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New polymeric biocides: synthesis and antibacterial activities of polycations with pendant biguanide groups
Open accessAbstract
Acrylate monomers with pendant biguanide groups were successfully synthesized, and their homopolymers and copolymers were prepared with acrylamide. These cationic disinfectants of polymeric forms exhibited high antibacterial activity against gram-positive bacteria, whereas they were less active against gram-negative bacteria. It was found that the activity of the polymeric disinfectants was much higher than that of the monomeric species, and the difference in activity between the polymers and the monomers was discussed on the basis of their contributions to each elementary process of the lethal action.
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Cited by
The Chemistry and Applications of Antimicrobial Polymers: A State-of-the-Art Review
Kenawy, E.-R., Worley, S. D., & Broughton, R. (2007) · Biomacromolecules · doi:10.1021/bm061150q · Cited by 1,558
Murata, H., Koepsel, R. R., Matyjaszewski, K., & Russell, A. J. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.06.012 · Cited by 722
Lim, S.-H., & Hudson, S. M. (2004) · Carbohydrate Research · doi:10.1016/j.carres.2003.10.024 · Cited by 710
Antimicrobial polymers: mechanism of action, factors of activity, and applications
Timofeeva, L., & Kleshcheva, N. (2011) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-010-2920-9 · Cited by 579
Jain, A., Duvvuri, L. S., Farah, S., Beyth, N., Domb, A. J., & Khan, W. (2014) · Advanced Healthcare Materials · doi:10.1002/adhm.201400418 · Cited by 485
Metadata
- Authors
- Ikeda, T., Yamaguchi, H., & Tazuke, S.
- Venue
- Antimicrobial Agents and Chemotherapy
- Publisher
- American Society for Microbiology
- Published
- 1984-08
- Volume
- 26
- Issue
- 2
- Pages
- 139-144
- ISSN
- 0066-4804 (ISSN-L)
- 1098-6596
- OpenAlex
- W1963694745
- Cited by
- 203
- References
- 0
- FWCI
- 2.22
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: New polymeric biocides: synthesis and antibacterial activities of polycations with pendant biguanide groups. https://app.cochat.ai/papers/10.1128/aac.26.2.139
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- Ikeda, T., Yamaguchi, H., & Tazuke, S. (1984). New polymeric biocides: synthesis and antibacterial activities of polycations with pendant biguanide groups. Antimicrobial Agents and Chemotherapy. https://doi.org/10.1128/aac.26.2.139
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
