Human cohesin compacts DNA by loop extrusion
Cited by (705)
Items 501–600 of 705
- Pioneer transcription factors direct tissue-specific cohesin chromatin entry and three-dimensional genome organizationSong Wang, Xianglin Zhang, Tianwei Jia, Wenzheng Wang, Xiaoyu Liu, Hui Lin, Haoran Pan, Jinyi Zhang, Dongqing Li, Lin Zhang et al. · 2026 · Nature Genetics
- Structure and function of the centromere and inner kinetochoreRachel R. Brown, Pim J. Huis in ’t Veld, Andrea Musacchio, Aaron F. Straight · 2026 · Nature Reviews Molecular Cell Biology
- Reeling it in: how DNA topology drives loop extrusion by condensinDomenic N. Narducci, Anders S. Hansen · 2022 · Nature Structural & Molecular Biology
- Prediction of CTCF loop anchor based on machine learningXiao Li Zhang, Wen Zhu, Huimin Sun, Yijie Ding, Li Liu · 2023 · Frontiers in Genetics
- Identification of STAG2-Mutant Bladder Cancers by ImmunohistochemistryYoungrok Park, Alana Lelo, Brent T. Harris, Deborah L. Berry, Krysta M. Chaldekas, Jung-Sik Kim, Todd A. Waldman · 2023 · Methods in molecular biology
- Toward a comprehensive view of gene architecture during transcriptionMarcus A. Woodworth, Melike Lakadamyali · 2024 · Current Opinion in Genetics & Development
- 3D epigenomics and 3D epigenopathiesKyunghwan Lee, J. W. Kim, Ji Hun Kim · 2024 · BMB Reports
- Studying Structure and Functions of Nucleosomes with Atomic Force MicroscopyAlexander A. Ukraintsev, Mikhail M. Kutuzov, Olga I. Lavrik · 2024 · Biochemistry (Moscow)
- Bridging scales in chromatin organization: Computational models of loop formation and their implications for genome function.Shingo Tsukamoto, Mohammad R. K. Mofrad · 2025 · Journal of Chemical Physics
- Jpx RNA controls Xist induction through spatial reorganization of the mouse X-inactivation centerHyun Jung Oh, Priyojit Das, Roy Blum, Andrea J. Kriz, Hun-Goo Lee, Yong-Woo Lee, Jeannie T. Lee · 2025 · Developmental Cell
- The role of macromolecular crowders in the formation and compaction of the Escherichia coli nucleoidJ. Männik, J. Männik, C. Amarasinghe, Mu-Hung Chang, Maxim O. Lavrentovich · 2025 · EcoSal Plus
- Mechanism of DNA entrapment by a loop-extruding Wadjet SMC motorFlorian Roisné-Hamelin, Hon Wing Liu, N. Marechal, Emiko Uchikawa, Alexandre Durand, Stephan Gruber · 2025 · Molecular Cell
- Regulation and dysregulation of spatial chromatin structure in the central nervous systemYuki Fujita · 2021 · Anatomical Science International
- Functional Coupling between DNA Replication and Sister Chromatid Cohesion EstablishmentAna Boavida, Diana Santos, Mohammad Mahtab, Francesca M. Pisani · 2021 · International Journal of Molecular Sciences
- Biology of ChromatinRenato Paro, Ueli Grossniklaus, Raffaella Santoro, Anton Wutz · 2021 · Learning materials in biosciences
- Chromatin stability generated by stochastic binding and unbinding of cross-linkers at looping sites revealed by Markov modelsAndrea Papale, David Holcman · 2021 · Physical Biology
- Single amino acid substitutions in hydrophobic cores at a head-coiled coil junction region of cohesin facilitate its release of DNA during anaphaseXingya Xu, R. Kanai, Li Wang, Mitsuhiro Yanagida · 2022 · Open Biology
- Loop competition and extrusion model predicts CTCF interaction specificityXi Wang, M Beer · 2021 · RePEc: Research Papers in Economics
- Theory and Simulations of condensin mediated loop extrusion in DNARyota Takaki, Atreya Dey, Guang Shi, Dave Thirumalai · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Loop competition and extrusion model predicts CTCF interaction specificityWang Xi, M Beer · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- The organizer of chromatin topology RIF1 ensures cellular resilience to DNA replication stressCyril Ribeyre, Rana Lebdy, Julie Patouillard, Marion Larroque, Raghida Abou Merhi, Christian Larroque, Angelos Constantinou · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Context-dependent 3D genome regulation by cohesin and related factorsRyuichiro Nakato, Toyonori Sakata, Jiankang Wang, Luís Augusto Eijy Nagai, Gina Miku Oba, Masashige Bando, Katsuhiko Shirahige · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Cohesin regulates promoter-proximal pausing of RNA Polymerase II by limiting recruitment of super elongation complexShoin Tei, Toyonori Sakata, Atsunori Yoshimura, Toyoaki Natsume, Masato T. Kanemaki, Masashige Bando, Katsuhiko Shirahige · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Programmed DNA breaks drive chromatin reconfiguration and facilitate transcriptional potentiation at neuronal early response genesLance Heady, Richard Rueda, Amir Segev, Krystal G. Morton, Ram Madabhushi · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- SMCHD1 compacts DNA directly in an ATP-regulated mannerJ.D. Ng, Xiaodan Zhao, Xuyao Liu, Aghil Soman, Lars Nordenskiöld, Jie Yan, Shifeng Xue · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Epstein-Barr Virus Encoded lncRNAs Control the Viral Lytic SwitchZhi‐Xuan Li, Yifei Liao, Weiyue Ding, Davide Maestri, Scott L. Grote, Gabriel A. Romero Agosto, Laura A. Murray‐Nerger, Rui Guo, Bo Zhao, Silvi Rouskin et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- High-throughput in silico screen uncovers key regulators of 3D genome architectureJiangshan Bai, Qingji Lyu, Jimin Tan, Robbyn Issner, Bailey Tischer, Hanqing Liu, Viraat Y. Goel, Xinyu Ling, B Bernstein, Aristotelis Tsirigos et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- NIPBL-mediated 3D genome folding translates enhancer priming into gene activation and safeguards lineage fidelity during embryonic transitionsZhangli Ni, Xiaohui Ma, Stephanie Do, Lingling Cheng, Rachel A. Glenn, Thomas Vierbuchen, Alexandros Pertsinidis · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- The first embryo, the origin of cancer and animal phylogeny. V. Cancer stem cells as the unifying biomechanical principle between embryology and oncologyJaime Cofré · 2024 · Mechanobiology in Medicine
- Molecular dynamics simulations of human cohesin subunits identify DNA binding sites and their potential roles in DNA loop extrusionGu, Chenyang, Takada, Shoji, Brandani, Giovanni B., Terakawa, Tsuyoshi · 2025 · PLOS Computational Biology
- Site-to-site mutational dissection of fission yeast cohesin reveals its dynamicsWei Dong Qi, Li Wang, Yichen Zhang, Saidaiguli Abulimiti, Jie Wang, Xingya Xu · 2025 · G3 Genes Genomes Genetics
- Ectopic Recruitment of the CTCF N-Terminal Domain with Two Proximal Zinc-Finger Domains as a Tool for 3D Genome EngineeringEugenia A. Tiukacheva, Artem V. Luzhin, Natalia A. Kruglova, Anastasia S. Shtompel, Grigorii Antonov, Anna V. Tvorogova, Yegor S Vassetzky, Sergey V. Ulianov, Sergey V. Razin · 2025 · International Journal of Molecular Sciences
- 3D Genome Engineering: Current Advances and Therapeutic Opportunities in Human DiseasesXing Jiang, Xiaoli Wang, Song Shen, Shangguo Hou, Yu Chen · 2025 · Research
- Submolecular video-imaging of the Smc5/6 complex topologically bound to DNAKenichi Umeda, Yumiko Kurokawa, Noriyuki Kodera, Yasuto Murayama · 2026 · Nature Communications
- Promoter- and enhancer-dependent cohesin loading initiates chromosome looping to fold Tcrb loci for long-range recombinationBrittney M. Allyn, Katharina E. Hayer, Clément Oyeniran, Vincent K. Nganga, Kyutae David Lee, Ahmet Saçan, Eugene M. Oltz, Craig H. Bassing · 2025 · Cell Reports
- Probing the effect of PEG-DNA interactions and buffer viscosity on tethered DNA in shear flowFatema Tuz Zohra, Huda Al-Zuhairi, Jefferson Reinoza, HyeongJun Kim, Andreas Hanke · 2025 · PLoS ONE
- Distinct and compensatory roles of STAG1 and STAG2 in post-mitotic genome refoldingManzhu Wang, Yabing Zhang, Fengnian Shan, Chongren Pei, Fuhai Liu, Sijian Xia, Lirong Shu, Bicheng Li, Dannan Jing, Yongjia Weng et al. · 2026 · Nature Communications
- Visualizing genetic information flow in space and timeKaijin Chen, Kun Zhao, Yihan Wan · 2025 · Science China Life Sciences
- CTCF couples long-range loop extrusion and diffusion to mediate a diverse Igκ repertoireEmma L. Bush, Brigette Berke-Reynolds, Kaitlyn M. Hutchins, Xinrui Yu, Jorge A. Colón-Rosado, Fu‐Jung Chang, John Curran, Jiaxin Yang, Liangliang Sun, Jianrong Wang et al. · 2025 · Nature Communications
- Early resolution of sister chromatids during C. elegans meiosisAntonia Hamrick, Ofer Rog · 2025 · The Journal of Cell Biology
- Sororin locks the DNA-exit gate of cohesin to preserve sister-chromatid cohesionQinfu Chen, Xueying Yuan, M. G. Shi, Xinyu Zhou, Shukai Zhu, Weiguo Lu, Haiyan Yan, Fangwei Wang · 2026 · Nature Communications
- RNAPII and DNA supercoiling regulate cohesin engagement in neuronsMorgan Crewe, Ilse Delint‐Ramírez, Omar Halawa, Lance Heady, Ram Madabhushi · 2026 · Nucleic Acids Research
- Folding a broken genome: the versatile roles of cohesin in genome maintenanceAlberto Marín-González, Taekjip Ha · 2026 · Nature Reviews Genetics
- Chromosome Architecture Defined by the Meiosis-Specific Cohesin in Mammalian Germ CellsKei‐ichiro Ishiguro, Yasuhiro Fujiwara · 2026 · Advances in experimental medicine and biology
- A splicing factor-cohesin association links RNA processing to cohesin-dependent genome foldingTao Wu, Shuang Cui, Zhiyu Zhang, Zihang Yin, Yefan Wang, Hewei Xu, Heng Zhang, Wuming Wang, Wenchao Gu, Ya Guo · 2026 · Cell Reports
- Deficiency of Polη in Saccharomyces cerevisiae reveals the impact of transcription on damage-induced cohesionPei‐Shang Wu, Jan Grosser, Donald P. Cameron, Laura Baranello, Lena Ström · 2021 · PLoS Genetics
- Cohesin puts a break on distal homology huntArgyris Papantonis, Vassilis Roukos · 2021 · Nature Cell Biology
- Cohesin organization, dynamics, and subdomain functions revealed by genetic suppressor screeningXingya Xu, Mitsuhiro Yanagida · 2023 · Proceedings of the Japan Academy Series B
- Mechanism and Regulation of Immunoglobulin Class Switch RecombinationFei‐Long Meng, Lekha Nair, Keith Conrad Fernandez, Uttiya Basu, Jayanta Chaudhuri · 2024 · Elsevier eBooks
- Genome 3D Structure Generated through Chromatin MovementShin Fujishiro, Masaki Sasai · 2024 · Seibutsu Butsuri
- STAG2-RAD21 complex: A unidirectional DNA ratchet mechanism in loop extrusionDavid Ros‐Pardo, Paulino Gómez‐Puertas, Íñigo Marcos‐Alcalde · 2024 · International Journal of Biological Macromolecules
- Cell biology: Converging paths to cohesionRoel Oldenkamp, Benjamin D. Rowland · 2024 · Current Biology
- The cohesin complex: structure and principles of interaction with dnaArkadiy K. Golov, Alexey A. Gavrilov · 2024 · Biochemistry (Moscow)
- CTCF-anchored chromatin loop dynamics during human meiosisVera B. Kaiser, Colin A M Semple · 2025 · BMC Biology
- Three-dimensional genome rewiring during the development of antibody-secreting cellsWing Fuk Chan, Timothy M. Johanson, Rhys S. Allan · 2020 · Biochemical Society Transactions
- Condensin: The Little Motor Protein that CouldAnton A. Goloborodko · 2020 · Molecular Cell
- Extrusion of chromatin loops by a composite loop extrusion factorHao Yan, Ivan Vladimirovich Surovtsev, Jessica F. Williams, Mary Lou P. Bailey, Megan C. King, S. G. J. Mochrie · 2021 · Physical review. E
- Towards a Structural Mechanism for Sister Chromatid Cohesion Establishment at the Eukaryotic Replication ForkSarah S. Henrikus, Alessandro Costa · 2021 · Biology
- BET proteins loop and compartmentalize the 3D genomeKyle P. Eagen · 2022 · Nature Genetics
- Computational and experimental analyses of mitotic chromosome formation pathways in fission yeastTereza Gerguri, Xiao Fu, Yasutaka Kakui, Bhavin S. Khatri, Christopher Barrington, Paul A. Bates, Frank Uhlmann · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- ATP dependent DNA transport within cohesin: Scc2 clamps DNA on top of engaged heads while Scc3 promotes entrapment within the SMC-kleisin ringJames Collier, Byung‐Gil Lee, Maurici Brunet Roig, Stanislav Yatskevich, Naomi J Petela, Jean Metson, Menelaos Voulgaris, Andres Gonzalez Llamazares, Jan Löwe, Kim Nasmyth · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Rad21 is the core subunit of the cohesin complex involved in directing genome organizationYujie Sun, Yuao Sun, Xin Xu, Wenxue Zhao, Yu Zhang, Keyang Chen, Yongzheng Li, Xiaotian Wang, Mengling Zhang, Boxin Xue et al. · 2021 · Research Square
- The RAG1 N-terminal region regulates the efficiency and pathways of synapsis for V(D)J recombinationHA Beilinson, RA Glynn, AD Yadavalli, J Xiao, Elizabeth Corbett, Huseyin Saribasak, R Arya, Charline Miot, A Bhattacharyya, JM Jones et al. · 2021 · immuneACCESS
- Hi-TrAC reveals fine-scale chromatin structures organized by transcription factorsShuai Liu, Yaqiang Cao, Kairong Cui, Qingsong Tang, Keji Zhao · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- DNA capture and loop extrusion dynamics by cohesin-NIPBLParminder Kaur, Zhu-Bing Shi, Xiao-Tong Lu, Hong-Shan Zhang, I. Finkelstein, Y. Tao, Hong-Tao Yu, Hong Wang · 2022 · bioRxiv
- Different NIPBL requirements of cohesin-STAG1 and cohesin-STAG2Dácil Alonso Gil, Ana Cuadrado, Daniel Giménez-Llorente, Miriam Rodríguez-Corsino, Ana Losada · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Nanofluidic Device for Manipulation and Modification of DNA by ProteinsSaroj Dangi, Ming Liu, Zubair Azad, Preston J. Countryman, Maedeh Roushan, Gideon I. Livshits, Parminder Kaur, Hai Pan, Zhubing Shi, Ariana C. Detwiler et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- BRWD1 orchestrates chromatin topology by converting static to dynamic cohesin complexesMalay Mandal, Mark Maienschein‐Cline, Yeguang Hu, Azam Mohsin, Margaret Veselits, Nathaniel E. Wright, Michael K. Okoreeh, Young me Yoon, Jacob Veselits, Katia Georgopoulos et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- What AlphaFold tells us about cohesin’s retention on and release from chromosomes2023
- What AlphaFold tells us about cohesin’s retention on and release from chromosomesKim Nasmyth, Byung‐Gil Lee, Maurici Brunet Roig, Jan Löwe · 2023 · eLife
- RNA Pol II antagonises mitotic chromatin folding and chromosome segregation by condensinJérémy Lebreton, Léonard Colin, Elodie Chatre, P. Bernard · 2023 · bioRxiv
- STAG2 mutations regulate 3D genome organization, chromatin loops, and Polycomb signaling in glioblastoma multiformeTodd A. Waldman, Jun-Sik Kim, Wanying Xu, Tianyi Yang, Alvin Ya, Luke J. Tallon, Lisa Sadzewicz, Brent T. Harris, Jann Nagina Sarkaria, Fulai Jin · 2023 · Research Square
- Replisomes restrict SMC-mediated DNA-loop extrusion in vivoLiao, Qin, Brandão, Hugo B., Ren, Zhongqing, Wang, Xindan · 2025
- SMC complex unidirectionally translocates DNA by coupling segment capture with an asymmetric kleisin pathMasataka Yamauchi, Giovanni Bruno Brandani, Tsuyoshi Terakawa, Shoji Takada · 2025 · eLife
- AT-hook-dependent DNA loop extrusion by STAG1 drives 3D genome foldingRyota Sakata, Daniel Giménez-Llorente, Ana Losada, Tomoko Nishiyama · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Classical enhancers couple cis -regulatory logic with transcriptional condensates and 3D genome architectureVille Tiusanen, Divyesh Patel, Jihan Xia, Chi Xu, Subhamoy Datta, Ji Weon Yun, Samuele Cancellieri, Liangru Fei, Mehmet Yilmaz, Esa Pitkänen et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Cryo-EM and single molecule visualization unravel the role of human condensin II activation by M18BP1 in driving DNA compactionAlessandro Borsellini, Sebastian Chamera, Valentina Cecatiello, Joanna Andrecka, Alessandro Vannini · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Transcription directs Holliday junction branch migrationTom Powell, George G. B. Brown, Rachal M. Allison, Jon Alexander Harper, Matthew J. Neale, William H. Gittens · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- A dual role for CTCF in developmentNoemí Alonso Saiz, Moreno Martinovic, Miguel Rubio, Pinak Samal, Stefan Giselbrecht, Luca Braccioli, Elzo de Wit · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Cohesin extrudes chromatin loop unidirectionally through two modes of mechanisms in human cellsPing Wang, Lingyun Meng, Linghan Jiang, Yang Li, Jiaxiang Huang, Tiancheng YU, Haoxi Chai, Minji Kim, Xia Wang, Yijun Ruan · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Demystifying Cancer Etiology via 3D Genome MappingYuliang Feng, Siim Pauklin · 2020 · Trends in Genetics
- Cohesin in space and time: architecture and oligomerization in vivoSiheng Xiang, Douglas E. Koshland · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- STAG2 loss-of-function affects short-range genomic contacts and modulates urothelial differentiation in bladder cancer cellsLaia Richart, Eleonora Lapi, Véra Pancaldi, Mirabai Cuenca, Enrique Carrillo de Santa Pau, Miguel Madrid-Mencía, Hélène Neyret‐Kahn, François Radvanyi, Juan Antonio Rodríguez, Yasmina Cuartero et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Editorial overview: Genome architecture and expressionKerstin Bystricky, Matthias Merkenschlager · 2020 · Current Opinion in Genetics & Development
- The assisting role of Polη in transcription facilitates formation of damage-induced cohesionPei‐Shang Wu, Donald P. Cameron, Jan Grosser, Laura Baranello, Lena Ström · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Effects of forced cohesin eviction and retention on X-inactivation and autosomesAndrea J. Kriz, David Colognori, Hongjae Sunwoo, Behnam Nabet, Jeannie T. Lee · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Polymer Folding Simulations from Hi-C DataYinxiu Zhan, Luca Giorgetti, Guido Tiana · 2021 · Methods in molecular biology
- Condensin compacts DNA in 15 nm steps and requires FACT for extrusion on chromatinDavid Rueda, Swathi Sudhakar, Gemma L. M. Fisher, Pilar Gutiérrez-Escribano, Jonay García-Luis, Erin Cutts, Christopher Cawood, Luís Aragón · 2021 · Research Square
- From compartments to gene loops: Functions of the 3D genome in the human brainPanos Roussos, Samir Rahman, Pengfei Dong, Pasha Apontes, Michael B. Fernando, Kayla G. Townsley, Kiran Girdhar, Jaroslav M. Bendl, Zhiping Shao, Ruth Misir et al. · 2021 · Research Square
- A theory of the dynamics of DNA loop initiation in condensin/cohesin complexesBhavin S. Khatri · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- The loader complex Scc2/4 forms co-condensates with DNA as loading sites for cohesinSarah Zernia, Dieter Kamp, Johannes Stigler · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Faculty Opinions recommendation of Loop extrusion as a mechanism for formation of DNA damage repair foci.Sophie E. Polo · 2021 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Bioinformatics analysis of multi-omics data elucidates the primary function of Oct4 in gene regulation and pluripotency maintenanceLe Xiong · 2022 · eDiss (Georg-August-Universität Göttingen)
- Chromatin reorganization, signaling responses and non-coding RNA regulators in homeostasis and senescenceNataša Josipović · 2022 · eDiss (Georg-August-Universität Göttingen)
- Chromatin, nuclear organization and genome stability in mammalsLora Boteva, Nick Gilbert · 2021 · Elsevier eBooks
- Condensin Compacts DNA in 15nm steps and Requires FACT for Extrusion on ChromatinSwathi Sudhakar, Gemma L. M. Fisher, Pilar Gutiérrez-Escribano, Jonay García-Luis, Christopher Cawood, Luís Aragón, David Rueda · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Formation of the clamped state by Scc2 and DNA overcomes the constraints imposed by zipping-up of the SMC coiled coils on cohesin’s ATPaseMenelaos Voulgaris, Kim Nasmyth, Madhusudhan Srinivasan · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Cohesin is involved in transcriptional repression of stage-specific genes in the human malaria parasiteCatarina Rosa, Parul Singh, Ameya Sinha, Peter Rainer Preiser, Peter C. Dedon, Sebastian Baumgarten, Artur Scherf, Jessica M. Bryant · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- An SNF2 helicase-like protein links mitotic transcription termination to sister chromatid resolutionCatarina Carmo, João Coelho, Rui D Silva, Alexandra Tavares, A. Boavida, Paola Gaetani, R. Martinho, Raquel A. Oliveira · 2022 · bioRxiv
- The landscape of the repeated sequences in the human genomeFumiaki Uchiumi · 2022 · Elsevier eBooks