The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Novel Surface Display System for Proteins on Non-Genetically Modified Gram-Positive Bacteria
Open accessAbstract
A novel display system is described that allows highly efficient immobilization of heterologous proteins on bacterial surfaces in applications for which the use of genetically modified bacteria is less desirable. This system is based on nonliving and non-genetically modified gram-positive bacterial cells, designated gram-positive enhancer matrix (GEM) particles, which are used as substrates to bind externally added heterologous proteins by means of a high-affinity binding domain. This binding domain, the protein anchor (PA), was derived from the Lactococcus lactis peptidoglycan hydrolase AcmA. GEM particles were typically prepared from the innocuous bacterium L. lactis , and various parameters for the optimal preparation of GEM particles and binding of PA fusion proteins were determined. The versatility and flexibility of the display and delivery technology were demonstrated by investigating enzyme immobilization and nasal vaccine applications.
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Cites
The Complete Genome Sequence of the Lactic Acid Bacterium Lactococcus lactis ssp. lactis IL1403
Bolotin, A., Wincker, P., Mauger, S., Jaillon, O., Malarme, K., Weissenbach, J., Ehrlich, S. D., & Sorokin, A. (2001) · Genome Research · doi:10.1101/gr.gr-1697r · Cited by 1,139
Demonstration of safety of probiotics—A review
Salminen, S. (1998) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(98)00128-7 · Cited by 884
Buist, G., Kok, J., Leenhouts, K. J., Dabrowska, M., Venema, G., & Haandrikman, A. J. (1995) · Journal of Bacteriology · doi:10.1128/jb.177.6.1554-1563.1995 · Cited by 247
Self-citationAnchoring of proteins to lactic acid bacteria
Leenhouts, K., Buist, G., & Kok, J. (1999) · Antonie van Leeuwenhoek · doi:10.1023/a:1002095802571 · Cited by 97
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Cited by
Cell Wall Structure and Function in Lactic Acid Bacteria
Chapot-Chartier, M.-P., & Kulakauskas, S. (2014) · Microbial Cell Factories · doi:10.1186/1475-2859-13-s1-s9 · Cited by 410
Vermassen, A., Leroy, S., Talon, R., Provot, C., Popowska, M., & Desvaux, M. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00331 · Cited by 348
Platforms for Production of Protein-Based Vaccines: From Classical to Next-Generation Strategies
Cid, R., & Bolívar, J. (2021) · Biomolecules · doi:10.3390/biom11081072 · Cited by 176
Immunogenicity of a malaria parasite antigen displayed by Lactococcus lactis in oral immunisations
Ramasamy, R., Yasawardena, S., Zomer, A., Venema, G., Kok, J., & Leenhouts, K. (2006) · Vaccine · doi:10.1016/j.vaccine.2006.02.040 · Cited by 102
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Metadata
- Authors
- Bosma, T., Kanninga, R., Neef, J., Audouy, S. A. L., van Roosmalen, M. L., Steen, A., Buist, G., Kok, J., Kuipers, O. P., Robillard, G., & Leenhouts, K.
- Venue
- Applied and Environmental Microbiology
- Publisher
- American Society for Microbiology
- Published
- 2006-01
- Volume
- 72
- Issue
- 1
- Pages
- 880-889
- ISSN
- 0099-2240 (ISSN-L)
- 1098-5336
- OpenAlex
- W2111339322
- Cited by
- 178
- References
- 4
- FWCI
- 2.82
- Type
- journal article
- Language
- en
- Open access
- green
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- Bosma, T., Kanninga, R., Neef, J., Audouy, S. A. L., van Roosmalen, M. L., Steen, A., Buist, G., Kok, J., Kuipers, O. P., Robillard, G., & Leenhouts, K. (2006). Novel Surface Display System for Proteins on Non-Genetically Modified Gram-Positive Bacteria. Applied and Environmental Microbiology. https://doi.org/10.1128/aem.72.1.880-889.2006
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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