CD8 T cells contribute to vaccine protection against SARS-CoV-2 in macaques
Liu, Jinyan, Yu, Jingyou, McMahan, Katherine, Jacob-Dolan, Catherine, He, Xuan, Giffin, Victoria, Wu, Cindy, Sciacca, Michaela +17 more·2022·Science Immunology
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- Multi-compartmental diversification of neutralizing antibody lineages dissected in SARS-CoV-2 spike-immunized macaquesMandolesi, Marco, Das, Hrishikesh, de Vries, Liset, Yang, Yiqiu, Kim, Changil, Dhinakaran, Manojj, Dopico, Xaquin Castro, Fischbach, Julian, Kim, Sungyong, Guryleva, Mariia et al. · 2024
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- Conserved CD8 T cell vaccines without B cell epitopes drive robust protection against SARS-CoV-2 that is enhanced by intranasal boostGenghao Chen, Thao Nguyen, Lindsay G. A. McKay, Sravya Sowdamini Nakka, Pan Hu, Julia McBride, Anthony C. T. Liang, Rachel M. Olson, James J. Moon, Andrew David Luster et al. · 2025 · Science Advances
- Recombinant Bacillus subtilis spores expressing SARS-CoV-2 spike protein induced humoral, mucosal, and cellular immunity in miceAtiqah Hazan, Amalia A. Saperi, Nurfatihah Zulkifli, NorAziyah MatRahim, Vunjia Tiong, Hai-Yen Lee, Sazaly AbuBakar · 2025 · Scientific Reports
- mRNA vaccine-induced IgG mediates nasal SARS-CoV-2 clearance in miceCharlie Fricke, Lorenz Ulrich, Jana Kochmann, Janina Gergen, Kristina Kovacikova, Nicole Roth, Julius Beer, Daniel Schnepf, Thomas C. Mettenleiter, Susanne Rauch et al. · 2024 · Molecular Therapy — Nucleic Acids
- A systems immunology study comparing innate and adaptive immune responses in adults to COVID-19 mRNA (BNT162b2/mRNA-1273) and adenovirus vectored vaccines (ChAdOx1-S) after the first, second and third dosesFeargal J. Ryan, Todd S. Norton, Conor McCafferty, Stephen J. Blake, Natalie E. Stevens, Jane James, Georgina L. Eden, Yee C. Tee, Saoirse C. Benson, Makutiro Ghislain Masavuli et al. · 2022 · medRxiv
- Intestinal helminth infection impairs vaccine-induced T cell responses and protection against SARS-CoV-2Pritesh Desai, Courtney E. Karl, Baoling Ying, Chieh-Yu Liang, Tamara García‐Salum, Ana Carolina Santana, Felipe ten-Caten, Joseph F. Urban, Sayda M. Elbashir, Darin K. Edwards et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Data from Impaired SARS-CoV-2 Variant Neutralization and CD8+ T-cell Responses Following 3 Doses of mRNA Vaccines in Myeloma: Correlation with Breakthrough InfectionsMaryam I. Azeem, Ajay K. Nooka, Uma Shanmugasundaram, Narayanaiah Cheedarla, Sayalee V. Potdar, Renee Julia Manalo, Alberto Moreno, Jeffrey M. Switchenko, Suneethamma Cheedarla, Deon Bryant Doxie et al. · 2023
- Cytokine profile of anti-spike CD4+T cells predicts humoral and CD8+T cell responses after anti-SARS-CoV-2 mRNA vaccinationÉric Tartour, Nadine Benhamouda, Anissa Besbes, Rebecca Bauer, Nesrine Mabrouk, Gauthier Gadouas, Corinne Desaint, Lucie Chevrier, Maeva Lefebvre, Anne Radenne et al. · 2023 · Research Square
- Antibody-mediated depletion of select T cell subsets in blood and tissue of nonhuman primatesMatthew S. Sutton, Allison N. Bucşan, Chelsea C. Lehman, Megha Kamath, Supriya Pokkali, Diogo M. Magnani, Robert A. Seder, Patricia A. Darrah, Mario Roederer · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
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- Development of a new vaccine at the laboratory scaleVijay Singh Bohara, Nilave Ranjan Bora, Surajbhan Sevda, Sachin Kumar · 2024 · Elsevier eBooks
- Reassuring humoral and cellular immune responses to SARS-CoV-2 vaccination in participants with systemic sclerosisJenna M. Benoit, Jessica A. Breznik, Angela Huynh, Braeden Cowbrough, Barbara Baker, Lauren Heessels, Sumiya Lodhi, Elizabeth Yan, Hina Bhakta, Rumi Clare et al. · 2024 · Immunology Letters
- Enhancing Immune Responses Through Modulation of Innate Cell Microenvironments in Lymph Nodes with Virus‐Mimetic VaccinesRunping Su, Tingting Yao, Chong Cao, Yaqi Yang, Mingshan Chen, Jianxiao Wu, Yue Zhao, Xiaoxiao Liu, Sha Li, Junqiang Ding et al. · 2025 · Angewandte Chemie
- Personalized Immune Profiling in Pediatric Transplant Recipients: Linking Atypical B Cells to Vaccine ResponseJohannes Wedel, Ying Tang, Bayan Alsairafi, Vicki Do, Madeline Maslyar, Ryan Fleming, Marc A. Schwartz, Ulrike Gerdemann, Alexandre Albanese, Vanessa Mitsialis et al. · 2025 · medRxiv
- Comparative single-cell immune responses in peripheral blood and lymph node of immunized SARS-CoV-2 challenged infant rhesus macaquesS. Anronikov, Cameron Meikle, Emma C. Milligan, Han Chen, Nilanjan Mukherjee, Zach Bjornson, B. Gaudilliere, Si-Zun Jiang, S. Permar, K. V. van Rompay et al. · 2025 · Frontiers in Immunology
- Effects of aging and inflammation on antigen-specific CD8+ T-cell responses that protect against severe disease following SARS-CoV-2 infectionTakuto Nogimori, Takuya Yamamoto · 2025 · Uirusu
- Ganoderma lucidum spore powder enhances IFN-α-mediated antiviral capacity of COVID-19 vaccine boosters revealed by single-cell multi-omics sequencingAnyao Li, Xiaoyan Lu, Rongfang Guo, Wenbo Guo, Penghui Yang, He Lou, Jie Chen, Enshan Huang, Ronghua Zhang, Hanbo Wang et al. · 2025 · Journal of Advanced Research
- Immunogenicity of COVID-19 Vaccines in the Upper Respiratory Tract: A Comparative Study of Pfizer-BioNTech and Johnson & Johnson Vaccines among Ugandan adultsVictoria Menya Biribawa, Musema Kizito, HenryRoger Ssemunywa, Priscillah Mulungi, Alex Mukisa, Judith Norah Namatovu, Claire Biribawa, Duncan Kabiito, Mudarshiru Bbuye, Henry Kyobe Bosa et al. · 2025
- Immunogenicity and protective efficacy of MERS CoV, NL140422, and HKU4 spike protein nanoparticle vaccinesPeter Halfmann, Jeong Soo Lee, Tong Wang, Augustine Duffy, Yoshihiro Kawaoka, Ravi S. Kane · 2026 · npj Viruses
- Structural Design of T-Cell Epitope-Based mRNA Vaccine Constructs Determines the Quality of T-Cell Immunity and Protective Efficacy Against SARS-CoV-2 in MiceVladimir A. Gushchin, Andrei E. Siniavin, Andrei A. Pochtovyi, Alina Sh. Dzharullaeva, Д. Н. Щербинин, Anastasiya S. Ungur, Тухватулин Амир Ильдарович, Inna V. Shuliakova, Denis A. Kleymenov, Elena P. Mazunina et al. · 2026 · Vaccines
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- Revisiting of the Role of CD8 + T‐Cells in Vaccine‐Induced Protection Against SARS‐CoV‐2 in Macaques via Mathematical ModelingMalik Muhammad Ibrahim, Jong Hyuk Byun, Malik Muhammad Naeem Mannan, Kwang Su Kim · 2026 · Complexity
- Induction of mucosal immune responses against SARS-CoV-2: a heterologous intramuscular mRNA-LNP prime/pulmonary recombinant subunit pull vaccination strategyMelike Ongun, Naga Suresh Kola, Dhruv Patel, Tasson C. Rodrigues, S. Schmidt, Abhijeet Girish Lokras, Henrik Franzyk, Søren R. Paludan, Thomas Rades, Aneesh Thakur et al. · 2026 · Scientific Reports
- Beyond the blood: Tissue-resident immunity shapes SARS-CoV-2 vaccine antibody responsesJuliane Schröter, Christiaan Hendrik van Dorp, Julia Davis‐Porada, John Ross Teijaro, Donna L. Färber, Andrew J. Yates · 2026 · bioRxiv (Cold Spring Harbor Laboratory)