Function of an Implanted Tissue Glucose Sensor for More than 1 Year in Animals
Open accessAbstract
An implanted tissue glucose sensor can provide stable readings of glucose concentrations for more than a year.
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A subcutaneous sensor using differential oxygen detection with glucose oxidase and catalase achieved accurate glucose measurements for more than one year by correcting for oxygen reduction differences.
“Accurate glucose measurements were carried out for >1 year by taking into account the difference in oxygen reduction at an electrode producing a glucose-modulated current and a reference electrode producing an oxygen-dependent current.31”
From Biocompatible Materials for Continuous Glucose Monitoring Devices (2013) · cites this paper as [31]
Oxygen diffusion to the sensor decays exponentially after implantation because of changes in tissue permeability.
“Of note, the oxygen diffusion to the sensor decays exponentially after sensor implantation due to changes in tissue permeability.31”
From Biocompatible Materials for Continuous Glucose Monitoring Devices (2013) · cites this paper as [31]
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References 34 · Cited by 179
Research works printed but not linked: 2
- [3]Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Study Group Tamborlane WV Beck RW Bode BW Buckingham B Chase HP Clemons R Fiallo-Scharer R Fox LA Gilliam LK Hirsch IB Huang ES Kollman C Kowalski AJ Laffel L Lawrence JM Lee J Mauras N O'Grady M Ruedy KJ Tansey M Tsalikian E Weinzimer S Wilson DM Wolpert H Wysocki T Xing D N. Eng. J. Med 2008 359 1464 1476 18779236
- [14]Glanz S Primer in Biostatistics 1992 3rd ed. New York McGraw-Hill, Inc.
- Authors
- Gough, D. A., Kumosa, L. S., Routh, T. L., Lin, J. T., & Lucisano, J. Y.
- Affiliations
- University of California San Diego (US)
- GlySens (United States) (US)
- Corresponding author
- Gough, David A.
- ORCID
- Kumosa, Lucas S.
- Venue
- Science Translational Medicine
- Published
- 2010-07-28
- Volume
- 2
- Issue
- 42
- Pages
- 42ra53-42ra53
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- PMC
- PMC4528300
- OpenAlex
- W2155173857
- Cited by
- 179
- References
- 34
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 7 · 2023: 11 · 2022: 4 · 2021: 11 · 2020: 11 · 2019: 12 · 2018: 11 · 2017: 14 · 2016: 14 · 2015: 14 · 2014: 15 · 2013: 23 · 2012: 15
- FWCI
- 12.08
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Translational Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Lund University Publications (Lund University) (submittedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK064570, R44DK077254, R56DK064570, R01DK077101, DK77101, R43DK077254, DK77254, DK64570)
- Topics
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrochemical sensors and biosensors
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Physical Sciences › Chemical Engineering › Bioengineering › Analytical Chemistry and Sensors
- Keywords
- implantable glucose sensor, wireless telemetry, diabetes mellitus, enzyme electrodes, subcutaneous tissue, pigs
- MeSH terms
- Animals, Glucose, Swine, Biosensing Techniques, Prostheses and Implants
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