AI and the transformation of social science research
Abstract
Careful bias management and data fidelity are key
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Researchers have noted GPT's ability to help with computational social science tasks, detect misinformation, infer politicians' ideologies, write persuasive political arguments, respond to patient questions, simulate human research participants, and model collective behavior.
“Researchers have also recently noted GPT’s ability to help with computational social science tasks (49–54), detect misinformation (55), infer politicians’ ideologies (56), write persuasive political arguments (57), respond to patient questions (58), simulate human research participants (59–61), and model collective behavior (56).”
From GPT is an effective tool for multilingual psychological text analysis (2024) · cites this paper as [53]
LLMs may be unwilling to impersonate biased groups because they have been fine-tuned according to the normative preferences of highly educated liberals, who may have more concern about protecting marginalized groups than others.
“Researchers who want to use LLMs to impersonate biased groups, for example, may discover these tools are unwilling to perform such roles because they have been fine-tuned according to the normative preferences of highly educated liberals who may have more concern about the protection of marginalized groups than others (12, 64).”
From Can Generative AI improve social science? (2024) · cites this paper as [12]
Guard-rails in Generative AI probably improve safety for public use but may impede social scientists' ability to leverage bias for research purposes.
“Though such guard-rails probably improve the safety of Generative AI tools for public use, they may impede the ability of social scientists to leverage bias for research purposes (12).”
From Can Generative AI improve social science? (2024) · cites this paper as [12]
Generative AI may help increase external validity but may come at the cost of internal validity-the capacity of different groups to reproduce or replicate each other's results.
“Though Generative AI may help researchers increase the external validity of their research designs, this may come at the cost of internal validity—or the capacity of different groups of researchers to reproduce or replicate each other’s results (2, 12).”
From Can Generative AI improve social science? (2024) · cites this paper as [12]
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GPT is an effective tool for multilingual psychological text analysis
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GPT is an effective tool for multilingual psychological text analysisPreprint
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“181,182), LLMs are uniquely positioned to address these logistical issues and support CI research.”
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“Prior work has speculated that LLMs’ vast training data enable it to perform such representation 8 .”
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BackgroundHow should the advancement of large language models affect the practice of science?
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How developments in natural language processing help us in understanding human behaviour
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BackgroundWhy scientists trust AI too much — and what to do about it
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The use of synthetic data in tourism
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Humans create more novelty than ChatGPT when asked to retell a story
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“On the other hand, AI is increasingly employed in social science research to simulate social actors, analyze behavioral patterns, and address complex issues by leveraging its cognitive, reasoning, and linguistic capabilities.”
Toward LLM-agent-based modeling of transportation systems: A conceptual framework
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BackgroundMoral stereotyping in large language models
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Large Language Models and the Wisdom of Small Crowds
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A comprehensive review of artificial intelligence for pharmacology research
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Emergence of cooperation in the one-shot Prisoner’s dilemma through Discriminatory and Samaritan AIs
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Six Fallacies in Substituting Large Language Models for Human Participants
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Large language models can predict the results of social science experiments
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“Beyond these applications, LLM predictions could support power analyses, serve as Bayesian priors or approximate results where human experiments are ethically constrained (for example, misinformation research) 2 .”
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“Cultural diversity and bias [79]: AI can be influenced by biases inherent in the data and algorithms used to train systems.”
The Mixed Subjects Design: Treating Large Language Models as Potentially Informative Observations
Broska, D., Howes, M., & van Loon, A. (2025) · Sociological Methods & Research · doi:10.1177/00491241251326865 · Cited by 18 · see citing works
The power of bridging decision scales: Model coupling for advanced climate policy analysis
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Public administration with , of , and through AI: toward a new paradigm in the era of intelligence
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Potential benefits of employing large language models in research in moral education and development
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“Interestingly, recent developments in LLMs demonstrate significant emerging features simulating human psychological processes, which were unavailable in the previous simulation models (Grossmann et al., 2023).”
BackgroundArtificial intelligence chatbots mimic human collective behaviour
He, J. K., Wallis, F. P. S., Gvirtz, A., & Rathje, S. (2024) · British Journal of Psychology · doi:10.1111/bjop.12764 · Cited by 34 · see citing works
“Recent advances in AI chatbots have led some researchers to propose using them as agents to improve ABM's ability to simulate complex human collective dynamics (Epstein et al., 2023; Grossmann et al., 2023; Park et al., 2023; Pastor-Galindo et al., 2023).”
Theorizing with Large Language Models
Tranchero, M., Brenninkmeijer, C.-F., Murugan, A., & Nagaraj, A. (2024) · National Bureau of Economic Research · doi:10.3386/w33033 · Cited by 17 · see citing works
Wang, X., & Xie, F. (2025) · Journal of Knowledge Management · doi:10.1108/jkm-01-2025-0006 · Cited by 21 · see citing works
Using deep learning to generate key variables in global mitigation scenarios
Li, P., Zhu, R., McJeon, H. C., Byers, E. A., Zhou, P., & Ou, Y. (2025) · Nature Climate Change · doi:10.1038/s41558-025-02352-8 · Cited by 15 · see citing works
AI Surrogates and illusions of generalizability in cognitive science
Crockett, M. J., & Messeri, L. R. (2025) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2025.09.012 · Cited by 15 · see citing works
Counterfeit judgments in large language models
Perc, M. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2528527122 · Cited by 14 · see citing works
A large-scale comparison of divergent creativity in humans and large language models
Wang, D., Huang, D., Shen, H., & Uzzi, B. (2025) · Nature Human Behaviour · doi:10.1038/s41562-025-02331-1 · Cited by 14 · see citing works
Rudd, M. A., Bratcher, L., Collins, S., Branscum, D., Carson, M., Connell, S., David, E., Gronowska, M., Hess, S., Mitchell, A., et al. (2023) · Challenges · doi:10.3390/challe14040047 · Cited by 14 · see citing works
AI Thinking: a framework for rethinking artificial intelligence in practice
Newman-Griffis, D. R. (2025) · Royal Society Open Science · doi:10.1098/rsos.241482 · Cited by 18 · see citing works
Examining the Expanding Role of Synthetic Data Throughout the AI Development Pipeline
Kapania, S., Ballard, S. A., Kessler, A., & Vaughan, J. W. (2025) · ACM Conference on Fairness, Accountability, and Transparency (FAccT) · doi:10.1145/3715275.3732005 · Cited by 15 · see citing works
Uses, opportunities and risks of artificial intelligence in participatory urban planning
Raymond, C. M., Nummi, P., von Wirth, T., Poom, A., Ahdekivi, A., Barthel, S., Delmelle, E., Dunkel, E., Fagerholm, N., Grêt-Regamey, A., et al. (2025) · Discover Cities · doi:10.1007/s44327-025-00137-4 · Cited by 15 · see citing works
“The large language learning models associated with Generative AI could be used to emulate, interpret and test public comments without using traditional social survey methods [46].”
Psychologically-Valid Generative Agents: A Novel Approach to Agent-Based Modeling in Social Sciences
Mitsopoulos, K., Bose, R., Mather, B., Bhatia, A., Gluck, K., Dorr, B., Lebiere, C., & Pirolli, P. (2024) · AAAI Fall Symposia · doi:10.1609/aaaiss.v2i1.27698 · Cited by 18 · see citing works
Intersectional race–gender stereotypes in natural language
Bao, H., & GRIES, P. H. (2024) · British Journal of Social Psychology · doi:10.1111/bjso.12748 · Cited by 13 · see citing works
A step-by-step method for cultural annotation by LLMs
Dubourg, E., Thouzeau, V., & Baumard, N. (2024) · Frontiers in Artificial Intelligence · doi:10.3389/frai.2024.1365508 · Cited by 15 · see citing works
“These LLMs, like Generative Pre-trained Transformers (GPT), appear for the first time to be capable of annotating and parsing cultural data on a vast scale, and at an abstract level, by leveraging the contextual understanding inherent in these models (Brown et al., 2020; Grossmann et al., 2023).”
MethodChatGPT usage in the Reactome curation processPreprint
Tiwari, K. K., Matthews, L. R., May, B., Shamovsky, V., Orlic-Milacic, M., Rothfels, K., Ragueneau, E., Gong, C., Stephan, R., Li, N. T., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.11.08.566195 · Cited by 13 · see citing works
“5 to fields like social sciences [6], education [7], art [8], software [9], health care [10], clinical research [11], and medicine [12] provides a compelling motive to develop good benchmarking exercises to test the capabilities of current LLMs to streamline biological data curation and to track…”
BackgroundCapturing a moving target: Developing research on and with AI for Human Relations
Stollberger, J., Anand, S., & Dick, P. (2025) · Human Relations · doi:10.1177/00187267251332075 · Cited by 13 · see citing works
Stavropoulos, A., Crone, D. L., & Grossmann, I. (2024) · Behavior Research Methods · doi:10.3758/s13428-024-02441-0 · Cited by 12 · see citing works
“…often hidden in the “black box” of their complex architecture, and reliable tools have yet to be developed to interpret this (Demszky et al., 2023; Grossmann et al., 2023) Finally, the protection of data privacy is complicated by the fact that LLMs may store sensitive data on external servers and…”
InfluentialSelf-citationThe Fill-Mask Association Test (FMAT): Measuring propositions in natural language.
Bao, H. (2024) · Journal of Personality and Social Psychology · doi:10.1037/pspa0000396 · Cited by 13 · see citing works
Li, F., Su, H., Lee, C., Feng, S., Jiang, Z., & Sun, Z. (2025) · International Journal of Human-Computer Interaction · doi:10.1080/10447318.2024.2446511 · Cited by 15 · see citing works
“Specifically, large multi-modal models (LMMs) have demonstrated significant potential and broad application prospects in various fields such as industrial design and customer service [4], [5].”
Alonso, S. L. N., Ozili, P. K., Sastre-Hernández, B. M., Pacheco, L., & Central Bank of Nigeria, A. (2025) · Quantitative Finance and Economics · doi:10.3934/qfe.2025008 · Cited by 12 · see citing works
Alexiou, V. G., Sumpio, B. E., Vassiliou, A., Kakkos, S. K., & Geroulakos, G. (2024) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2024.11.014 · Cited by 11 · see citing works
Artificial Intelligence-Assisted Case Management in Social Work Services: A Systematic Review
Li, L., Wang, M., & Jian, M. (2025) · Research on Social Work Practice · doi:10.1177/10497315251329531 · Cited by 11 · see citing works
“…work professionals and AI experts to explore potential applications in social work practice (Goldkind, 2021), including developing LLMs capable of understanding and simulating human behavior (Grossmann et al., 2023), and utilizing ML to optimize social services and volunteer management (Yin, 2021).”
Large language models in climate and sustainability policy: limits and opportunities
Larosa, F., Hoyas, S., Conejero, J. A., García‐Martínez, J., Nerini, F. F., & Vinuesa, R. (2025) · Environmental Research Letters · doi:10.1088/1748-9326/addd36 · Cited by 11 · see citing works
Algorithmic CooperationPreprint
Kasberger, B., Martin, S., Normann, H., & Werner, T. (2023) · SSRN Electronic Journal · doi:10.2139/ssrn.4389647 · Cited by 11 · see citing works
Bodell, M. H., Magnusson, M., & Keuschnigg, M. (2024) · Sociological Methods & Research · doi:10.1177/00491241241268453 · Cited by 10 · see citing works
“If researchers fi nd ways to gain more control over labeling, replicability, and transparency (Grossmann et al., 2023), this transformative brand of text modeling will be in a good position to develop important alternatives to the seeded topic model.”
AI and Data Science for Public Policy
Benoit, K. R. (2024) · LSE Public Policy Review · doi:10.31389/lseppr.115 · Cited by 10 · see citing works
Generative Agents in Agent-Based Modeling: Overview, Validation, and Emerging Challenges
Adornetto, C., Mora, A., Hu, K., Garcia, L. I., Atchade-Adelomou, P., Greco, G., Alonso, L., & Larson, K. (2025) · IEEE Transactions on Artificial Intelligence · doi:10.1109/tai.2025.3566362 · Cited by 10 · see citing works
“…of large language models (LLMs) suggests we rethink the entire agent-based model (ABM) processes, from the design of new enhanced agents able to perceive, think, memorize, and act as likely as possible to humans [1], [2], to the methodologies and approaches by which we validate their behaviors.”
Leça, M. D. M., Valença, L., Santos, R., & Santos, R. D. S. (2025) · IEEE/ACM International Workshop on Methodological Issues with Empirical Studies in Software Engineering (WSESE) · doi:10.1109/wsese66602.2025.00013 · Cited by 14 · see citing works
“LLMs are now being used widely across research fields due to their potential to streamline text-heavy tasks [24], [27].”
- Authors
- Grossmann, I., Feinberg, M., Parker, D. C., Christakis, N. A., Tetlock, P. E., & Cunningham, W. A.
- Affiliations
- University of Waterloo (CA)
- University of Toronto (CA)
- Yale University (US)
- University of Pennsylvania (US)
- ORCID
- Venue
- Science
- Published
- 2023-06-16
- Volume
- 380
- Issue
- 6650
- Pages
- 1108-1109
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W4380763235
- Cited by
- 377
- References
- 10
- Citations by year
- 2026: 110 · 2025: 156 · 2024: 92 · 2023: 19
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Safety Research › Ethics and Social Impacts of AI
- Social Sciences › General Social Sciences › Computational and Text Analysis Methods
- Physical Sciences › Computer Science › Artificial Intelligence › Artificial Intelligence Applications
- Keywords
- artificial intelligence, social science research, research transformation, algorithmic bias, data fidelity, artificial intelligence in research
- MeSH terms
- Artificial Intelligence, Humans, Social Sciences, Bias
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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