Genomics expands the mammalverse
Open accessAbstract
Diverse mammal genomes open a new portal to hidden aspects of evolutionary history
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The problem of non-independence is complicated even further by how unrepresentative most genomic datasets are of natural communities, owing to biases in which species have been sequenced more frequently.
“The problem of non-independence is complicated even further by how unrepresentative most genomic datasets are of natural communities, owing to biases in which species have been sequenced more frequently (Fig. 2)27–29.”
From A phylogenetic approach to comparative genomics (2025) · cites this paper as [29]
In “Genomics expands the mammalverse” (page not provided), the paper reports that available mammal genomes disproportionately represent large-bodied and high-latitude species, and warns that sampling biases can limit the generalizability of evolutionary inferences. It does not establish that most genomic datasets are unrepresentative of natural communities or explain how this compounds non-independence. (LLM, conf=0.84)
Experimental — accuracy not yet measuredGenomic databases are biased towards taxonomic groups that have been sequenced more frequently.
“This problem is made worse because genomic databases are biased towards taxonomic groups that have been sequenced more frequently27–29 (Fig. 2).”
From A phylogenetic approach to comparative genomics (2025) · cites this paper as [29]
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Cites
Progressive Cactus is a multiple-genome aligner for the thousand-genome era
Armstrong, J., Hickey, G., Diekhans, M., Fiddes, I. T., Novak, A. M., Deran, A., Fang, Q., Xie, D., Feng, S., Stiller, J., et al. (2020) · Nature · doi:10.1038/s41586-020-2871-y · Cited by 586 · see citing works
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Research works printed but not linked: 8
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A phylogenetic approach to comparative genomics
Dewar, A. E., Belcher, L. J., & West, S. A. (2025) · Nature Reviews Genetics · doi:10.1038/s41576-024-00803-0 · Cited by 41 · see citing works
- Authors
- Upham, N. S., & Landis, M. J.
- Affiliations
- Arizona State University (US)
- Washington University in St. Louis (US)
- Venue
- Science
- Published
- 2023-04-28
- Volume
- 380
- Issue
- 6643
- Pages
- 358-359
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- PMC
- PMC10876211
- OpenAlex
- W4367173739
- Cited by
- 11
- References
- 1
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 3 · 2023: 2
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Science Foundation (2040347)
- National Institutes of Health (1r21ai164268-01)
- National Institute of Allergy and Infectious Diseases (R21 AI164268)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
- Physical Sciences › Earth and Planetary Sciences › Paleontology › Evolution and Paleontology Studies
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Chromosomal and Genetic Variations
- Keywords
- mammalian evolution, comparative genomics, genome sequencing, evolutionary history
- MeSH terms
- Animals, Biological Evolution, Mammals, Phylogeny, Genetic Variation, Genome, Evolution, Molecular, Genomics
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