The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori
Open accessAbstract
Twelve clarithromycin-resistant Helicobacter pylori isolates (100% of resistant isolates examined) from seven different patients each contained an A-->G transition mutation within a conserved loop of 23S rRNA. A-->G transition mutations at positions cognate with Escherichia coli 23S rRNA positions 2058 and 2059 were identified. Clarithromycin-susceptible H. pylori isolates from 14 different patients displayed no polymorphisms in a conserved loop within domain V of 23S rRNA. The study is the first to report mutations in H. pylori associated with resistance to an antimicrobial agent used in established peptic ulcer treatment regimens.
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Graham, D. Y., Lew, G. M., Klein, P. D., Evans, D. G., Evans, D. J., Saeed, Z. A., & Malaty, H. M. (1992) · Annals of Internal Medicine · doi:10.7326/0003-4819-116-9-705 · Cited by 909
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Mégraud, F. (2004) · Gut · doi:10.1136/gut.2003.022111 · Cited by 955
Helicobacter pylori infection and antibiotic resistance — from biology to clinical implications
Tshibangu-Kabamba, E., & Yamaoka, Y. (2021) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-021-00449-x · Cited by 517
Helicobacter pylori and antimicrobial resistance: molecular mechanisms and clinical implications
Gerrits, M. M., van Vliet, A. H., Kuipers, E. J., & Kusters, J. G. (2006) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(06)70627-2 · Cited by 329
Antibiotic resistance in : Implications for therapy
GRAHAM, D. (1998) · Gastroenterology · doi:10.1016/s0016-5085(98)70100-3 · Cited by 300
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Metadata
- Authors
- Versalovic, J., Shortridge, D., Kibler, K., Griffy, M. V., Beyer, J., Flamm, R. K., Tanaka, S. K., Graham, D. Y., & Go, M. F.
- Venue
- Antimicrobial Agents and Chemotherapy
- Publisher
- American Society for Microbiology
- Published
- 1996-02
- Volume
- 40
- Issue
- 2
- Pages
- 477-480
- ISSN
- 0066-4804 (ISSN-L)
- 1098-6596
- OpenAlex
- W1894963259
- Cited by
- 501
- References
- 1
- FWCI
- 32.09
- Type
- journal article
- Language
- en
- Open access
- green
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- Versalovic, J., Shortridge, D., Kibler, K., Griffy, M. V., Beyer, J., Flamm, R. K., Tanaka, S. K., Graham, D. Y., & Go, M. F. (1996). Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori. Antimicrobial Agents and Chemotherapy. https://doi.org/10.1128/aac.40.2.477
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
