Impact of Accelerate Pheno and BacT/Alert Virtuo on Clinical Processes and Outcomes in Patients with Sepsis and Concurrent Gram-Negative Bacteremia
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The Accelerate Pheno and BacT/Alert Virtuo systems may improve bacteremia management. Here, we evaluated the impact of both devices on outcomes in patients with sepsis and concurrent Gram-negative bacteremia.
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Improvements in TAT and faster treatment adaptation have been attributed to better outcomes in patients with BSI, including improved survival rates in some studies.
“While the exact cause of this finding cannot be determined due to the observational nature of the study, improvements in TAT and faster treatment adaptation have been attributed to better outcomes in patients with BSI, including improved survival rates in some studies [23–25].”
From Lab efficiency and improvements in the management of bloodstream infections: a before and after study (2025) · cites this paper as [23]
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Cited by
Sorted by citations
Paluch, M., Ettahar, N., Lagraulet, B., Cattoen, C., Rethore, E., Dubrulle, A., Abad, L., Canis, F., Wayenberg, L., Lambiotte, F., et al. (2025) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-025-05200-x · Cited by 5 · see citing works
“While the exact cause of this finding cannot be determined due to the obser - vational nature of the study, improvements in TAT and faster treatment adaptation have been attributed to better outcomes in patients with BSI, including improved survival rates in some studies [ 23 – 25].”
- Authors
- Babowicz, F., LaPlante, R., Mitchell, C., O’Donnell, J. N., Tobin, E., George, M., & Carreno, J. J.
- Affiliations
- Albany College of Pharmacy and Health Sciences (US)
- Albany Medical Center Hospital (US)
- Upstate Infectious Diseases Associates, Albany, New York, USA
- Corresponding author
- O’Donnell, J. Nicholas
- Carreno, Joseph J.
- Venue
- Antimicrobial Agents and Chemotherapy
- Publisher
- American Society for Microbiology
- Published
- 2021-05-18
- Volume
- 65
- Issue
- 6
- ISSN
- 0066-4804 (ISSN-L)
- 1098-6596
- PMC
- PMC8315910
- OpenAlex
- W3137903049
- Cited by
- 28
- References
- 0
- Citations by year
- 2026: 6 · 2025: 6 · 2024: 3 · 2023: 6 · 2022: 5 · 2021: 2
- FWCI
- 2.81
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Antimicrobial Agents and Chemotherapy (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Bacterial Identification and Susceptibility Testing
- Health Sciences › Medicine › Epidemiology › Sepsis Diagnosis and Treatment
- Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Antibiotic Use and Resistance
- Keywords
- sepsis, gram-negative bacteremia, rapid molecular diagnostics, sepsis severity score, antibiotic use, length of hospital stay, clinical outcomes
- MeSH terms
- Blood Culture, Adolescent, Humans, Prospective Studies, Retrospective Studies, Bacteremia, Sepsis, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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