Resistance Mechanisms in Clinical Isolates of Candida albicans

Molecular Cloning: A Laboratory Manual

Sambrook, J., Fritsch, E., & Maniatis, T. (1989) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 133,589

National Committee for Clinical Laboratory Standards

Bruck, E. (1980) · PEDIATRICS · doi:10.1542/peds.65.1.187 · Cited by 14,736

A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformaion of Escherichia coli

Hoffman, C. S., & Winston, F. (1987) · Gene · doi:10.1016/0378-1119(87)90131-4 · Cited by 2,492

Clinical, Cellular, and Molecular Factors That Contribute to Antifungal Drug Resistance

White, T. C., Marr, K. A., & Bowden, R. A. (1998) · Clinical Microbiology Reviews · doi:10.1128/cmr.11.2.382 · Cited by 1,353

Development of Interpretive Breakpoints for Antifungal Susceptibility Testing: Conceptual Framework and Analysis of In Vitro-In Vivo Correlation Data for Fluconazole, Itraconazole, and Candida Infections

Rex, J. H., Pfaller, M. A., Galgiani, J. N., Bartlett, M. S., Espinel-Ingroff, A., Ghannoum, M. A., Lancaster, M., Odds, F. C., Rinaldi, M. G., Walsh, T. J., et al. (1997) · Clinical Infectious Diseases · doi:10.1093/clinids/24.2.235 · Cited by 855

Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters

Sanglard, D., Kuchler, K., Ischer, F., Pagani, J. L., Monod, M., & Bille, J. (1995) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.39.11.2378 · Cited by 815

Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus

White, T. C. (1997) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.41.7.1482 · Cited by 612

Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene

Sanglard, D., Ischer, F., Monod, M., & Bille, J. (1997) · Microbiology · doi:10.1099/00221287-143-2-405 · Cited by 587

Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungals

Prasad, R., De Wergifosse, P., Goffeau, A., & Balzi, E. (1995) · Current Genetics · doi:10.1007/bf00352101 · Cited by 486

Prevalence of Molecular Mechanisms of Resistance to Azole Antifungal Agents in Candida albicans Strains Displaying High-Level Fluconazole Resistance Isolated from Human Immunodeficiency Virus-Infected Patients

Perea, S., López-Ribot, J. L., Kirkpatrick, W. R., McAtee, R. K., Santillán, R. A., Martı́nez, M., Calabrese, D., Sanglard, D., & Patterson, T. F. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.10.2676-2684.2001 · Cited by 470

Multidrug-Resistant Transporter Mdr1p-Mediated Uptake of a Novel Antifungal Compound

Sun, N., Li, D., Fonzi, W. A., Li, X. V., Zhang, L., & Calderone, R. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01504-13 · Cited by 30

β-lactam substituted polycyclic fused pyrrolidine/pyrrolizidine derivatives eradicate C. albicans in an ex vivo human dentinal tubule model by inhibiting sterol 14-α demethylase and cAMP pathway

Meiyazhagan, G., Beaula, W. S., Biswal, J., Prabhu, D., Raghavan, S., prasad, S. R., Pitani, R., Kandaswamy, D., Raghunathan, R., Jeyakanthan, J., et al. (2015) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2015.12.020 · Cited by 30

Coumarin Antifungal Lead Compounds from Millettia thonningii and Their Predicted Mechanism of Action

Ayine‐Tora, D. M., Kingsford-Adaboh, R., Asomaning, W. A., Harrison, J. D., Mills-Robertson, F. C., Bukari, Y., Sakyi, P. O., Kaminta, S., & Reynisson, J. (2016) · Molecules · doi:10.3390/molecules21101369 · Cited by 30

In Vitro Susceptibility of a Large Collection of Candida Strains Against Fluconazole and Voriconazole by Using the CLSI Disk Diffusion Assay

Azevedo, A. C., Bizerra, F. C., da Matta, D. A., de Almeida, L. P., Rosas, R., & Colombo, A. L. (2010) · Mycopathologia · doi:10.1007/s11046-010-9387-1 · Cited by 30

Population dynamics and the evolution of antifungal drug resistance in Candida albicans

Huang, M., & Kao, K. C. (2012) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2012.02587.x · Cited by 30

Antifungal susceptibility and genotypes of Candida albicans strains from patients with vulvovaginal candidiasis

Liu, X. P., Fan, S., Bai, F., Li, J., & Liao, Q. P. (2008) · Mycoses · doi:10.1111/j.1439-0507.2008.01539.x · Cited by 30

cDNA microarray analysis of differential gene expression and regulation in clinically drug-resistant isolates of Candida albicans from bone marrow transplanted patients

Xu, Z. Q., Zhang, L., Zhang, J., Cao, Y., Yu, Y.-Y., Wang, D., Ying, K., Chen, W., & Jiang, Y. (2006) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2006.03.004 · Cited by 30

Loss of Upc2p-Inducible ERG3 Transcription Is Sufficient To Confer Niche-Specific Azole Resistance without Compromising Candida albicans Pathogenicity

Luna-Tapia, A., Willems, H. M. E., Parker, J. E., Tournu, H., Barker, K. S., Nishimoto, A. T., Rogers, P. D., Kelly, S. L., Peters, B. M., & Palmer, G. E. (2018) · mBio · doi:10.1128/mbio.00225-18 · Cited by 29

Oxidative and nitrosative stress responses during macrophage–Candida albicansbiofilm interaction

Miranda, J. E. A., Baronetti, J. L., Sotomayor, C. E., & Paraje, M. G. (2017) · Medical Mycology · doi:10.1093/mmy/myx143 · Cited by 30

Fluconazole inhibits cellular ergosterol synthesis to confer synergism with berberine against yeast cells

Yang, Z., Wang, Q., Ma, K., Shi, P., Liu, W., & Huang, Z. (2017) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2017.12.011 · Cited by 29

The Antibiofilm Role of Biotics Family in Vaginal Fungal Infections

Boahen, A., Than, L. T. L., Loke, Y.-L., & Chew, S. Y. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.787119 · Cited by 34

Emergence of Azoles Resistance Candida species in Iranian AIDS defined patients with oropharyngeal candidiasis

Katiraee, F., Teifoori, F., & Soltani, M. (2015) · Current Medical Mycology · doi:10.18869/acadpub.cmm.1.3.11 · Cited by 29

Trafficking through the Late Endosome Significantly Impacts Candida albicans Tolerance of the Azole Antifungals

Luna-Tapia, A., Kerns, M. E., Eberle, K. E., Jursic, B. S., & Palmer, G. E. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.04239-14 · Cited by 28

Research of Mrr1, Cap1 and MDR1 in Candida albicans resistant to azole medications

Feng, W., Yang, J., Yang, L., Li, Q., Zhu, X., Xi, Z., Qiao, Z., & Wen, C. (2017) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2017.5518 · Cited by 27

Amino Acid-Derived 1,2-Benzisothiazolinone Derivatives as Novel Small-Molecule Antifungal Inhibitors: Identification of Potential Genetic Targets

Alex, D., Gay‐Andrieu, F., May, J. P., Thampi, L. M., Dou, D., Mooney, A., Groutas, W. C., & Calderone, R. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00477-12 · Cited by 28

Usnic Acid Activity on Oxidative and Nitrosative Stress of Azole-Resistant Candida albicans Biofilm

Peralta, M. A., Silva, M. D. C. C., Ortega, M. G., Cabrera, J. L., & Paraje, M. G. (2016) · Planta Medica · doi:10.1055/s-0042-116442 · Cited by 27

The antioxidant activity of a prenyl flavonoid alters its antifungal toxicity on Candida albicans biofilms

Peralta, M. A., Ortega, M. G., Cabrera, J. L., & Paraje, M. G. (2018) · Food and Chemical Toxicology · doi:10.1016/j.fct.2018.02.042 · Cited by 27

Molecular mechanism of azoles resistant Candida albicans in a patient with chronic mucocutaneous candidiasis

Zhang, M.-R., Zhao, F., Wang, S., Lv, S., Mou, Y., Yao, C.-L., Zhou, Y., & Li, F.-Q. (2020) · BMC Infectious Diseases · doi:10.1186/s12879-020-4856-8 · Cited by 26

Candida parapsilosis Sensu Stricto Antifungal Resistance Mechanisms and Associated Epidemiology

Franconi, I., Rizzato, C., Poma, N. V., Tavanti, A., & Lupetti, A. (2023) · Journal of Fungi · doi:10.3390/jof9080798 · Cited by 27

Shuttle vectors for Candida albicans: control of plasmid copy number and elevated expression of cloned genes

Du, W., Coaker, M., Sobel, J. D., & Akins, R. A. (2004) · Current Genetics · doi:10.1007/s00294-004-0499-3 · Cited by 26

Mitracarpus frigidus: A promising antifungal in the treatment of vulvovaginal candidiasis

Campos, L. M., de Melo, L., Lemos, A. S. D. O., Guedes, M. C. M. R., Silva, T. P. D., de Figueiredo, G. F., Reis, J. L., Rocha, V. N., Melo, R. C. N., Araújo, M. G. D. F., et al. (2018) · Industrial Crops and Products · doi:10.1016/j.indcrop.2018.07.038 · Cited by 26

Substitution of threonine-1351 in the multidrug transporter Cdr1p of Candida albicans results in hypersusceptibility to antifungal agents and threonine-1351 is essential for synergic effects of calcineurin inhibitor FK520

Shukla, S. (2004) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkh308 · Cited by 25

Membrane fluidity and lipid composition of fluconazole resistant and susceptible strains of Candida albicans isolated from diabetic patients

Mishra, N. N., Prasad, T., Sharma, N., & Gupta, D. K. (2008) · Brazilian Journal of Microbiology · doi:10.1590/s1517-83822008000200004 · Cited by 25

Micafungin activity against Candida albicans with diverse azole resistance phenotypes

Richards, T. S., Oliver, B. G. G., & White, T. C. (2008) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkn156 · Cited by 25

The non-Geldanamycin Hsp90 inhibitors enhanced the antifungal activity of fluconazole.

Li, L., An, M., Shen, H., Huang, X., Yao, X., Liu, J., Zhu, F., Zhang, S., Chen, S., He, L., et al. (2015) · PubMed Central · Cited by 25

Anti-candidal Activity and Chemical Composition of Essential Oil of Clove (Syzygium aromaticum)

Alshaikh, N. A., & Perveen, K. (2017) · Journal of Essential Oil Bearing Plants · doi:10.1080/0972060x.2017.1375867 · Cited by 25

Novel Regulatory Mechanisms of Pathogenicity and Virulence to Combat MDR inCandida albicans

Hameed, S., & Fatima, Z. (2013) · International Journal of Microbiology · doi:10.1155/2013/240209 · Cited by 24

Structural basis for heterogeneous phenotype of ERG11 dependent Azole resistance in C.albicans clinical isolates

Debnath, S., & Addya, S. (2014) · SpringerPlus · doi:10.1186/2193-1801-3-660 · Cited by 24

Zebrafish Egg Infection Model for Studying Candida albicans Adhesion Factors

Chen, Y.-Z., Yang, Y.-L., Chu, W.-L., You, M., & Lo, H. (2015) · PLoS ONE · doi:10.1371/journal.pone.0143048 · Cited by 26

The evaluation of the overexpression of theERG‐11,MDR‐1,CDR‐1, andCDR‐2genes in fluconazole‐resistantCandida albicansisolated from Ahvazian cancer patients with oral candidiasis

Maheronnaghsh, M., Teimoori, A., Dehghan, P., & Fatahinia, M. (2022) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.24208 · Cited by 21

Genetic and phenotypic characterization of Candida albicans strains isolated from infectious disease patients in Shanghai

Hu, L., Du, X., Li, T., Song, Y. J., Zai, S., Hu, X., Zhang, X., & Li, M. (2014) · Journal of Medical Microbiology · doi:10.1099/jmm.0.080200-0 · Cited by 23

Effect of Chemosensitizers on Minimum Inhibitory Concentrations of Fluconazole in Candida albicans

Bulatova, N., & Darwish, R. M. (2008) · Medical Principles and Practice · doi:10.1159/000112964 · Cited by 23

New High-Throughput Screening Assay To Reveal Similarities and Differences in Inhibitory Sensitivities of Multidrug ATP-Binding Cassette Transporters

Kołaczkowski, M., Kołaczkowska, A., Motohashi, N., & Michalak, K. (2009) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00956-08 · Cited by 23

Synthetic Organotellurium Compounds Sensitize Drug-Resistant Candida albicans Clinical Isolates to Fluconazole

de Sá, L. F. R., Toledo, F. T., Gonçalves, A. C., de Sousa, B. A. A., Santos, A. A. D., Brasil, P. F., da Silva, V. A. D., Tessis, A. C., Ramos, J. A., Carvalho, M. A., et al. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01231-16 · Cited by 23

Antifungal peptides: a potential new class of antifungals for treating vulvovaginal candidiasis caused by fluconazole‐resistant Candida albicans

Ng, S. M. S., Yap, Y. Y. A., Cheong, J. W. D., Ng, F. M., Lau, Q. Y., Barkham, T., Teo, J. W. P., Hill, J., & Chia, C. S. B. (2017) · Journal of Peptide Science · doi:10.1002/psc.2970 · Cited by 23

Requirement for Ergosterol in Berberine Tolerance Underlies Synergism of Fluconazole and Berberine against Fluconazole-Resistant Candida albicans Isolates

Xu, Y., Quan, H., Wang, Y., Zhong, H., Sun, J., Xu, J., Jia, N., & Jiang, Y. (2017) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2017.00491 · Cited by 23

Antibiotic-induced alterations in taurocholic acid levels promote gastrointestinal colonization of Candida albicans

Guinan, J., & Thangamani, S. (2018) · FEMS Microbiology Letters · doi:10.1093/femsle/fny196 · Cited by 23

Detection of ERG11 point mutations in Iranian fluconazoleresistant Candida albicans isolates

Sardari, A., Zarrinfar, H., & Mohammadi, R. (2019) · Current Medical Mycology · doi:10.18502/cmm.5.1.531 · Cited by 23

Intravesicular administration of clotrimazole for treatment of candiduria in a cat with diabetes mellitus

Toll, J., Ashe, C. M., & Trepanier, L. A. (2003) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.2003.223.1156 · Cited by 23

Dispiropyrrolidine tethered piperidone heterocyclic hybrids with broad-spectrum antifungal activity against Candida albicans and Cryptococcus neoformans

Lawson, S., Arumugam, N., Almansour, A. I., Kumar, R. S., & Thangamani, S. (2020) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2020.103865 · Cited by 22

Reduced susceptibility of Candida albicans clinical isolates to azoles and detection of mutations in the ERG11 gene

Zhang, L., Yang, H., Liu, Y., Xu, X.-H., Ye, Y., & Li, J. (2013) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2013.08.018 · Cited by 22

Antifungal activity and toxicity studies of flavanones isolated from Tessaria dodoneifolia aerial parts

Soberón, J. R., Sgariglia, M. A., Torrez, J. A. C., Aguilar, F. A., Pero, E. J. I., Sampietro, D. A., de Luco, J. F., & Labadié, G. R. (2020) · Heliyon · doi:10.1016/j.heliyon.2020.e05174 · Cited by 23

Fungal Molecular Pathogenesis: What Can It Do and Why Do We Need It?

Perfect, J. R., & Casadevall, A. (2014) · ASM Press eBooks · doi:10.1128/9781555815776.ch1 · Cited by 23

General metabolism of the dimorphic and pathogenic fungus Paracoccidioides brasiliensis.

Arraes, F. B. M., Benoliel, B., Burtet, R. T., Costa, P. L. N., Galdino, A. S., Lima, L. H. A., Marinho-Silva, C., Oliveira-Pereira, L., Pfrimer, P., Procópio, L., et al. (2005) · PubMed · Cited by 21

Synthesis, Spectral Characterization, SEM, Antimicrobial, Antioxidative Activity Evaluation, DNA Binding and DNA Cleavage Investigation of Transition Metal(II) Complexes Derived from a tetradentate Schiff base bearing thiophene moiety

Aziz, A. A. A., & Seda, S. H. (2017) · Journal of Fluorescence · doi:10.1007/s10895-017-2039-9 · Cited by 21

The Intervention of Nanotechnology Against Epithelial Fungal Diseases

Higa, L. H., Schilrreff, P., Perez, A. P., Morilla, M. J., & Romero, E. L. (2012) · Journal of Biomaterials and Tissue Engineering · doi:10.1166/jbt.2013.1065 · Cited by 21

Prevalence and Fluconazole Susceptibility Profile of Candida spp. Clinical Isolates in a Brazilian Tertiary Hospital in Minas Gerais, Brazil

Neves, A., Cartágenes-Pinto, A. C., Rocha, D. A. S., de Sá, L. F. R., Junqueira, M. D. L., & Ferreira‐Pereira, A. (2015) · Anais da Academia Brasileira de Ciências · doi:10.1590/0001-3765201520140717 · Cited by 20

The antifungal properties of chicken egg cystatin againstCandidayeast isolates showing different levels of azole resistance

Kołaczkowska, A., Kołaczkowski, M., Sokołowska, A., Miecznikowska, H., Kubiak, A., Rolka, K., & Polanowski, A. (2009) · Mycoses · doi:10.1111/j.1439-0507.2009.01722.x · Cited by 20

Interactions of a prenylated flavonoid from Dalea elegans with fluconazole against azole- resistant Candida albicans

Barceló, S., Peralta, M. A., Calise, M., Finck, S., Ortega, G., Diez, R. A., Cabrera, J. L., & Pérez, C. (2017) · Phytomedicine · doi:10.1016/j.phymed.2017.05.001 · Cited by 21

Oral mycoses and other opportunistic infections in HIV : therapy and emerging problems – a workshop report

Vidya, K., Rao, U., Nittayananta, W., Liu, H., & Owotade, F. (2016) · Oral Diseases · doi:10.1111/odi.12437 · Cited by 20

Antifungal pharmacokinetics and pharmacodynamics: understanding the implications for antifungal drug resistance

Andes, D. R. (2004) · Drug Resistance Updates · doi:10.1016/j.drup.2004.06.002 · Cited by 19

Xenobiotic Efflux in Bacteria and Fungi: A Genomics Update

Barabote, R. D., Thekkiniath, J., Strauss, R. E., Vediyappan, G., Fralick, J. A., & Francisco, M. J. S. (2011) · Advances in enzymology and related areas of molecular biology/Advances in enzymology and related subjects · doi:10.1002/9780470920541.ch6 · Cited by 22

An expanded toolkit of drug resistance cassettes for Candida glabrata , Candida auris , and Candida albicans leads to new insights into the ergosterol pathway

Gregor, J. B., Gutierrez-Schultz, V. A., Hoda, S., Baker, K. M., Saha, D., Burghaze, M. G., Vazquez, C., Burgei, K. E., & Briggs, S. D. (2023) · mSphere · doi:10.1128/msphere.00311-23 · Cited by 19

Nucleotide substitutions in the Candida albicans ERG11 gene of azole-susceptible and azole-resistant clinical isolates.

Strzelczyk, J. K., Ślemp-Migiel, A., Rother, M. B., Gołąbek, K., & Wiczkowski, A. (2013) · Acta Biochimica Polonica · doi:10.18388/abp.2013_2019 · Cited by 19

Co‐Delivery of Antiviral and Antifungal Therapeutics for the Treatment of Sexually Transmitted Infections using a Moldable, Supramolecular Hydrogel

Lee, A. L. Z., Ng, V. W. L., Poon, G. L., Ke, X., Hedrick, J. L., & Yang, Y. Y. (2014) · Advanced Healthcare Materials · doi:10.1002/adhm.201400340 · Cited by 19

Molecular Principles of Antifungal Drug Resistance

Sanglard, D., & White, T. C. (2014) · ASM Press eBooks · doi:10.1128/9781555815776.ch14 · Cited by 19

The serine/threonine protein phosphatase Sit4p activates multidrug resistance in Saccharomyces cerevisiae

Miranda, M. N., Masuda, C. A., Ferreira‐Pereira, A., Carvajal, E., Ghislain, M., & Montero-Lomelı́, M. (2010) · FEMS Yeast Research · doi:10.1111/j.1567-1364.2010.00656.x · Cited by 19

Sphingolipid Inhibitors as an Alternative to Treat Candidiasis Caused by Fluconazole-Resistant Strains

Rollin‐Pinheiro, R., Bayona-Pacheco, B. L., Domingos, L. T. S., Curvelo, J. A. D. R., de Castro, G. M. M., Barreto‐Bergter, E., & Ferreira‐Pereira, A. (2021) · Pathogens · doi:10.3390/pathogens10070856 · Cited by 17

Structure-activity relationship studies of ultra-short peptides with potent activities against fluconazole-resistant Candida albicans

Ng, S. M. S., Yap, J. M., Lau, Q. Y., Ng, F. M., Ong, E. H. Q., Barkham, T., Teo, J. W. P., Alfatah, M., Kong, K. W., Hoon, S. S., et al. (2018) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2018.03.027 · Cited by 18

Genetic and phenotypic diversity of fecal Candida albicans strains in irritable bowel syndrome

van Thiel, I. A. M., Stavrou, A. A., de Jong, A. W., Theelen, B., Davids, M., Hakvoort, T. B. M., Admiraal, I., Weert, I., Hesselink, M., Vu, D., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-09436-x · Cited by 20

Synergistic Antifungal Activity of Berberine Derivative B-7b and Fluconazole

Li, L. P., Liu, W., Liu, H., Zhu, F., Zhang, D. Z., Shen, H., Xu, Z., Qi, Y. P., Zhang, S. Q., Chen, S. M., et al. (2015) · PLOS ONE · doi:10.1371/journal.pone.0126393 · Cited by 17

Antifungal Activity of Plant Secondary Metabolites on Candida albicans: An Updated Review

Khan, A., Moni, S. S., Ali, M., Mohan, S., Jan, H., Rasool, S., Kamal, M. A., Alshahrani, S., Halawi, M., & Alhazmi, H. A. (2023) · Current Molecular Pharmacology · doi:10.2174/1874467215666220304143332 · Cited by 17

Detection of ERG11 Overexpression in Candida albicans isolates from environmental sources and clinical isolates treated with inhibitory and subinhibitory concentrations of fluconazole

Oliveira, J. M. V., Oliver, J. C., Dias, A. L. T., Padovan, A. C. B., Caixeta, E. S., & Franco, M. C. (2020) · Mycoses · doi:10.1111/myc.13208 · Cited by 17

Baker’s Yeast Clinical Isolates Provide a Model for How Pathogenic Yeasts Adapt to Stress

Raghavan, V., Aquadro, C. F., & Alani, E. (2019) · Trends in Genetics · doi:10.1016/j.tig.2019.08.002 · Cited by 17

Structural design of microbicidal cationic oligomers and their synergistic interaction with azoles against Candida albicans

Yuan, Y., Zhou, F., Su, H., & Zhang, Y. (2019) · Scientific Reports · doi:10.1038/s41598-019-48322-x · Cited by 16

Erg251 has complex and pleiotropic effects on sterol composition, azole susceptibility, filamentation, and stress response phenotypes

Zhou, X., Hilk, A. L., Solis, N. V., de Sá, N. P., Hogan, B. M., Bierbaum, T. A., Poeta, M. D., Filler, S. G., Burrack, L. S., & Selmecki, A. M. (2024) · PLoS Pathogens · doi:10.1371/journal.ppat.1012389 · Cited by 18

Antifungal activity of ostholin vitroand enhancementin vivothrough Eudragit S100 nanocarriers

Li, L.-P., Wang, X., Zhang, J., Zhang, L., Cao, Y., Gu, L.-Q., Yu, Y., Yang, Q.-L., Shen, C., Han, B., et al. (2017) · Virulence · doi:10.1080/21505594.2017.1356503 · Cited by 15

Validation of the Ethnopharmacological Use of Polygonum Persicaria for its Antifungal Properties

Derita, M., & Zacchino, S. A. (2011) · Natural Product Communications · doi:10.1177/1934578x1100600702 · Cited by 16

Effects of Tamoxifen on Periodontal Disease and Candida Albicans of Patients with Breast Cancer and Other Pathologies

Muthular, M., Bálsamo, F., Passero, P., Jewtuchowicz, V. M., Miozza, V. A., Villalba, M. B., Brusca, M. I., & Pérez, C. (2019) · Future Microbiology · doi:10.2217/fmb-2018-0272 · Cited by 16

Application of the novel method in the diagnosis and treatment of median rhomboid glossitis Candida-associated

Pili, F. M. G., Erriu, M., Piras, A., & Garau, V. (2014) · European Journal of Dentistry · doi:10.4103/1305-7456.126268 · Cited by 15

Dalea Genus, Chemistry, and Bioactivity Studies

Peralta, M. A., Santi, M. D., Cabrera, J. L., & Ortega, M. G. (2019) · Studies in natural products chemistry · doi:10.1016/b978-0-444-64185-4.00008-3 · Cited by 15

Isolation of (-)-olivil-9′-O-β-d-glucopyranoside from Sambucus williamsii and its antifungal effects with membrane-disruptive action

Choi, H., Lee, J., Chang, Y. S., Woo, E., & Lee, D. G. (2013) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2013.04.023 · Cited by 15

Antifungal activity of 4-hydroxy-3-(3-methyl-2-butenyl)acetophenone against Candida albicans: evidence for the antifungal mode of action

Soberón, J. R., Lizárraga, E., Sgariglia, M. A., Juárez, M. B. C., Sampietro, D. A., Altabef, A. B., Catalán, C. A. N., & Vattuone, M. A. (2015) · Antonie van Leeuwenhoek · doi:10.1007/s10482-015-0559-3 · Cited by 15

Regulatory Role of ERG3 and Efg1 in Azoles-Resistant Strains of Candida albicans Isolated from Patients Diagnosed with Vulvovaginal Candidiasis

Feng, W., Yang, J., Xi, Z., Ji, Y., Zhu, X., Yang, L., & Ma, Y. (2019) · Indian Journal of Microbiology · doi:10.1007/s12088-019-00833-x · Cited by 15

Modulation of the Antifungal Activity of New Medicinal Plant Extracts Active on Candida glabrata by the Major Transporters and Regulators of the Pleiotropic Drug-Resistance Network in Saccharomyces cerevisiae

Kołaczkowski, M., Kołaczkowska, A., & Stermitz, F. R. (2009) · Microbial Drug Resistance · doi:10.1089/mdr.2009.0854 · Cited by 15

Antifungal Drug Resistance in Candida Species

Nagoba, B., Sheikh, N., Jahagirdar, V. L., & Kothadia, S. N. (2013) · Electronic Journal of General Medicine · doi:10.29333/ejgm/82217 · Cited by 15

Novel endoperoxides: Synthesis and activity against Candida species

Macreadie, P. I., Avery, T. D., Greatrex, B. W., Taylor, D., & Macreadie, I. G. (2005) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2005.10.101 · Cited by 15

Effect of Ethiopian multiflora honey on fluconazole-resistant Candida species isolated from the oral cavity of AIDS patients

Mulu, A., Diro, E., Tekleselassie, H., Belyhun, Y., Anagaw, B., Alemayehu, M., Gelaw, A., Biadglegne, F., Desalegn, K., Yifiru, S., et al. (2010) · International Journal of STD & AIDS · doi:10.1258/ijsa.2010.010140 · Cited by 14

Difference in virulence between fluconazole‐susceptible and fluconazole‐resistant Candida albicans in a mouse model

Schulz, B., Weber, K., Schmidt, A., Zepelin, M. B., & Ruhnke, M. (2011) · Mycoses · doi:10.1111/j.1439-0507.2010.01970.x · Cited by 14

Evaluation of virulence factors of clinical Candida isolates and the anti-biofilm activity of Elettaria cardamomum against MDR Candida albicans

Prabhakaran, V., Sengodan, T., & Rajeswari, P. (2016) · Current Medical Mycology · doi:10.18869/acadpub.cmm.2.2.3 · Cited by 14

Effects of Cetylpyridinium Chloride Resistance and Treatment on Fluconazole Activity versus Candida albicans

Edlind, M. P., Smith, W., & Edlind, T. D. (2005) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.2.843-845.2005 · Cited by 14

Characterization of caspofungin susceptibilities by broth and agar inCandidaalbicansclinical isolates with characterized mechanisms of azole resistance

Silver, P. M., Silver, P. M., Oliver, B. G. G., & White, T. C. (2008) · Medical Mycology · doi:10.1080/13693780701816557 · Cited by 14

Principles of a New Protocol for Prediction of Azole Resistance in Candida albicans Infections on the Basis of ERG11 Polymorphisms

Caban, M., Strapagiel, D., Dziadek, J., Korycka‐Machała, M., & Grzelak, A. (2016) · Current Microbiology · doi:10.1007/s00284-016-1039-3 · Cited by 13

Kangbainian Lotion Ameliorates Vulvovaginal Candidiasis in Mice by Inhibiting the Growth of Fluconazole-Resistant Candida albicans and the Dectin-1 Signaling Pathway Activation

Chen, Z., Luo, T., Huang, F., Yang, F., Luo, W., Chen, G., Cao, M., Wang, F., & Zhang, J. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.816290 · Cited by 14

Mechanisms of Drug Resistance in Fungi and Their Significance in Biofilms

Prasad, R., Shah, A. H., & Dhamgaye, S. (2014) · Springer series on biofilms · doi:10.1007/978-3-642-53833-9_4 · Cited by 13

Total synthesis and structure–activity relationships of caspofungin-like macrocyclic antifungal lipopeptides

Yao, J., Liu, H., Zhou, T., Chen, H., Miao, Z., Dong, G., Wang, S., Sheng, C., & Zhang, W. (2012) · Tetrahedron · doi:10.1016/j.tet.2012.02.015 · Cited by 14

In vitro activity of micafungin combined with itraconazole against Candida spp.

Mariné, M., Serena, C., Pastor, J., Quindós, G., Carrillo, A., & Guarro, J. (2007) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2007.06.022 · Cited by 13

Genome-wide expression profiling of the response to terbinafine in Candida albicans using a cDNA microarray analysis

Zeng, Y., Yuan-shu, Q., Ma, L., & Gu, H.-N. (2007) · Chinese Medical Journal · doi:10.1097/00029330-200705010-00013 · Cited by 13

An Azole-Tolerant Endosomal Trafficking Mutant of Candida albicans Is Susceptible to Azole Treatment in a Mouse Model of Vaginal Candidiasis

Peters, B. M., Luna-Tapia, A., Tournu, H., Rybak, J. M., Rogers, P. D., & Palmer, G. E. (2017) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00084-17 · Cited by 12

Review of Treatments for Oropharyngeal Fungal Infections in HIV/AIDS Patients

de Tilly, A. N., & Tharmalingam, S. (2022) · Microbiology Research · doi:10.3390/microbiolres13020019 · Cited by 13

Up-regulation of CDR1 and MDR1 efflux pump genes and fluconazole resistance are involved in recurrence in Candida albicans-induced vulvovaginal candidiasis

Esfahani, A., Omran, A. N., Salehi, Z., Shams‐Ghahfarokhi, M., Ghane, M., Eybpoosh, S., & Razzaghi‐Abyaneh, M. (2024) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2024.116242 · Cited by 12

Antifungal Targets, Mechanisms of Action, and Resistance in Candida albicans

Akins, R. A., & Sobel, J. D. (2009) · Humana Press eBooks · doi:10.1007/978-1-59745-180-2_29 · Cited by 12

Molecular mechanisms underlying the tetrandrine-mediated reversal of the fluconazole resistance ofCandida albicans

Zhang, X., Guo, H., Gao, L.-Q., Song, Y., Li, S., & Zhang, H. (2013) · Pharmaceutical Biology · doi:10.3109/13880209.2013.764537 · Cited by 12

cDNA Array Analysis of the Differential Expression Change in Virulence-related Genes During the Development of Resistance in Candida albicans

Xu, Z. Q., Cao, Y., Zhang, J., Cao, Y., Gao, P., Wang, D., Fu, X., Ying, K., Chen, W., & Jiang, Y. (2005) · Acta Biochimica et Biophysica Sinica · doi:10.1111/j.1745-7270.2005.00063.x · Cited by 12

First detection of mutated ERG11 gene in vulvovaginal Candida albicans isolates at Ouagadougou/Burkina Faso

Dovo, E. E., Zohoncon, T. M., Tovo, S. F., Soubeïga, S. T., Kiendrebeogo, I. T., Yonli, A. T., Ouédraogo, R. A., Dabiré, A. M., Djigma, F. W., Nadembega, C., et al. (2022) · BMC Infectious Diseases · doi:10.1186/s12879-022-07619-5 · Cited by 16

Batzelladine D, a Marine Natural Product, Reverses the Fluconazole Resistance Phenotype Mediated by Transmembrane Transporters in Candida albicans and Interferes with Its Biofilm: An In Vitro and In Silico Study

Domingos, L. T. S., de Moraes, D. C., Santos, M. F. C., Curvelo, J. A. D. R., Bayona-Pacheco, B. L., Márquez, E., Martínez, À. B., Berlinck, R. G. S., & Ferreira‐Pereira, A. (2024) · Marine Drugs · doi:10.3390/md22110502 · Cited by 11

Machine Learning for Antimicrobial Resistance Research and Drug Development

Shankarnarayan, S. A., Guthrie, J. D., & Charlebois, D. A. (2022) · IntechOpen eBooks · doi:10.5772/intechopen.104841 · Cited by 12

Multi-Locus Next-Generation Sequence Typing of DNA Extracted From Pooled Colonies Detects Multiple Unrelated Candida albicans Strains in a Significant Proportion of Patient Samples

Zhang, N., Wheeler, D. L., Truglio, M., Lazzarini, C., Upritchard, J., McKinney, W. P., Rogers, K. C., Prigitano, A., Tortorano, A. M., Cannon, R. D., et al. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01179 · Cited by 11

Synergistic effects of geldanamycin with fluconazole are associated with reactive oxygen species in Candida tropicalis resistant to azoles and amphotericin B

Jia, C., Zhang, J., Zhuge, Y., Xu, K., Liu, J., Wang, J., Li, L., & Chu, M. (2019) · Free Radical Research · doi:10.1080/10715762.2019.1610563 · Cited by 11

Peptide Motifs for Cell-Surface Intervention

Monk, B. C., & Harding, D. R. K. (2005) · BioDrugs · doi:10.2165/00063030-200519040-00005 · Cited by 11

Molecular mechanisms associated with Fluconazole resistance in clinical Candida albicans isolates from India

Mane, A. K., Vidhate, P., Kusro, C., Waman, V., Saxena, V., Kulkarni‐Kale, U., & Risbud, A. (2015) · Mycoses · doi:10.1111/myc.12439 · Cited by 41

ERG11 mutations and expression of resistance genes in fluconazole-resistant Candida albicans isolates

Xu, Y., Sheng, F., Zhao, J., Chen, L., & Li, C. (2015) · Archives of Microbiology · doi:10.1007/s00203-015-1146-8 · Cited by 37

Caracterización de los mecanismos de resistencia a azoles en aislados clínicos chilenos de Candida albicans

Fuentes, M., Hermosilla, G., Claudio Alburquenque, O., Falconer, M. A., Amaro, J., & Tapia, C. V. (2014) · Revista chilena de infectología · doi:10.4067/s0716-10182014000500001 · Cited by 6

Selected mechanisms of molecular resistance of Candida albicans to azole drugs

Gołąbek, K., Strzelczyk, J. K., Owczarek, A., Cuber, P., Ślemp-Migiel, A., & Wiczkowski, A. (2015) · Acta Biochimica Polonica · doi:10.18388/abp.2014_940 · Cited by 26

Mechanisms of azole resistance in Candida albicans clinical isolates from Shanghai, China

Liu, J.-Y., Shi, C., Wang, Y., Li, W.-J., Zhao, Y., & Xiang, M.-J. (2015) · Research in Microbiology · doi:10.1016/j.resmic.2015.02.009 · Cited by 54