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Selection of multiple-antibiotic-resistant (mar) mutants of Escherichia coli by using the disinfectant pine oil: roles of the mar and acrAB loci

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Moken, M C, McMurry, L M, Levy, S B·1997·Antimicrobial Agents and Chemotherapy
DOI 10.1128/aac.41.12.2770
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Abstract

Mutants of Escherichia coli selected for resistance to the disinfectant pine oil or to a household product containing pine oil also showed resistance to multiple antibiotics (tetracycline, ampicillin, chloramphenicol, and nalidixic acid) and overexpressed the marA gene. Likewise, antibiotic-selected Mar mutants, which also overexpress marA, were resistant to pine oil. Deletion of the mar or acrAB locus, the latter encoding a multidrug efflux pump positively regulated in part by MarA, increased the susceptibility of wild-type and mutant strains to pine oil.

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Metadata

Authors
Moken, M. C., McMurry, L. M., & Levy, S. B.
Venue
Antimicrobial Agents and Chemotherapy
Publisher
American Society for Microbiology
Published
1997-12
Volume
41
Issue
12
Pages
2770-2772
ISSN
  • 0066-4804 (ISSN-L)
  • 1098-6596
DOI
10.1128/aac.41.12.2770
OpenAlex
W1955800727
Cited by
203
References
0
FWCI
4.68
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Selection of multiple-antibiotic-resistant (mar) mutants of Escherichia coli by using the disinfectant pine oil: roles of the mar and acrAB loci. https://app.cochat.ai/papers/10.1128/aac.41.12.2770
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Moken, M. C., McMurry, L. M., & Levy, S. B. (1997). Selection of multiple-antibiotic-resistant (mar) mutants of Escherichia coli by using the disinfectant pine oil: roles of the mar and acrAB loci. Antimicrobial Agents and Chemotherapy. https://doi.org/10.1128/aac.41.12.2770

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.