The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Therapy of human hydatid disease with mebendazole and albendazole
Open accessAbstract
We report our experience in the treatment with benzoimidazole carbamates (mebendazole and albendazole) of 337 patients affected by hydatid cysts with different localizations. The treated cysts showed degenerative modifications in 50.6% of the cases after mebendazole treatment and in about 80% after albendazole treatment. Relapses after therapy were observed in 30% of the cases; about 95% of the recurring cysts showed good susceptibility to a further cycle of therapy with benzoimidazole carbamates. Side effects observed with either drug were not severe and always reversible, consisting mainly of abdominal pains and increased levels of transaminases in serum. Among the factors that may influence the therapeutic results are the drug employed, the age of the cysts, the age of the patient, and the localization of the cysts and their morphological characteristics. Moreover, it can be hypothesized that each hydatid cyst has an intrinsic sensitivity to benzoimidazole carbamates.
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Cites
Treatment of hepatic hydatid disease with mebedazole: preliminary results in four cases.
Bekhti, A., Schaaps, J. P., Capron, M., Dessaint, J. P., Santoro, F., & Capron, A. (1977) · BMJ · doi:10.1136/bmj.2.6094.1047 · Cited by 199
HEATH, D. (1974) · The Lancet · doi:10.1016/s0140-6736(74)91517-7 · Cited by 81
Verheyen, A. (1982) · Zeitschrift f�r Parasitenkunde Parasitology Research · doi:10.1007/bf00929514 · Cited by 27
Cited by
Albendazole in treatment of human cystic echinococcosis: 12 years of experience
Horton, R. J. (1997) · Acta Tropica · doi:10.1016/s0001-706x(96)00640-7 · Cited by 288
Echinococcus granulosus infection: clinical presentation, medical treatment and outcome
Kern, P. (2003) · Langenbeck's Archives of Surgery · doi:10.1007/s00423-003-0418-y · Cited by 133
Albendazole for the treatment of echinococcosis
John, H. (2003) · Fundamental & Clinical Pharmacology · doi:10.1046/j.1472-8206.2003.00171.x · Cited by 116
Effect of mebendazole on human cystic echinococcosis: the role of dosage and treatment duration
Vutova, K., Mechkov, G., Vachkov, P., Petkov, R., Georgiev, P., Handjiev, S., Ivanovh, A., & Todorov, T. (1999) · Annals of Tropical Medicine & Parasitology · doi:10.1080/00034983.1999.11813432 · Cited by 61
Dual treatment of albendazole in hepatic hydatidosis: New therapeutic modality in 52 cases
POLAT, C., DERVISOGLU, A., HOKELEK, M., YETIM, I., BUYUKKARABACAK, Y., OZKUTUK, Y., & ERZURUMLU, K. (2005) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2004.03535.x · Cited by 23
Metadata
- Authors
- Teggi, A., Lastilla, M. G., & De Rosa, F.
- Venue
- Antimicrobial Agents and Chemotherapy
- Publisher
- American Society for Microbiology
- Published
- 1993-08
- Volume
- 37
- Issue
- 8
- Pages
- 1679-1684
- ISSN
- 0066-4804 (ISSN-L)
- 1098-6596
- OpenAlex
- W2018597228
- Cited by
- 228
- References
- 3
- FWCI
- 2.16
- Type
- journal article
- Language
- en
- Open access
- green
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- Teggi, A., Lastilla, M. G., & De Rosa, F. (1993). Therapy of human hydatid disease with mebendazole and albendazole. Antimicrobial Agents and Chemotherapy. https://doi.org/10.1128/aac.37.8.1679
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