional file 1 of RAD21 is the core subunit of the cohesin complex involved in directing genome organization
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  80. Additional file 2 of Chromosomal localization of cohesin is differentially regulated by WIZ, WAPL, and G9a
    Megan Justice, Audra F. Bryan, Juanita C. Limas, Jeanette Gowen Cook, Jill M. Dowen · 2022 · Figshare
  81. Additional file 4 of Contribution of variant subunits and associated factors to genome-wide distribution and dynamics of cohesin
    Ana Cuadrado, Daniel Giménez-Llorente, Magali De Koninck, Miguel Ruiz‐Torres, Aleksandar Kojic, Miriam Rodríguez-Corsino, Ana Losada · 2022 · Figshare
  82. Additional file 1 of The SAGA histone acetyltransferase module targets SMC5/6 to specific genes
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  83. SMC complex unidirectionally translocates DNA by coupling segment capture with an asymmetric kleisin path
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  84. Altered Cohesin Dynamics During Cellular Differentiation
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  91. Role of nuclear ATPases in nuclear mechanics and cell migration through confined spaces: Opposite effects of BRG1 and cohesin
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  93. Clinical, in vitro, and in vivo evidence of WAPL as a novel cohesinopathy gene and phenotypic driver of 10q22.3q23.2 genomic disorder
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  95. SMC Motor Proteins Operate at the Near-Minimal Forces for DNA Loop Extrusion
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  97. Impaired cohesin loading disrupts pancreatic differentiation by Polycomb-driven chromatin rewiring and loop collapse
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