Serum therapy revisited: animal models of infection and development of passive antibody therapy
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Clinical benefit of passive immunization was demonstrated for invasive bacterial infections, various viral diseases, and anti-fungal therapy.
“Clinical benefit was demonstrated for invasive bacterial infections (Casadevall & Scharff, 1994), for various viral diseases (Janeway, 1945; Hammon et al, 1953), as well as for anti‐fungal therapy (Bugli et al, 2013)”
From mRNA mediates passive vaccination against infectious agents, toxins, and tumors (2017) · cites this paper as Casadevall & Scharff, 1994
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“Clinical benefit was demonstrated for invasive bacterial infections (Casadevall & Scharff, 1994), for various viral diseases (Janeway, 1945; Hammon et al, 1953), as well as for anti-fungal therapy (Bugli et al, 2013), and polyclonal antibody products were licensed for several viruses.”
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Self-citation
- Authors
- Casadevall, A., & Scharff, M. D.
- Affiliations
- Albert Einstein College of Medicine (US)
- Venue
- Antimicrobial Agents and Chemotherapy
- Publisher
- American Society for Microbiology
- Published
- 1994-08
- Volume
- 38
- Issue
- 8
- Pages
- 1695-1702
- ISSN
- 0066-4804 (ISSN-L)
- 1098-6596
- PMC
- PMC284624
- OpenAlex
- W2031152984
- Cited by
- 251
- References
- 84
- Citations by year
- 2025: 8 · 2024: 6 · 2023: 10 · 2022: 10 · 2021: 20 · 2020: 29 · 2019: 5 · 2018: 7 · 2017: 10 · 2016: 4 · 2015: 6 · 2014: 12 · 2013: 6 · 2012: 8
- FWCI
- 5.86
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Antimicrobial Agents and Chemotherapy (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Cancer Institute (CA-39839)
- National Institute of Allergy and Infectious Diseases (AI13342, AI33774, R01AI033774)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Monoclonal and Polyclonal Antibodies Research
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Historical Medical Research and Treatments
- Life Sciences › Immunology and Microbiology › Microbiology › Bacterial Infections and Vaccines
- Keywords
- serum therapy, animal models of infection, passive antibody therapy, passive immunization
- MeSH terms
- Animals, Disease Models, Animal, Humans, Immunization, Passive, Meningitis, Meningococcal, Pneumococcal Infections
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