Human cohesin compacts DNA by loop extrusion

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Items 501–600 of 705

  1. Pioneer transcription factors direct tissue-specific cohesin chromatin entry and three-dimensional genome organization
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  3. Reeling it in: how DNA topology drives loop extrusion by condensin
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  4. Prediction of CTCF loop anchor based on machine learning
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  9. Bridging scales in chromatin organization: Computational models of loop formation and their implications for genome function.
    Shingo Tsukamoto, Mohammad R. K. Mofrad · 2025 · Journal of Chemical Physics
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    Hyun Jung Oh, Priyojit Das, Roy Blum, Andrea J. Kriz, Hun-Goo Lee, Yong-Woo Lee, Jeannie T. Lee · 2025 · Developmental Cell
  11. The role of macromolecular crowders in the formation and compaction of the Escherichia coli nucleoid
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  12. Mechanism of DNA entrapment by a loop-extruding Wadjet SMC motor
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  13. Regulation and dysregulation of spatial chromatin structure in the central nervous system
    Yuki Fujita · 2021 · Anatomical Science International
  14. Functional Coupling between DNA Replication and Sister Chromatid Cohesion Establishment
    Ana Boavida, Diana Santos, Mohammad Mahtab, Francesca M. Pisani · 2021 · International Journal of Molecular Sciences
  15. Biology of Chromatin
    Renato Paro, Ueli Grossniklaus, Raffaella Santoro, Anton Wutz · 2021 · Learning materials in biosciences
  16. Chromatin stability generated by stochastic binding and unbinding of cross-linkers at looping sites revealed by Markov models
    Andrea Papale, David Holcman · 2021 · Physical Biology
  17. Single amino acid substitutions in hydrophobic cores at a head-coiled coil junction region of cohesin facilitate its release of DNA during anaphase
    Xingya Xu, R. Kanai, Li Wang, Mitsuhiro Yanagida · 2022 · Open Biology
  18. Loop competition and extrusion model predicts CTCF interaction specificity
    Xi Wang, M Beer · 2021 · RePEc: Research Papers in Economics
  19. Theory and Simulations of condensin mediated loop extrusion in DNA
    Ryota Takaki, Atreya Dey, Guang Shi, Dave Thirumalai · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  20. Loop competition and extrusion model predicts CTCF interaction specificity
    Wang Xi, M Beer · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  21. The organizer of chromatin topology RIF1 ensures cellular resilience to DNA replication stress
    Cyril Ribeyre, Rana Lebdy, Julie Patouillard, Marion Larroque, Raghida Abou Merhi, Christian Larroque, Angelos Constantinou · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  22. Context-dependent 3D genome regulation by cohesin and related factors
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  23. Cohesin regulates promoter-proximal pausing of RNA Polymerase II by limiting recruitment of super elongation complex
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  24. Programmed DNA breaks drive chromatin reconfiguration and facilitate transcriptional potentiation at neuronal early response genes
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  25. SMCHD1 compacts DNA directly in an ATP-regulated manner
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  27. High-throughput in silico screen uncovers key regulators of 3D genome architecture
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  28. NIPBL-mediated 3D genome folding translates enhancer priming into gene activation and safeguards lineage fidelity during embryonic transitions
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  30. Molecular dynamics simulations of human cohesin subunits identify DNA binding sites and their potential roles in DNA loop extrusion
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  31. Site-to-site mutational dissection of fission yeast cohesin reveals its dynamics
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  32. Ectopic Recruitment of the CTCF N-Terminal Domain with Two Proximal Zinc-Finger Domains as a Tool for 3D Genome Engineering
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  35. Promoter- and enhancer-dependent cohesin loading initiates chromosome looping to fold Tcrb loci for long-range recombination
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  39. CTCF couples long-range loop extrusion and diffusion to mediate a diverse Igκ repertoire
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  40. Early resolution of sister chromatids during C. elegans meiosis
    Antonia Hamrick, Ofer Rog · 2025 · The Journal of Cell Biology
  41. Sororin locks the DNA-exit gate of cohesin to preserve sister-chromatid cohesion
    Qinfu Chen, Xueying Yuan, M. G. Shi, Xinyu Zhou, Shukai Zhu, Weiguo Lu, Haiyan Yan, Fangwei Wang · 2026 · Nature Communications
  42. RNAPII and DNA supercoiling regulate cohesin engagement in neurons
    Morgan Crewe, Ilse Delint‐Ramírez, Omar Halawa, Lance Heady, Ram Madabhushi · 2026 · Nucleic Acids Research
  43. Folding a broken genome: the versatile roles of cohesin in genome maintenance
    Alberto Marín-González, Taekjip Ha · 2026 · Nature Reviews Genetics
  44. Chromosome Architecture Defined by the Meiosis-Specific Cohesin in Mammalian Germ Cells
    Kei‐ichiro Ishiguro, Yasuhiro Fujiwara · 2026 · Advances in experimental medicine and biology
  45. A splicing factor-cohesin association links RNA processing to cohesin-dependent genome folding
    Tao Wu, Shuang Cui, Zhiyu Zhang, Zihang Yin, Yefan Wang, Hewei Xu, Heng Zhang, Wuming Wang, Wenchao Gu, Ya Guo · 2026 · Cell Reports
  46. Deficiency of Polη in Saccharomyces cerevisiae reveals the impact of transcription on damage-induced cohesion
    Pei‐Shang Wu, Jan Grosser, Donald P. Cameron, Laura Baranello, Lena Ström · 2021 · PLoS Genetics
  47. Cohesin puts a break on distal homology hunt
    Argyris Papantonis, Vassilis Roukos · 2021 · Nature Cell Biology
  48. Cohesin organization, dynamics, and subdomain functions revealed by genetic suppressor screening
    Xingya Xu, Mitsuhiro Yanagida · 2023 · Proceedings of the Japan Academy Series B
  49. Mechanism and Regulation of Immunoglobulin Class Switch Recombination
    Fei‐Long Meng, Lekha Nair, Keith Conrad Fernandez, Uttiya Basu, Jayanta Chaudhuri · 2024 · Elsevier eBooks
  50. Genome 3D Structure Generated through Chromatin Movement
    Shin Fujishiro, Masaki Sasai · 2024 · Seibutsu Butsuri
  51. STAG2-RAD21 complex: A unidirectional DNA ratchet mechanism in loop extrusion
    David Ros‐Pardo, Paulino Gómez‐Puertas, Íñigo Marcos‐Alcalde · 2024 · International Journal of Biological Macromolecules
  52. Cell biology: Converging paths to cohesion
    Roel Oldenkamp, Benjamin D. Rowland · 2024 · Current Biology
  53. The cohesin complex: structure and principles of interaction with dna
    Arkadiy K. Golov, Alexey A. Gavrilov · 2024 · Biochemistry (Moscow)
  54. CTCF-anchored chromatin loop dynamics during human meiosis
    Vera B. Kaiser, Colin A M Semple · 2025 · BMC Biology
  55. Three-dimensional genome rewiring during the development of antibody-secreting cells
    Wing Fuk Chan, Timothy M. Johanson, Rhys S. Allan · 2020 · Biochemical Society Transactions
  56. Condensin: The Little Motor Protein that Could
    Anton A. Goloborodko · 2020 · Molecular Cell
  57. Extrusion of chromatin loops by a composite loop extrusion factor
    Hao Yan, Ivan Vladimirovich Surovtsev, Jessica F. Williams, Mary Lou P. Bailey, Megan C. King, S. G. J. Mochrie · 2021 · Physical review. E
  58. Towards a Structural Mechanism for Sister Chromatid Cohesion Establishment at the Eukaryotic Replication Fork
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  59. BET proteins loop and compartmentalize the 3D genome
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  60. Computational and experimental analyses of mitotic chromosome formation pathways in fission yeast
    Tereza Gerguri, Xiao Fu, Yasutaka Kakui, Bhavin S. Khatri, Christopher Barrington, Paul A. Bates, Frank Uhlmann · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  61. ATP dependent DNA transport within cohesin: Scc2 clamps DNA on top of engaged heads while Scc3 promotes entrapment within the SMC-kleisin ring
    James Collier, Byung‐Gil Lee, Maurici Brunet Roig, Stanislav Yatskevich, Naomi J Petela, Jean Metson, Menelaos Voulgaris, Andres Gonzalez Llamazares, Jan Löwe, Kim Nasmyth · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  62. Rad21 is the core subunit of the cohesin complex involved in directing genome organization
    Yujie Sun, Yuao Sun, Xin Xu, Wenxue Zhao, Yu Zhang, Keyang Chen, Yongzheng Li, Xiaotian Wang, Mengling Zhang, Boxin Xue et al. · 2021 · Research Square
  63. The RAG1 N-terminal region regulates the efficiency and pathways of synapsis for V(D)J recombination
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  64. Hi-TrAC reveals fine-scale chromatin structures organized by transcription factors
    Shuai Liu, Yaqiang Cao, Kairong Cui, Qingsong Tang, Keji Zhao · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  65. DNA capture and loop extrusion dynamics by cohesin-NIPBL
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  66. Different NIPBL requirements of cohesin-STAG1 and cohesin-STAG2
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  68. BRWD1 orchestrates chromatin topology by converting static to dynamic cohesin complexes
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  71. RNA Pol II antagonises mitotic chromatin folding and chromosome segregation by condensin
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  73. Replisomes restrict SMC-mediated DNA-loop extrusion in vivo
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  83. STAG2 loss-of-function affects short-range genomic contacts and modulates urothelial differentiation in bladder cancer cells
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  85. The assisting role of Polη in transcription facilitates formation of damage-induced cohesion
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  86. Effects of forced cohesin eviction and retention on X-inactivation and autosomes
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  97. Formation of the clamped state by Scc2 and DNA overcomes the constraints imposed by zipping-up of the SMC coiled coils on cohesin’s ATPase
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