Tick Acquisition of Ehrlichia canis from Dogs Treated with Doxycycline Hyclate
Open accessAbstract
Doxycycline generally alleviates clinical monocytic ehrlichiosis, but its efficacy in the control of monocytotropic ehrlichial pathogens requires further investigation. In this study, Ehrlichia canis was detected in dogs treated with doxycycline for 14 days and in ticks fed on these dogs, suggesting that treated dogs can remain reservoirs for E. canis.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Some treated dogs might remain as reservoirs of vector-borne diseases.
“some treated dogs might remain as reservoirs of vector-borne diseases.”
From Current Distribution of Selected Vector-Borne Diseases in Dogs in Spain (2020) · cites this paper as [77]
Cites
Dumler, J. S., Barbet, A. F., Bekker, C. P. J., Dasch, G. A., Palmer, G. H., Ray, S. C., Rikihisa, Y., & Rurangirwa, F. R. (2001) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/00207713-51-6-2145 · Cited by 2,089 · see citing works
Self-citationWoody, B. J., & Hoskins, J. D. (1991) · Veterinary Clinics of North America Small Animal Practice · doi:10.1016/s0195-5616(91)50009-7 · Cited by 211 · see citing works
Amplification of Ehrlichial DNA from Dogs 34 Months after Infection with Ehrlichia canis
Harrus, S., Waner, T., Aizenberg, I., et al. (1998) · Journal of Clinical Microbiology · doi:10.1128/jcm.36.1.73-76.1998 · Cited by 194 · see citing works
Wen, B., Rikihisa, Y., Mott, J. M., et al. (1997) · Journal of Clinical Microbiology · doi:10.1128/jcm.35.7.1852-1855.1997 · Cited by 191 · see citing works
Self-citationRecent Advances in Determining the Pathogenesis of Canine Monocytic Ehrlichiosis
Harrus, S., Waner, T., Bark, H., et al. (1999) · Journal of Clinical Microbiology · doi:10.1128/jcm.37.9.2745-2749.1999 · Cited by 165 · see citing works
Infectious Diseases of the Dog and Cat, 3rd ed.
Weese, J. S. (2007) · Europe PMC (PubMed Central) · Cited by 142 · see citing works
Bremer, W. G., Schaefer, J. J., Wagner, E. R., Ewing, S. A., Rikihisa, Y., Needham, G. R., Jittapalapong, S., Moore, D. L., & Stich, R. W. (2005) · Veterinary Parasitology · doi:10.1016/j.vetpar.2005.04.030 · Cited by 122 · see citing works
Self-citationWaner, T., Harrus, S., Bark, H., BOGIN, E., Avidar, Y., & Keysary, A. (1997) · Veterinary Parasitology · doi:10.1016/s0304-4017(96)01130-2 · Cited by 117 · see citing works
Harrus, S., Kenny, M. J., Miara, L., et al. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.11.4488-4490.2004 · Cited by 101 · see citing works
Characterization of the subclinical phase of ehrlichiosis in dogs
Codner, E. C., & Farris-Smith, L. L. (1986) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.1986.189.01.47 · Cited by 100 · see citing works
Reisolation of Ehrlichia canis from blood and tissues of dogs after doxycycline treatment
Iqbal, Z. M., & Rikihisa, Y. (1994) · Journal of Clinical Microbiology · doi:10.1128/jcm.32.7.1644-1649.1994 · Cited by 96 · see citing works
Self-citationStich, R. W., Schaefer, J. J., Bremer, W. G., Needham, G. R., & Jittapalapong, S. (2008) · Veterinary Parasitology · doi:10.1016/j.vetpar.2008.09.013 · Cited by 93 · see citing works
Self-citationBreitschwerdt, E. B., Hegarty, B. C., & Hancock, S. I. (1998) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.42.2.362 · Cited by 88 · see citing works
The Brown Dog Tick Rhipicephalus sanguineus and the Dog as Experimental Hosts of Ehrlichia canis
Lewis, G. E., Ristic, M., Smith, R. D., Lincoln, T., & Stephenson, Ε. H. (1977) · American Journal of Veterinary Research · doi:10.2460/ajvr.1977.38.12.1953 · Cited by 88 · see citing works
Bartsch, R. C., & Greene, R. T. (1996) · Journal of Veterinary Internal Medicine · doi:10.1111/j.1939-1676.1996.tb02061.x · Cited by 80 · see citing works
Harrus, S., Waner, T., Aizenberg, I., et al. (1998) · Journal of Clinical Microbiology · doi:10.1128/jcm.36.7.2140-2142.1998 · Cited by 75 · see citing works
Survey of Ehrlichia canis antibodies among dogs in Israel
Baneth, G., Waner, T., Koplah, A., et al. (1996) · Veterinary Record · doi:10.1136/vr.138.11.257 · Cited by 50 · see citing works
Stich, R. W., Rikihisa, Y., Ewing, S. A., et al. (2002) · Journal of Clinical Microbiology · doi:10.1128/jcm.40.2.540-546.2002 · Cited by 48 · see citing works
Self-citationCanine ehrlichiosis in Egypt: sero-epidemiological survey.
Botros, B. A., Elmolla, M. S., Salib, A. W., et al. (1995) · PubMed · Cited by 38 · see citing works
Skotarczak, B. (2003) · PubMed · Cited by 32 · see citing works
Davidson, D. E., Dill, G. S., Tingpalapong, M., et al. (1978) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.1978.172.06.697 · Cited by 23 · see citing works
Ewing, S. A. (1969) · PubMed · Cited by 20 · see citing works
Self-citationOgunkoya, A., Adeyanju, J., & Abduhllahi, R. (1985) · Veterinary Quarterly · doi:10.1080/01652176.1985.9693974 · Cited by 5 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
The increasing recognition of rickettsial pathogens in dogs and people
Nicholson, W. L., Allen, K. E., McQuiston, J. H., Breitschwerdt, E. B., & Little, S. E. (2010) · Trends in Parasitology · doi:10.1016/j.pt.2010.01.007 · Cited by 251 · see citing works
Current Distribution of Selected Vector-Borne Diseases in Dogs in Spain
Montoya-Alonso, J. A., Morchón, R., Costa-Rodríguez, N., Matos, J. I., Falcón-Cordón, Y., & Carretón, E. (2020) · Frontiers in Veterinary Science · doi:10.3389/fvets.2020.564429 · Cited by 59 · see citing works
- Authors
- Schaefer, J. J., Needham, G. R., Bremer, W. G., Rikihisa, Y., Ewing, S. A., & Stich, R. W.
- Affiliations
- Departments of Veterinary Preventive Medicine
- Entomology
- The Ohio State University (US)
- Oklahoma State University (US)
- University of Missouri (US)
- Corresponding author
- Stich, R. W.
- Venue
- Antimicrobial Agents and Chemotherapy
- Publisher
- American Society for Microbiology
- Published
- 2007-09
- Volume
- 51
- Issue
- 9
- Pages
- 3394-3396
- ISSN
- 0066-4804 (ISSN-L)
- 1098-6596
- PMC
- PMC2043173
- OpenAlex
- W2098515394
- Cited by
- 30
- References
- 23
- Citations by year
- 2026: 1 · 2024: 3 · 2023: 1 · 2022: 1 · 2021: 3 · 2020: 2 · 2019: 1 · 2018: 1 · 2017: 2 · 2014: 1 · 2013: 3 · 2012: 1
- FWCI
- 2.53
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Antimicrobial Agents and Chemotherapy (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- SHAREOK (University of Oklahoma; Oklahoma State University; Central Oklahoma University) (acceptedVersion, other-oa)
- SHAREOK (University of Oklahoma; Oklahoma State University; Central Oklahoma University) (submittedVersion, other-oa)
- Funders
- National Institute of Allergy and Infectious Diseases (AI47932, R01AI047932)
- Topics
- Life Sciences › Immunology and Microbiology › Parasitology › Vector-borne infectious diseases
- Life Sciences › Immunology and Microbiology › Microbiology › Microbial infections and disease research
- Life Sciences › Agricultural and Biological Sciences › Insect Science › Insect symbiosis and bacterial influences
- Keywords
- Ehrlichia canis, doxycycline, dogs, ticks, tick-borne transmission, reservoir hosts, monocytic ehrlichiosis, canine ehrlichiosis, antimicrobial efficacy
- MeSH terms
- Animals, Anti-Bacterial Agents, Arachnid Vectors, Dog Diseases, Dogs, Doxycycline, Ehrlichiosis, Reverse Transcriptase Polymerase Chain Reaction, Ehrlichia canis, Rhipicephalus sanguineus
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review